Navigation Links
New York Stem Cell Foundation scientist grows bone from human embryonic stem cells
Date:5/14/2012

NEW YORK, NY (May 14, 2012) -- Dr. Darja Marolt, an Investigator at The New York Stem Cell Foundation (NYSCF) Laboratory, is lead author on a study showing that human embryonic stem cells can be used to grow bone tissue grafts for use in research and potential therapeutic application. Dr. Marolt conducted this research as a post-doctoral NYSCF Druckenmiller Fellow at Columbia University in the laboratory of Dr. Gordana Vunjak-Novakovic.

The study is the first example of using bone cell progenitors derived from human embryonic stem cells to grow compact bone tissue in quantities large enough to repair centimeter-sized defects. When implanted in mice and studied over time, the implanted bone tissue supported blood vessel ingrowth, and continued development of normal bone structure, without demonstrating any incidence of tumor growth.

Dr. Marolt's work is a significant step forward in using pluripotent stem cells to repair and replace bone tissue in patients. Bone replacement therapies are relevant in treating patients with a variety of conditions, including wounded military personnel, patients with birth defects, or patients who have suffered other traumatic injury.

Since conducting this work as proof of principle at Columbia University, Dr. Marolt has continued to build upon this research as an Investigator in the NYSCF Laboratory, developing bone grafts from induced pluripotent stem (iPS) cells. iPS cells are similar to embryonic stem cells in that they can also give rise to nearly any type of cell in the body, but iPS cells are produced from adult cells and as such are individualized to each patient. By using iPS cells rather than embryonic stem cells to engineer tissue, Dr. Marolt hopes to develop personalized bone grafts that will avoid immune rejection and other implant complications.


'/>"/>

Contact: David McKeon
dmckeon@nyscf.org
212-365-7440
New York Stem Cell Foundation
Source:Eurekalert

Page: 1

Related biology news :

1. Michael J. Fox Foundation grant to Dr. Samuel Young will provide Parkinsons drug development tools
2. Merkin Family Foundation to fund next generation of Broad Institute scientists
3. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
4. ASBMB wins National Science Foundation grant to enhance K-12 science education
5. 2012 ACMG Foundation/Signature Genomic Laboratories Travel Award winner announced
6. Genzyme/ACMG Foundation Genetics Training Award in Clinical Biochemical Genetics announced
7. John A. Kaufman named 2012 Dotter Lecturer by Society of Interventional Radiology Foundation
8. Renowned geneticist R. Rodney Howell receives ACMG Foundation Lifetime Achievement Award
9. Kessler Foundation implements Ekso Bionics first commercial robotic exoskeleton
10. Celebrity Golf Classic raises $553,443 for Seena Magowitz Foundation
11. Wayne State-licensed technology receives grant from the Foundation Fighting Blindness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... high levels of vitamin D in their blood are more ... Patients with the highest levels of vitamin D have half ... levels, the findings reveal. , The study is the first ... cancer patients after their diagnosis which includes that produced ... with their long term survival prospects. , The ...
(Date:7/9/2014)... data can yield big savings, if they are ... Bates of the Brigham and Women,s Hospital and ... for cost savingshigh-cost patients; readmissions; triage; decompensation (when ... optimization when a disease affects multiple organ systems. ... though the current costs associated with all six ...
(Date:7/8/2014)... increased risk of severe perineal tearing during childbirth in women ... a new study published today (9 July) in BJOG: ... This study, investigates among women who have had a third ... subsequent pregnancies and the recurrence of severe perineal tears. ... in some women the tear may be more extensive. A ...
Breaking Biology News(10 mins):The impact of big data on health care: Health Affairs' July issue 2Mode of delivery following a perineal tear and recurrence rate in subsequent pregnancies 2
... Mich.---Researchers have developed what they believe is the first new ... used to treat all HIV patients, which could eventually lead ... the University of Michigan used computer models to develop the ... compound does indeed inhibit HIV protease, which is an established ...
... Oregon white oak were once widespread in the Pacific ... Fire suppression, conifer and invasive plant encroachment, and land ... much as 99 percent of the oak communities historically ... new technical report titled "Evaluation of Landscape Alternatives for ...
... experts on evolution will gather in Minnesota June 20 ... gathering of evolutionary biologists. The conference, the premier international ... is sponsored by the University of Minnesota,s Bell Museum ... and Minnesota Citizens for Science Education. Headlining the ...
Cached Biology News:Compound has potential for new class of AIDS drugs 2University of Minnesota to host world's largest conference on evolution 2
(Date:1/15/2014)... Look inside the new Preferred Solutions® ... lab, from fluid handling to instruments to supplies. Many ... you order. , Preferred Solutions features a full ... L/S® model for precise flow control and dispensing to ...
(Date:1/15/2014)... England , January 15, 2014 A ... win races on the Formula 1 track could help to ... McLaren Applied Technologies (MAT), Stowhealth (a GP surgery based in ... by healthcare provider Simplyhealth. Telemetry technology, which is ...
(Date:1/15/2014)... 15, 2014 2013 was a banner ... State Technologies®. They saw continued independent research led by ... were awarded a $1 million grant from the Susanne ... and Behavior” a peer reviewed journal, Amy Grant highlighted ...
(Date:1/14/2014)... Washington, DC (PRWEB) January 14, 2014 ... session for Thursday, January 23, 2014 at 2pm EST ... Actionable Knowledge.” The topic focuses on how technology can ... mission critical decisions for government agencies. The online webinar ...
Breaking Biology Technology:Cole-Parmer Begins 2014 with the Release of Preferred Solutions 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2
... young company with a preventive solution to identity theft took ... Burrill Technology Business Plan Competition, but if area investors want ... act quickly. , , Din and Newport stand in ... Khaja M. Din, president IPIC (Internet Privacy & ...
... of capturing 10 percent of the stem cell technology market ... directing the Department of Commerce to spend at least $5 ... companies to Wisconsin. , ,Doyle said the executive order, signed ... to stem cell research. Proponents of stem cell research cite ...
... and services to the financial and health-benefits industries, said ... to $1.1 billion. , ,Net income was $116 million, ... in the first quarter of 2005 on $973 million ... included repurchasing 5.4 million shares of common stock and ...
Cached Biology Technology:Winner of Burrill competition courted by North Carolina investors 2Winner of Burrill competition courted by North Carolina investors 3Doyle authorizes $5 million to woo stem cell companies 2
... numbers of samples may be carried out using ... minimum operator attention. System control and data ... CE 4900. The elegant, powerful and very ... and Windows 98 and 2000., The supplied automatic ...
Heavy-duty rim. Especially recommended as a titration flask. Corning5100. capacity 250 mL Special grade: student grade...
This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (F1676) or contact customer s...
Mouse monoclonal [YPF19] to Yersinia pestis F1 antigen ( Abpromise for all tested applications)....
Biology Products: