Navigation Links
New artificial enzyme safer for nature
Date:10/22/2009

Perilous and polluting industrial processes can be made safer with enzymes. But only a short range of enzymes have been available for the chemical industry.

Recently a group of researchers at The Department of Chemistry at University of Copenhagen succeeded in producing an artificial enzyme that points the way to enzymes tailor-made for any application.

With their group leader, Professor Mikael Bols, Ph.d. students Jeanette Bjerre and Thomas Hauch Fenger are publishing details of their breakthrough in recognized international ChemBioChem (15/2009) under the title "Cyclodextrin Aldehydes are Oxidase Mimics"

Artificial enzymes for unnatural tasks

An enzyme unlike any seen in nature, this new one distinguishes itself in three ways. Its effect is powerful. It's easy to produce. And the researchers from the Copenhagen labs are the first to fashion an enzyme that is capable of speeding up oxidizing processes. With the simple and cheap compound Hydrogen Peroxide no less.

Oxidizing processes are considered one of the cornerstones of all chemical production. From paint to pharmaceuticals. But traditional oxidizers have a reputation for being dangerously unrefined. That's why enzymes are desirable and tailor made ones doubly so. For one thing they can be designed to be unbelievably specific. But even more important is their ability to operate under humane conditions, unlike their traditional chemical counterparts, which often need high temperatures, extreme pressure and corrosive surroundings.

New tool in the box

Until recently enzymes were exclusively found in micro organisms in the wild. But the challenges faced by microbes and chemical corporations are hardly comparable. So industries have been short on eco friendly alternatives to chemicals. The new artificial enzyme from Copenhagen adds a whole new class of tools to the toolbox of the chemists. And it's fast. Though not yet fast enough.

Natural enzymes typically speed up reactions by as much as 1 million times. The new enzyme from the Bols-group will speed up reactions by no more than 10.000 times. But that's not to be sneezed at says professor Mikael Bols.

"We have been developing these substances since year 2000. When we succeeded with the first enzyme, it's reaction speed was only multiplied by 25, so I think it's fair to speak of a breakthrough here", says the professor.

As the new enzymes inch closer to the natural reaction-times, they they are bound to become increasingly important for sensitive processes like those of the pharmaceutical industry.


'/>"/>

Contact: Jes Andersen
jean@science.ku.dk
45-3050-6582
University of Copenhagen
Source:Eurekalert

Related biology news :

1. Yale scientists create artificial cells that boost the immune response to cancer
2. M2SYS Introduces Revolutionary Biometric Artificial Intelligence Technology to Significantly Reduce Fingerprint Software False Reject Rates
3. Undergrad has sweet success with invention of artificial Golgi
4. Artificial Gravity receives 2008 Life Science Book Award
5. Complex ocean behavior studied with artificial upwelling
6. Taking the next step toward advanced artificial limbs
7. Researchers design artificial cells that could power medical implants
8. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
9. Scientists identify cell changes leading to impaired artificial kidney function
10. Biomedical researchers create artificial human bone marrow in a test tube
11. TECNALIA uses artificial vision to improve recycling of electronic scrap metal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2016)... 2016 Research and Markets has ... Market 2016-2020"  report to their offering.  , ,     ... The analysts forecast the global multimodal biometrics market ... the period 2016-2020.  Multimodal biometrics is ... as the healthcare, BFSI, transportation, automotive, and government ...
(Date:4/15/2016)... 2016  A new partnership announced today will ... decisions in a fraction of the time it ... high-value life insurance policies to consumers without requiring ... Force Diagnostics, rapid testing (A1C, Cotinine and HIV) ... pressure, weight, pulse, BMI, and activity data) available ...
(Date:4/14/2016)... AVIV, Israel , April 14, 2016 ... Behavioral Authentication and Malware Detection, today announced the appointment ... already assumed the new role. Goldwerger,s leadership ... BioCatch, on the heels of the deployment of its ... addition, BioCatch,s behavioral biometric technology, which discerns unique cognitive ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Prostate Cancer Foundation (PCF) is pleased to announce 24 new Young Investigator ... Members of the Class of 2016 were selected from a pool of 128 ... About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the ... the Supplyframe Design Lab . Located in Pasadena, Calif., the Design Lab’s ... how hardware projects are designed, built and brought to market. , The Design ...
(Date:6/23/2016)... LOUISVILLE, Ky. , June 23, 2016 /PRNewswire/ ... from two Phase 1 clinical trials of its ... double-blind, placebo-controlled, single and multiple ascending dose studies ... and pharmacodynamics (PD) of subcutaneous injection in healthy ... APL-2 subcutaneously (SC) either as a single dose ...
(Date:6/23/2016)... On Wednesday, June 22, 2016, the NASDAQ Composite ... Jones Industrial Average edged 0.27% lower to finish at 17,780.83; ... has initiated coverage on the following equities: Infinity Pharmaceuticals Inc. ... NKTR ), Aralez Pharmaceuticals Inc. (NASDAQ: ARLZ ), ... more about these stocks by accessing their free trade alerts ...
Breaking Biology Technology: