Navigation Links
New York Stem Cell Foundation scientist grows bone from human embryonic stem cells
Date:5/14/2012

NEW YORK, NY (May 14, 2012) -- Dr. Darja Marolt, an Investigator at The New York Stem Cell Foundation (NYSCF) Laboratory, is lead author on a study showing that human embryonic stem cells can be used to grow bone tissue grafts for use in research and potential therapeutic application. Dr. Marolt conducted this research as a post-doctoral NYSCF Druckenmiller Fellow at Columbia University in the laboratory of Dr. Gordana Vunjak-Novakovic.

The study is the first example of using bone cell progenitors derived from human embryonic stem cells to grow compact bone tissue in quantities large enough to repair centimeter-sized defects. When implanted in mice and studied over time, the implanted bone tissue supported blood vessel ingrowth, and continued development of normal bone structure, without demonstrating any incidence of tumor growth.

Dr. Marolt's work is a significant step forward in using pluripotent stem cells to repair and replace bone tissue in patients. Bone replacement therapies are relevant in treating patients with a variety of conditions, including wounded military personnel, patients with birth defects, or patients who have suffered other traumatic injury.

Since conducting this work as proof of principle at Columbia University, Dr. Marolt has continued to build upon this research as an Investigator in the NYSCF Laboratory, developing bone grafts from induced pluripotent stem (iPS) cells. iPS cells are similar to embryonic stem cells in that they can also give rise to nearly any type of cell in the body, but iPS cells are produced from adult cells and as such are individualized to each patient. By using iPS cells rather than embryonic stem cells to engineer tissue, Dr. Marolt hopes to develop personalized bone grafts that will avoid immune rejection and other implant complications.


'/>"/>

Contact: David McKeon
dmckeon@nyscf.org
212-365-7440
New York Stem Cell Foundation
Source:Eurekalert

Page: 1

Related biology news :

1. Michael J. Fox Foundation grant to Dr. Samuel Young will provide Parkinsons drug development tools
2. Merkin Family Foundation to fund next generation of Broad Institute scientists
3. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
4. ASBMB wins National Science Foundation grant to enhance K-12 science education
5. 2012 ACMG Foundation/Signature Genomic Laboratories Travel Award winner announced
6. Genzyme/ACMG Foundation Genetics Training Award in Clinical Biochemical Genetics announced
7. John A. Kaufman named 2012 Dotter Lecturer by Society of Interventional Radiology Foundation
8. Renowned geneticist R. Rodney Howell receives ACMG Foundation Lifetime Achievement Award
9. Kessler Foundation implements Ekso Bionics first commercial robotic exoskeleton
10. Celebrity Golf Classic raises $553,443 for Seena Magowitz Foundation
11. Wayne State-licensed technology receives grant from the Foundation Fighting Blindness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/11/2016)... Germany , March 11, 2016 http://www.apimages.com ... - Cross reference: Picture is available at AP Images ( http://www.apimages.com ... from DERMALOG will be used to produce the new refugee identity ... other biometric innovations, at CeBIT in Hanover ... scanner from DERMALOG will be used to produce the new refugee ...
(Date:3/9/2016)... , March 9, 2016 ... government identified that more than 23,000 public service employees ... had been receiving their salary unlawfully.    --> ... country,s government identified that more than 23,000 public service ... or had been receiving their salary unlawfully.    ...
(Date:3/3/2016)... and DE SOTO, Kansas , March ... Detection Plus® to offer Oncimmune,s Early CDT®-Lung, a ... early detection of lung cancer Early CDT®-Lung ... and individuals. --> Early CDT®-Lung test to ... --> Oncimmune, a leader in early cancer ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... ... May 03, 2016 , ... Nashville Fertility Center has ... contingency of reproductive endocrinologists, including Dr. George Hill at Nashville Fertility ... help them build families. , Ovation Fertility is a nationwide network of leading ...
(Date:5/2/2016)... ... May 02, 2016 , ... F.E.E.D. Co., the Feline Environmental ... revolutionary, veterinarian-designed product for indoor cats. The NoBowl Feeding System replaces the bowl ... the way nature intended. NoBowls make cats happy and healthy. , Since being ...
(Date:4/29/2016)... 2016 According to a ... "Separation Systems for Commercial Biotechnology Market - Global ... 2015 - 2023", the separation systems for commercial ... in 2014 and is projected to expand at ... to reach US$ 19,227.8 Mn in 2023. ...
(Date:4/29/2016)... Italy , April 29, 2016 ... 5.11, the latest update to its industry-leading treatment planning ... shown that Monaco version 5.11 ... can now attain calculation speeds up to four times ... . With the industry,s gold standard ...
Breaking Biology Technology: