Navigation Links
New approach of resistant tuberculosis
Date:8/10/2012

only one percent had access to treatment. In 1991, a tuberculosis bug in New York was found to be resistant to 11 antibiotics. Cases have been reported where each and every antibiotic was useless. So far, these 'omniresistant' bacilli each time perished with their host before they could spread. So far, that is.

In 2012 on average 1 in 30 of new TB cases worldwide was multiresistant, with peaks of 1 in 3. With patients relapsing after a first cure, on average 1 in 5 was multiresistant, with peaks up to 65%. The highest numbers were all registered in the former Soviet Union. Without active measures the numbers will only rise.

If we want to prevent an epidemic of difficult to treat tuberculosis, then resistant cases, which do not react to the normal treatment, need to be recognized as early as possible, and immediately treated with second-line antibiotics that still work. But the laboratory tests to identify resistant TB bugs are cumbersome the WHO estimates that in 2009 only 11% of multiresistant cases were discovered.

Checking smears under the microscope still is the recommended technique for TB screening, but it cannot differentiate between living and dead bacilli. So you do not know if you are looking at the cadavers of a successful treatment, or at resistant survivors. Only if the numbers after a long wait still don't fall, you know you are dealing with a resistant strain. But all that time the patient has remained contagious.

With high-tech PCR technology one can immediately ascertain if the bacillus is from a resistant strain, but in practice and certainly in resource-limited countries this is unfeasible. It also is impossible to cultivate every sample and then bombard it with every possible antibiotic to survey which ones still work for that individual patient.

Armand Van Deun and colleagues therefore gave a new application to a forgotten technique: vital staining with fluorescein diacetate (FDA). It only stains living TB bacilli, so
'/>"/>

