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New anticoagulant discovered based on the same used by malaria vectors to feed on
Date:12/11/2012

s protein, i.e. they changed the amino acid at each time, so as to discover the crucial components of the molecule when it interacted with thrombin.

Blood coagulation is a complex mechanism to prevent bleeding after an injury. However, in some cases, the formation of blood clots can lead to a myocardial infarction, a cerebral infarction etc. In these cases, administering anticoagulants is essential. Anticoagulants are drugs that prevent blood from coagulating, thus avoiding cardiovascular events, which are the leading cause of death in Spain. In recent years, one of the most active fields of research has been the search for the ideal anticoagulant since the ones available today may have side effects and must be administered under strict medical control. "The discovery of this new interaction could be useful in the future to create new generation anticoagulant drugs that improve these aspects and also to fight against the spreading of malaria" concludes Dr. Gutirrez Gallego.


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Contact: Marta Calsina
mcalsina@imim.es
34-933-160-680
IMIM (Hospital del Mar Medical Research Institute)
Source:Eurekalert

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