Date:1/2/2013

rred from advancement into final monograph status based on public comments received that indicated the monograph needed to be strengthened with quantitative test requirements for phospholipids. Phospholipids are important biological chemicalsand krill phospholipids contain the omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Considerable outside research is being conducted on these types of phospholipids and their potential health benefits in the areas of heart and cardiovascular health, joint health, women's health and brain health. Many of these purported benefits are associated with the specific DHA and EPA fatty acids that are attached to phospholipids in krill oil. The revised version of this monograph, reflective of comments received, proposes both qualitative (fingerprint) and quantitative tests for total phospholipid content as well as one of the key phospholipidsphosphatidylcholinewhich is believed to be linked to certain health benefits.

Steviol GlyosidesFirst proposed in the December 2011 FCC Forum, a revised new monograph proposal incorporating comments and suggestions from stakeholders for the naturally derived sweetener provides a more simplified approach for separating and measuring all nine glycosides present in the stevia leaf. USP also has a monograph for high purity Rebaudioside A, the first stevia-based sweetener widely used in the United States and Europe. A range of steviol glycosides, including mixtures of different glycosides, are now being used in a variety of products in addition to Rebaudioside A. For regulatory compliance, formulation considerations (e.g., different glycosides may have different sweetener profiles) and other reasons, it is critical for manufacturers to be able to accurately identify the material they have sourced. According to the International Stevia Council, more than 56 million households in the United States have stevia and stevia-sweetened products in their homes. The new F
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Contact: Francine Pierson fp@usp.org 301-816-8588 US Pharmacopeia Source:Eurekalert

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