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New approach to Alzheimer's therapy
Date:7/30/2010

n of beta-amyloids.

"It is possible that less ADAM10 activity could increase susceptibility to Alzheimer's disease. If that is the case, stimulating ADAM10 could be an important mechanism for therapy. But our antibodies also open up new possibilities for diagnosing and preventing the disease," says Lichtenthaler. The antibodies could be used to measure ADAM10 activity in spinal fluid and, by extension, identify persons who may have an increased risk of developing Alzheimer's disease. A series of experiments to examine this possibility is already underway.


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Contact: Sonja Juelich-Abbas
sonja.juelich-abbas@dzne.de
49-228-433-02260
Helmholtz Association of German Research Centres
Source:Eurekalert

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