Navigation Links
New approach discovered to lowering triglycerides
Date:3/30/2009

blood levels of triglycerides basically a form of fat were not thought to be as significant as cholesterol at predicting atherosclerosis and heart disease. That perspective has changed, he added, and most experts now see triglycerides as a third important risk factor for atherosclerosis, along with levels of "good" HDL and "bad" LDL cholesterol.

Widely prescribed medications are often taken to influence all of these issues, especially when efforts to control them with diet, exercise, and proper weight have not been effective. However, some of these medications have unwanted side effects that remain a concern.

In this research, it was found that supplements of lipoic acid appeared to affect triglyceride levels through two pathways. After eating, lipoic acid supplementation increased the rate of disappearance of triglycerides in the bloodstream. And supplements also reduced the genetic expression of enzymes in the liver that synthesize triglycerides.

This is the first study that has identified the molecular targets by which lipoic acid can lower triglyceride levels, the researchers said, and to show the effect on liver enzymes resulting in less production of triglycerides. It also found that the mechanism of action of how lipoic acid can lower triglycerides appears separate and distinct from that provided by fibrate drugs, a group of prescription medications often used for that purpose.

Lipoic acid supplements have in various studies been shown to be an appetite suppressant, but control groups of laboratory animals were used in this research to ensure that lower triglyceride levels were not the result simply of less food intake.

The rats used in the experiment were obese to begin with, and developed higher triglyceride levels as the experiment proceeded and they aged but the animals given lipoic acid fared much better. As they grew from five weeks of age to nine weeks, the blood triglyceride levels doubled in rats given
'/>"/>

Contact: Regis Moreau
regis.moreau@oregonstate.edu
541-737-5074
Oregon State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Team approach appears to work best for insect colonies
2. A natural approach for HIV vaccine
3. Fighting obesity and illness with a novel approach to nutrition
4. Experts discuss challenges in integrative approaches to science
5. Genetic risk factors may tailor prostate cancer screening approaches
6. A double-barreled immune cell approach for neuroblastoma
7. Avian flu threat: New approach needed
8. Novel publishing approach puts textbook in more hands
9. LIAI launches new division to look at novel approaches to heart disease and inflammation
10. Biological sand filters, a practical approach to combat poverty and inequality
11. New approach to treating cystic fibrosis lung infection shows promise
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... Ravi Birla, associate professor of biomedical engineering at ... textbook on tissue engineering and artificial organ development., ... a comprehensive guide to entering into the field ... and professor of biomedical engineering at UH, served ... said that while there are other published books ...
(Date:7/25/2014)... at the University of Adelaide has opened the way for ... powdery mildew. , In Australia, annual barley production is second ... mildew is one of the most important diseases of barley. ... discovered the composition of special growths on the cell walls ... into the leaf. , The research, by the ARC Centre ...
(Date:7/25/2014)... complex congenital central nervous system disease that is ... tubes during the embryonic phase. Many patients have ... and neurocognitive retardation. Such problems decrease the patients, ... at Ankara Physical Medicine and Rehabilitation Education and ... children with SB, using the Pediatric Evaluation of ...
Breaking Biology News(10 mins):University of Houston researcher publishes textbook on tissue engineering 2New hope for powdery mildew resistant barley 2
... FASEB Journal shows that the equivalent of one dose ... may be enough to affect fetal heart development and then ... In addition, the researchers also found that this relatively minimal ... males, when compared to those who were not exposed to ...
... began dropping dramatically in late 2008 after reaching all-time highs ... most common nitrogen fertilizer, rose from about $280 to $405 ... The price then soared to $815 per ton in Augustbut ... in mid-December. The price of diammonium phosphate (DAP) increased ...
... Igor Semiletov and Donald "Skip" Walker will be among ... Flux: New Insights from the International Polar Year, Tuesday, ... the American Geophysical Union fall meeting at the Moscone ... early results from a range of studies conducted during ...
Cached Biology News:A low dose of caffeine when pregnant may damage the heart of offspring for a lifetime 2World fertilizer prices drop dramatically after soaring to all-time highs 2UAF researchers to present at AGU press briefing 2UAF researchers to present at AGU press briefing 3UAF researchers to present at AGU press briefing 4UAF researchers to present at AGU press briefing 5UAF researchers to present at AGU press briefing 6
(Date:7/25/2014)... WABC Radio show out of New York City, ... will be hosting California-based Vet-Stem, Inc.’s Founder and CEO, Robert ... pets. Dr. Harman first visited the show in November ... pets suffering from osteoarthritis and other degenerative diseases, as well ... , Young has invited Dr. Harman back to dial down ...
(Date:7/25/2014)... 25, 2014 /PRNewswire-iReach/ -- Xybion Corporation, the leading ... corporations operating in highly regulated industries, announced today ... Global User Group Conference, Xybion International Exchange, on ... Pennsylvania at the Sheraton Society Hill ... This year,s conference theme is ...
(Date:7/24/2014)... novel combination of microscopy and data processing has given ... Laboratory an unprecedented look at the surface of a ... , The research team led by ORNL,s Zheng ... perovskite manganite, a complex material that exhibits dramatic magnetic ... behavior could benefit researchers who are interested in using ...
(Date:7/24/2014)... Calif. , July 24, 2014  ECC West ... Denver, Colorado with University College Hospital (UCH) ... a development project to finance, design, construct, and operate ... Nigeria . Under the first of ... prepare scoping documents and funding applications. UCH Ibadan intends ...
Breaking Biology Technology:Robert J. Harman, DVM, Founder and CEO of Vet-Stem, Inc. to Join New York Radio Host Lorry Young in Upcoming Episode of A “Paws” For Your Pet 2Robert J. Harman, DVM, Founder and CEO of Vet-Stem, Inc. to Join New York Radio Host Lorry Young in Upcoming Episode of A “Paws” For Your Pet 3Xybion Announces It Will Host International User Conference in Philadelphia 2Xybion Announces It Will Host International User Conference in Philadelphia 3ORNL study reveals new characteristics of complex oxide surfaces 2ECC Signs a Contract for the Finance, Design, and Construction of a Premier Cancer Institute in Ibadan, Nigeria 2
... help of 14 satellites currently in orbit and the ... scientists have been able to observe the Earths environment ... the world. The use of remote sensing technology ... the most common and deadly infectious diseases today such ...
... Ind. - Researchers have developed a new modeling ... tool that could help industry perfect lab-on-a-chip technology ... monitoring. , The experimental devices represent a new ... detect specific "target molecules," which will allow the ...
... SHANGHAI, China, Jan. 3 /Xinhua-PRNewswire/ -- WuXi PharmaTech (NYSE:,WX), ... to announce today that it has promoted Mr. Edward ... Officer., Prior to joining WuXi PharmaTech in August ... Operating Officer at Tanox, Inc., a NASDAQ listed,company later ...
Cached Biology Technology:NASA technology helps predict and prevent future pandemic outbreaks 2Model is first to compare performance of 'biosensors' 2Model is first to compare performance of 'biosensors' 3WuXi PharmaTech (NYSE: WX) Promotes Edward Hu to COO 2
Request Info...
Mouse monoclonal [B314.1 (MAC 387)] to Macrophage L1 protein Calprotectin (rating: ****) ( Abpromise for all tested applications)....
Human/Mouse/Rat AMPK beta 1 Affinity Purified Polyclonal Ab...
Immunogen: Tissue / cell preparation. (Murine EHS laminin preparation) Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biology Products: