Navigation Links
New approach alters malaria maps
Date:2/19/2013

UNIVERSITY PARK, Pa. Identifying areas of malarial infection risk depends more on daily temperature variation than on the average monthly temperatures, according to a team of researchers, who believe that their results may also apply to environmentally temperature-dependent organisms other than the malaria parasite.

"Temperature is a key driver of several of the essential mosquito and parasite life history traits that combine to determine transmission intensity, including mosquito development rate, biting rate, development rate and survival of the parasite within the mosquito," said Justine I. Blanford, research associate in geography, Penn State's the Geovista Center.

While other variables, such as the necessary rainfall to support mosquito development, also influence malaria transmission, temperature controls a variety of lifestages of both the mosquito and the malaria parasite.

The Penn State researchers include Blanford; Simon Blanford, senior research associate in biology; Robert G. Crane, professor of geography and director of Penn State's Alliance for Education, Science, Engineering and Development in Africa; Michael Mann, Distinguished Professor of Meteorology; Krijn P. Paaijmans, post doctoral researcher; and Matthew Thomas, professor in ecological entomology and Center for Infectious Disease Dynamics; and Kathleen V. Schreiber, professor of geography, Millersville University of Pennsylvania.

The researchers first looked at four locations in Kenya that represented four different climates, including warm arid conditions and cool upland conditions. They looked specifically at the Extrinsic Incubation Period, the length of time it takes for a parasite to complete development inside a mosquito from initial acquisition through an infected blood meal to transmission to a host via another blood meal. The researchers published their results in the current issue of Scientific Reports.

They found that EIP measurements based on mean monthly temperatures and mean daily temperatures were similar to each other in all cases. For the measurements based on hourly temperatures, the researchers found that for warmer locations, the EIPs were significantly longer. For cooler locations, the EIPs were substantially shorter than those calculated using mean monthly or mean daily temperatures.

"To estimate 'true' EIP we need to capture the influence of daily temperature fluctuations using hourly temperature data," said Justine Blanford. "But hourly temperature data does not exist for all locations in Kenya or across Africa."

The researchers estimated hourly temperatures using data on minimum monthly and maximum monthly temperatures. This does not equal the hourly temperatures but can be compared to the mean monthly temperatures usually used to determine malaria risk. This estimation method compared well with the data from the four Kenyan locations.

Applying this method to other locations in Kenya, they found that "mean temperatures overestimate parasite development rate under warm conditions, provide a good approximation of growth under intermediate conditions and underestimate development under cool conditions."

When looking at all of Africa, the area in and around the equator has similar EIP measurements regardless of the method used. However, there are areas in Africa where current methods over or under estimate EIP by 100 percent or more.

"The vast majority of ecological studies examining temperature-dependent effects consider mean temperature alone," said Justine Blanford.

According to the researchers, daily temperature dynamics could have marked effects on many species, affecting understanding of both current ecology and the expected responses to future climate change.


'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Related biology news :

1. UC research takes a new approach to identifying food deserts
2. Research finds promising approaches to prevent Latino childhood obesity
3. New modeling approach transforms imaging technologies
4. New, cost-cutting approach to formulating pest-killing fungi
5. Novel approach to track migration of arctic-breeding avian species
6. Choline supplementation during pregnancy presents a new approach to schizophrenia prevention
7. Stem-cell approach shows promise for Duchenne muscular dystrophy
8. Alzheimers disease: Cutting off immune response promises new approach to therapy
9. Better approach to treating deadly melanoma identified by scientists
10. Potential gene therapy approach to sickle cell disease highlighted at ASH
11. Combining two genome analysis approaches supports immune system contribution to autism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2016)... R.I. , March 31, 2016  Genomics firm ... of founding CEO, Barrett Bready , M.D., who ... members of the original technical leadership team, including Chief ... President of Product Development, Steve Nurnberg and Vice President ... returned to the company. Dr. Bready served ...
(Date:3/23/2016)... March 23, 2016 ... Sicherheit Gesichts- und Stimmerkennung mit Passwörtern ... (NASDAQ: MESG ), ein führender Anbieter ... Unternehmen mit SpeechPro zusammenarbeitet, um erstmals dessen ... wird die Möglichkeit angeboten, im Rahmen mobiler ...
(Date:3/22/2016)... Ontario , PROVO and ... Newborn Screening Ontario (NSO), which operates the ... for molecular testing, and Tute Genomics and UNIConnect, ... management technology respectively, today announced the launch of a ... next-generation sequencing (NGS) testing panel. NSO ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... June 24, 2016 , ... While the majority of commercial spectrophotometers and fluorometers ... the 6000i models are higher end machines that use the more unconventional z-dimension of ... beam from the bottom of the cuvette holder. , FireflySci has developed several ...
(Date:6/23/2016)... 2016 /PRNewswire/ - FACIT has announced the creation ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or "the ... a portfolio of first-in-class WDR5 inhibitors for the ... WDR5 represent an exciting class of therapies, possessing ... for cancer patients. Substantial advances have been achieved ...
(Date:6/23/2016)... 2016  The Biodesign Challenge (BDC), a university competition ... harness living systems and biotechnology, announced its winning teams ... New York City . The ... projects at MoMA,s Celeste Bartos Theater during the daylong ... senior curator of architecture and design, and Suzanne ...
(Date:6/23/2016)... Apellis Pharmaceuticals, Inc. today announced positive ... its complement C3 inhibitor, APL-2. The trials were ... studies designed to assess the safety, tolerability, pharmacokinetics ... healthy adult volunteers. Forty subjects were ... dose (ranging from 45 to 1,440mg) or repeated ...
Breaking Biology Technology: