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New bacteria toxins against resistant insect pests
Date:10/19/2011

esults of our experiments were encouraging but surprising. The new toxins are also effective against strains whose Bt resistance is not based on cadherin mutations," says David G. Heckel, director of the Department of Entomology at the Max Planck Institute for Chemical Ecology in Jena, Germany, and co-author of the study. Especially interesting was the finding that the new toxins were specifically effective against a super-resistant strain of tobacco budworm carrying both the cadherin mutation and another mutation affecting an ABC transporter which was discovered by the Max Planck researchers last year.

Particularly striking was the effect of Cry1AbMod and Cry1AcMod on a Bt resistant corn borer and a resistant diamondback moth strain that was 350 times stronger compared to that of the natural toxins. On the other hand, the new toxins had only a weak effect on some strains whose Bt resistance is due to a mutated cadherin.

If both novel Bt toxins prove to be useful in agriculture, they can be used in combination with different Bt toxins to guarantee a reliable effect on herbivorous pests. Biologists also agree that measures to reduce the occurrence of resistant insect pests must be strictly adhered to and that farmers should be informed in detail. Such measures would mainly include the use of different pesticides, crop rotation, and simultaneous sowing of non-Bt plants in fields, where transgenic Bt varieties are grown.


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Contact: David G. Heckel
heckel@ice.mpg.de
49-364-157-1500
Max-Planck-Gesellschaft
Source:Eurekalert  

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