Contact: prof Bouke De Jong
bdejong@itg.be
32-324-76590
Institute of Tropical Medicine Antwerp
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. New line of approach for combination therapy against melanoma
2. Grassroots approach to conservation developed
3. Cancer Cell article shows first evidence for targeting of Pol I as new approach to cancer therapy
4. Scientists urge new approaches to plant research
5. Computing advances vital to sustainability efforts; new report recommends problem-focused, iterative approach to research
6. Bugs have key role in farming approach to storing CO2 emissions
7. Potential new approach to regenerating skeletal muscle tissue
8. Powerful new approach to attack flu virus
9. New approach to spell checking gene sequences
10. Scripps Florida scientist awarded $1.5 million to design therapeutics with new RNA approach
11. Manatee hearing good enough to sense approaching motorboats
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New approach of resistant tuberculosis
(Date:8/27/2014)... puts into doubt the long-standing belief that a deficiency ... plays a central role in depression. In the ... mice lacking the ability to make serotonin in their ... wisdom) did not show depression-like symptoms. , Donald ... Medical Center and Wayne State University School of Medicine ...
(Date:8/27/2014)... against trans-fats have largely succeeded in sidelining the ... sugar for its potential contributions to Americans, health ... over the best way to assuage the nation,s ... Chemical & Engineering News (C&EN), the ... , In the article, Stephen Ritter, a senior ...
(Date:8/27/2014)... shown that piglets can be weaned later with no ... of the study at the University,s Roseworthy campus, published ... an important finding for pig producers. It allows improvements ... , "Sows don,t usually start their oestrous cycles again ... have been weaned," says Ms Alice Weaver, PhD candidate ...
Breaking Biology News(10 mins):New study throws into question long-held belief about depression 2Piglet weaning age no bar to litter frequency 2
... This press release is available in French , ... STOCKHOLM (24 AUGUST 2012) As food prices ... the "super drought" in the US, a new study finds that ... and climate risks in sub-Saharan Africa and South Asia. The International ...
... 2012) A nanoparticle developed at Rice University and ... may bring great benefits to the emergency treatment of ... polyethylene glycol-hydrophilic carbon clusters (PEG-HCC), already being tested to ... studies, injections of PEG-HCC during initial treatment after an ...
... a phenomenon never seen before in plants while studying molecular ... In research published online in Proceedings of the National ... team found that one member of a family of proteins ... involved in forming wood, which includes a substance called lignin ...
Cached Biology News:Farmer-led irrigation schemes could alter food security in sub-Saharan Africa, South Asia 2Farmer-led irrigation schemes could alter food security in sub-Saharan Africa, South Asia 3Farmer-led irrigation schemes could alter food security in sub-Saharan Africa, South Asia 4Nanoparticles reboot blood flow in brain 2Nanoparticles reboot blood flow in brain 3
(Date:8/27/2014)... MONMOUTH JUNCTION, N.J. , Aug. 27, 2014 /PRNewswire/ ... developing innovative drug delivery technologies, today announced that it ... New Jersey Business & Industry Association,s 2014 Awards ... Finalists were selected by an independent panel of judges ... member company volunteers. Award winners will be honored at ...
(Date:8/27/2014)... According to the 2013 Raw Material and ... and feel of markets for raw materials and ingredient ... push for more branded, science-backed products.” , Natural products ... growth in the last decade as consumers increasingly demand ... to fit a more ‘wellness’ lifestyle approach. Due ...
(Date:8/26/2014)... what they believe is the thinnest-possible semiconductor, a ... only three atoms thick. , The University of ... single-layer semiconductor materials can be connected in an ... result could be the basis for next-generation flexible ... and solar technologies. , "Heterojunctions are fundamental elements ...
(Date:8/26/2014)... 2014 The 20 ambassadors representing the ... community issued the following statement on Facebook today regarding ... driving new funding specifically for ALS research: , “Who ... some ice would raise all this awareness and funding ... and on behalf of the entire ALS community, would ...
Breaking Biology Technology:Tris Pharma Selected as an award winner in the New Jersey Business & Industry Association's 2014 Awards for Excellence 2Daring to be Different Raw Materials & Ingredient Supply Shortage Fuels Vital Force™ Technology New Ingredient Enhancements 2Daring to be Different Raw Materials & Ingredient Supply Shortage Fuels Vital Force™ Technology New Ingredient Enhancements 3Scientists craft atomically seamless, thinnest-possible semiconductor junctions 2ALS TDI’s Young Faces of ALS Ambassadors Thank You for Accepting the Ice Bucket Challenge to End ALS 2ALS TDI’s Young Faces of ALS Ambassadors Thank You for Accepting the Ice Bucket Challenge to End ALS 3ALS TDI’s Young Faces of ALS Ambassadors Thank You for Accepting the Ice Bucket Challenge to End ALS 4
... , SAN FRANCISCO , ... a leader in Integrated Voice Response (IVR)/Integrated Web Response (IWR) ... allows users to design and deploy clinical trial Integrated Response ... of clinical trials. This time and cost savings stems from ...
... , , , , ... /PRNewswire-Asia-FirstCall/ -- Tianyin,Pharmaceutical Co., Inc., (NYSE Amex: TPI ), ... Western Pharmaceuticals,based in Chengdu, China , today announced that ... of Pricing Mechanism of Medicine,and Medical Services by the Chinese ...
... ... Divergence and National Corn Growers Association continues collaboration. , ... (PRWEB) February 9, 2010 -- Divergence, Inc. announced ... totaling $500,000, along with renewed funding from the National Corn Growers Association (NCGA), to ...
Cached Biology Technology:endpoint Saves Money and Time for Medical Research Teams Through PULSE 2endpoint Saves Money and Time for Medical Research Teams Through PULSE 3Tianyin Pharmaceutical Co., Inc. Expects to Benefit from the Recently Published Guide to Pricing Reform for Medicine and Medical Services 2Tianyin Pharmaceutical Co., Inc. Expects to Benefit from the Recently Published Guide to Pricing Reform for Medicine and Medical Services 3New Funding Validates Importance of Divergence's Work on Nematodes 2New Funding Validates Importance of Divergence's Work on Nematodes 3
Fluorescence Preserving Media, 100 mL...
Antibodies were affinity purified using epitopes specific to XLF immobilized on solid support....
...
... Clone/PAD: 3B8A10. Immunogen: ... the C-terminal region of ... Specific for the human ... Human (positive control: 293 ...
Biology Products: