Navigation Links
New York University scientists discover possible treatment to reduce scarring
Date:7/6/2012

Bethesda, MDWhether from surgery or battle wounds, ugly scars can affect body and mind. Now a new research report appearing online in the FASEB Journal offers a new strategy to reduce or eliminate scars on the skin. Specifically, scientists from NYU describe how agents that block receptors for adenosine (a molecule generated from ATP which is used by the body to provide energy to muscles) can be applied topically to healing wounds to reduce scar size, yielding skin that feels more like the original, unscarred skin.

"Scars can be disfiguring and, if extensive enough, can lead to diminished function and quality of life," said Bruce N. Cronstein, M.D., a researcher involved in the work from the Division of Translational Medicine in the Department of Medicine at New York University School of Medicine in New York, NY. "We hope that our findings may lead to new agents that diminish scarring and disfigurement following burns, wounds, or even illnesses that destroy skin and lead to a better quality of life for victims of these traumas."

When the skin or other tissues are wounded, ATP leaks from the damaged cells and is then converted to adenosine which promotes healing. Scars form when adenosine continues to be produced at the wound site after the injury is healed, leading to larger, thicker scars than what may have otherwise been there. To study the possibility of reducing scar sizes, Cronstein and colleagues studied wounds on the backs of mice. After the wound closed, the adenosine A2A receptor antagonist was applied. They found that the adenosine A2A receptor agonist prevented excessive scar tissue in the treated mice.

"The vast majority of scars are hardly noticeable, if they can be seen at all," said Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal, "but for some, scars can severely disfigure not only the body, but the mind. Finding ways to prevent scarring after wounds or surgery has the potential to improve the quality of life for those who suffer the slings and arrows of outrageous fortune, now and for generations to come."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Related biology news :

1. Royal Astronomical Society and Oxford University Press partnership announced
2. Mainz University coordinates new EU project on the origins of human settlement
3. University of Tennessee professor receives funding for clean coal research
4. University of North Texas Health Science Center Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology
5. IOC recognizes University of Calgary Sports Injury Research Prevention Centre
6. Loss of biodiversity increasingly threatens human well-being: UBC, University of Michigan research
7. NIH supporting Arizona State University research to help in fight against kidney disease
8. University of Tennessee anthropologists find American heads are getting larger
9. Wells Fargo fosters environmental conservation through University of Miamis RJD program
10. University of Leicester study finds low agreeableness linked to a preference for aggressive dogs
11. University of Hawaii Cancer Center researchers create new anti-cancer drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... 2017  Hunova, the first robotic gym for the rehabilitation and functional ... in Genoa, Italy . The first 30 robots will ... USA . The technology was developed and patented at ... IIT spin-off Movendo Technology thanks to a 10 million euro investment from ... click: ...
(Date:4/24/2017)... 24, 2017 Janice Kephart , ... Identity Strategy Partners, LLP (IdSP) , today issues ... President Trump,s March 6, 2017 Executive Order: ... vetting can be instilled with greater confidence, enabling ... all refugee applications are suspended by until at ...
(Date:4/13/2017)... UBM,s Advanced Design and Manufacturing event in ... and evolving technology through its 3D Printing and Smart ... the expo portion of the event and feature a ... on trending topics within 3D printing and smart manufacturing. ... will take place June 13-15, 2017 at the Jacob K. ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... PITTSBURGH, PA (PRWEB) , ... October 10, 2017 ... ... this year’s recipients of 13 prestigious awards honoring scientists who ... be presented in a scheduled symposium during Pittcon 2018, the world’s leading conference ...
(Date:10/9/2017)... ... ... The award-winning American Farmer television series will feature 3 Bar Biologics in ... 8:30aET on RFD-TV. , With global population estimates nearing ten billion people by ... feed a growing nation. At the same time, many of our valuable resources are ...
(Date:10/9/2017)... ... October 09, 2017 , ... The Giving ... marijuana products targeting the needs of consumers who are incorporating medical marijuana into ... in Phoenix, Arizona. , As operators of two successful Valley dispensaries, The Giving ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... applications consulting for microscopy and surface analysis, Nanoscience Instruments is now expanding ... offers a broad range of contract analysis services for advanced applications. Services ...
Breaking Biology Technology: