Navigation Links
New atom-scale knowledge on the function of biological photosensors
Date:5/2/2014

The research groups of Janne Ihalainen (University of Jyvskyl) and Sebastian Westenhoff (University of Gothenburg) have clarified how the atom structure of bacterial red light photosensors changes when sensing light. The research reveals structural changes in phytochrome protein when illuminated.

"The results are a unique demonstration of proteins' ability to structural changes in different phases of their operation. This helps to understand how the biological photosensors function. The modelling and utilisation of protein for other applications becomes much easier when the protein structures, their changes and the speed of change are known," says Professor Ihalainen.

The function of few biological photosensors are already utilised in other fields of science, especially in neurosciences. By utilising reactions that are controlled by light, it is possible to achieve new breakthroughs in the cell biological research and, for example, in medical applications such as in phototherapy and in molecular diagnostics.

Organisms use photosensor proteins to sense light on different wavelengths. For example, mammals have rhodopsin proteins in their eyes. Phytochromes, one of the photosensor proteins of plants, fungi and bacteria, are sensitive to red light. The function of these photosensors was known already in 1970s and 1980s, but their molecular-level operating mechanisms are still unknown.

A pioneering research method

Time-resolved wide-angle X-ray scattering was used to study structural changes of this rather large protein complex in a solution form. The technique, TR-WAXS, is relatively new and in this study a successful combination of the experimental data with the molecular dynamic simulations enabled to track the detailed structural changes of the protein.

"We hope that other groups using TR-WAXS would test similar data-analysis method as well." Ihalainen says.

The light sensitive phytoch
'/>"/>

Contact: Janne Ihalainen
janne.ihalainen@jyu.fi
358-400-247-979
Academy of Finland
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Thousands of new particles in workplaces despite large knowledge gap
2. New knowledge about serious muscle disease
3. Knowledge about incontinence and pelvic organ prolapse lower among women of color
4. Reproductive biologists move in vitro fertilization knowledge forward
5. New framework to deliver biodiversity knowledge
6. New knowledge about permafrost improving climate models
7. Ag, big data, and traditional knowledge headline the Ecological Society of Americas 2013 Meeting
8. Paving the way for greater use of ancient medical knowledge
9. Disease knowledge may advance faster with CRISPR gene probing tool
10. Growing talent -- schools to provide vital knowledge for food security
11. US and French long-term ecological research networks agree to share knowledge and skills
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New atom-scale knowledge on the function of biological photosensors
(Date:12/22/2014)... Research and Markets ( ... the "The Global Watermarking and Fingerprinting ... http://photos.prnewswire.com/prnh/20130307/600769 ... the global digital media watermarking and fingerprinting ... piracy by securely and invisibly embedding identifiable ...
(Date:12/19/2014)... 18, 2014   LaunchKey , the first decentralized ... and Internet of Things era, today announced the close ... round was led by Metamorphic Ventures with participation from ... VegasTechFund, and others.  LaunchKey has raised $4 million to ... its team and bring LaunchKey to market in 2015. ...
(Date:12/17/2014)... 16, 2014 Research and Markets ... the "Global Chemical Sensor Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 One major trend ... for medical sensors in biomedical applications. Chemical sensors ... and correct diagnosis during surgical procedures. The Global ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2
... silver lining for threatened species of grizzly bears in ... bears in Alberta,s Rocky Mountain region, University of Alberta ... temperatures and easier access to food associated with forest ... known to increase the chances of successful reproduction for ...
... , October 28, 2013 Danish ... first truly affordable eye tracking device, and promise free ... cases.      (Photo: http://photos.prnewswire.com/prnh/20131028/648669 ) ... their $99 eye tracker on 29 October at TechCrunch ...
... project officially started at the beginning of October. The goal ... years so that Continental can manufacture tires made from dandelion ... research department of the automotive supplier built a pilot facility ... the ton. At the same time, they cultivate several hectares ...
Cached Biology News:Climate change has silver lining for grizzlies 2The Eye Tribe Demo $99 Eye Tracker at TechCrunch Disrupt Europe and Awards Great Ideas With Free Eye Trackers! 2The Eye Tribe Demo $99 Eye Tracker at TechCrunch Disrupt Europe and Awards Great Ideas With Free Eye Trackers! 3Fraunhofer and Continental come together when the dandelion rubber meets the road 2Fraunhofer and Continental come together when the dandelion rubber meets the road 3
(Date:12/22/2014)... , Dec. 22, 2014 /PRNewswire/ - RepliCel Life ... regenerative medicine company focused on the development of autologous ... out of the University of Calgary in conjunction with ... Carolina, which further validates the company,s ongoing clinical research ... effects of pattern baldness. The paper entitled ...
(Date:12/22/2014)... The American Journal of Hematology/Oncology, ... reviews and editorials addressing developments and pathways related ... a provocative article exploring the role of follicle-stimulating ... treatment of prostate cancer. , The article ... possibility that there could be a connection to ...
(Date:12/19/2014)... Charm Sciences is pleased to announce ... of Aflatoxin M1 in raw commingled milk is the ... validation. The peer reviewed report of the validation by ... Agricultural and Fisheries Research (ILVO-T&V) has been published by ... the most toxic aflatoxin and a known carcinogen, can ...
(Date:12/19/2014)... REDWOOD CITY, Calif. , Dec. 19, 2014 ... , USA) announced today that they have been ... Technologies 1,2 is a privately held company that ... processing of next generation sequencing (NGS) data for the ... into the Roche Sequencing Unit, and will continue to ...
Breaking Biology Technology:Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 2Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 3Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 4Newly Released Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness 5Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4Charm Sciences Achieves Independent Validation of First 15 Minute Quantitative Screening Method for Aflatoxin M1 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... decision last week to merge its Imaging and Printing Group ... Systems Group (IPSG) is a major milestone in HPs journey ... combining these two units, HP has a unified and convincing ... may be the key that turns HPs consumer message into ...
... researchers will show off developments in games that offer real-world ... ,The Academic Advanced Distributed Learning Co-Laboratory , WTN and ... how Games are Shaping Business and Learning, which will center ... applied to the workforce. , ,The video game industry has ...
... Business is booming again at the University of Wisconsin-Madisons ... job-seekers. , ,This is the best hiring situation weve seen ... associate director of ECS . Fall 2004 recruiting was ... are expected to attend Career Connection, the colleges spring job ...
Cached Biology Technology:HP charges toward the living room 2HP charges toward the living room 3Businesses and educators to preview video games for training 2Businesses and educators to preview video games for training 3Companies recruiting more UW engineering students 2Companies recruiting more UW engineering students 3Companies recruiting more UW engineering students 4
Rabbit polyclonal to Dishevelled 2 ( Abpromise for all tested applications). entrezGeneID: 1856 SwissProtID: O14641...
... Rabbit polyclonal to ErbB 2 - ... for all tested applications). ... AENPEYLGLDVPV conjugated to KLH, corresponding to ... Human c-ErbB2 Entrez ...
Anti human PPAR gamma2 mouse monoclonal antibody...
Anti-Potassium Channel Kv2.2 Immunogen: Synthetic peptide from rat Kv2.2. Available Date: 38376...
Biology Products: