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New antibiotic candidates from Braunschweig
Date:10/17/2008

of the genetic materials is suppressed completely. This new mechanism also operates in bacteria that are resistant to conventional antibiotics.

For Jansen and Irschik the results of the US researchers signalize that their substances now are facing a long process of development: " In their present form myxopyronin, corallopyronin and ripostatin are not yet applicable as antibiotics," explains Irschik. Further chemical development is now required, as Jansen adds: "Our natural agents are so-called chemical leads, which the chemists will modify in detail in order to increase their antibiotic action and minimize side-effects. This development will include extensive testing, which may take several years, before the new medicine will reach the hands of doctors finally."


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Contact: Hannes Schlender
hannes.schlender@helmholtz-hzi.de
49-531-618-11400
Helmholtz Association of German Research Centres
Source:Eurekalert

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