Navigation Links
New X-ray method shows how frog embryos could help thwart disease
Date:5/17/2013

LEMONT, Ill. An international team of scientists using a new X-ray method recorded the internal structure and cell movement inside a living frog embryo in greater detail than ever before.

This result showcases a new method to advance biological research and the search for new treatments for genetic diseases.

Scientists at Northwestern University and the Karlsruher Institut fr Technologie in Germany, in collaboration with the Advanced Photon Source at the U.S. Department of Energy's Argonne National Laboratory, released the most precise depiction ever of the embryonic development of African clawed frogs, one of the most frequently studied model organisms in biology.

The results titled "X-ray phase-contrast in vivo microtomography probes new aspects of Xenopus gastrulation" were published May 16 in the journal Nature.

The team X-rayed an embryo during gastrulation, the period when its hundreds of cells start to organize into differentiated tissues that eventually form the nervous system, muscles and internal organs. Studies of African clawed frog embryos can provide clues to the evolution of vertebrates and how human genes turn on or off to create diseases.

Until now, however, it has been difficult to study these embryos. Classical absorption imaging requires a contrast agent and large X-ray dose that can harm living organisms. Researchers from the German synchrotron ANKA proposed a new method of nondestructive analysis using X-ray diffraction. The work was done at the APS outside Chicago because the APS's high-energy X-rays were required to prevent blurring of the image and damage to the sensitive embryos.

"To obtain the best possible results, a highly coherent high-energy X-ray source with high flux is necessary," said Xianghui Xiao, a scientist at the APS who collaborated on the work. "The APS is one of only a few X-ray lightsources in the world with this capability. The upgrade of the APS will further improve our ability to
'/>"/>

Contact: Jared Sagoff
jsagoff@anl.gov
630-252-5549
DOE/Argonne National Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. Dental X-rays linked to common brain tumor
2. Stanford-SLAC team uses X-ray imaging to observe running batteries in action
3. Speed and power of X-ray laser helps unlock molecular mysteries
4. Low-cost carbon capture gets X-rayed
5. X-rays reveal the self-defence mechanisms of bacteria
6. Study provides recipe for supercharging atoms with X-ray laser
7. X-ray laser helps slay parasite that causes sleeping sickness
8. Scientists reassemble the backbone of life with a particle acceleratorynchrotron X-rays
9. X-rays reveal uptake of nanoparticles by soya bean crops
10. Improved X-ray microscopic imaging
11. A dual look at photosystem II using the worlds most powerful X-ray laser
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... addition of the "Global Facial Recognition Market ... http://photos.prnewswire.com/prnh/20130307/600769 Facial ... of individuals. Facial recognition system measures the overall ... jaw edges, mouth, and the distance between eyes. ...
(Date:12/11/2014)... SALEM, N.C. , Dec. 10, 2014  That blood ... for quite a while. Hypertension – the medical term for ... in the early 1800s, and the inflatable cuff that,s used ... That doesn,t, however, mean there,s nothing new about hypertension, its ... some long-held beliefs about the condition and the best ways ...
(Date:12/10/2014)... 9, 2014  Valencell, a leader in performance biometric ... staggering demand from its licensees for highly accurate, clinically ... not solely coming from fitness and health sectors, but ... "A wearable is only as useful as the biometric ... ultimate driver in long-term mass consumer adoption of wearable ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Wearable Technology Products Demand Highly Accurate Biometric Technology 2
... egg question. Where do the infectious protein particles called ... cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, in ... of their properly folded protein counterparts, but they usually ... Biochemists at Emory University School of Medicine have identified ...
... Institute of Molecular and Cell Biology (IMCB) has discovered ... deadly plant toxin Ricin, widely feared for its bioterrorism ... for the tens of thousands of hospital-acquired infections in ... this first ever genome-wide study to understand how the ...
... sometimes have its advantages. That,s according to a study of ... native Chilean forest. The data show that the pollinators those ... of resources found in agricultural lands. As a result, trees ... successfully when separated by resource-poor pine plantations than by those ...
Cached Biology News:Cellular stress can induce yeast to promote prion formation 2A*Star scientists discover how to combat hospital-acquired infections and life-threatening toxins 2A*Star scientists discover how to combat hospital-acquired infections and life-threatening toxins 3As agricultural riches waylay pollinators, an endangered tree suffers 2As agricultural riches waylay pollinators, an endangered tree suffers 3
(Date:12/17/2014)... 17, 2014 Audacity, a leading California-based ... member of the Huntsworth Health Group, is proud to ... team. In her role, Gonzales will serve as Senior ... incredibly honored to welcome a talent of Jamie’s caliber ... Gaëtan Fraikin. “She is a proven healthcare innovation leader ...
(Date:12/17/2014)... 2014  United Therapeutics Corporation (NASDAQ: UTHR ... as changes to Martine Rothblatt , Ph.D,s compensation ... United Therapeutics announced the promotion of Roger ... and David Zaccardelli , Pharm.D. to Executive Vice ... promotions, Dr. Rothblatt,s title will change from Chairman and ...
(Date:12/17/2014)... 17, 2014 Tigercat Pharma, Inc. today ... evaluating the investigational oral NK-1 receptor antagonist VPD-737 ... chronic itch who are unresponsive or inadequately responsive ... steroids and antihistamines. The primary ... Scale (VAS) itch score from baseline, comparing drug ...
(Date:12/15/2014)... (PRWEB) December 15, 2014 METTLER ... inline PVM tool, ParticleView V19 with PVM ... situ probe-based particle vision and measurement tool continuously ... process conditions. ParticleView V19 then automatically prepares a ... tracking particle size and concentration changes. This compelling ...
Breaking Biology Technology:Audacity Welcomes Healthcare Communications Expert Jamie Gonzales as Senior Vice President of Client Services 2United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 2United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 3United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 4Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4New Real-Time In Situ Probe-Based Video Microscope from METTLER TOLEDO 2
... will seek additional venture funding this year in ... president and CEO Loren G. Peterson said. , ,Peterson ... the Innovation Monday program. He said ZyStor, which is ... filing the application for its lead product in early ...
... Wis. - For the second time in six ... giant, claiming patent infringement. , ,This time Hyperphrase Technologies ... Internet search engine company, for allegedly using technology that ... other sites or advertisements. Hyperphrase claims that Google Toolbar ...
... enjoyed another year of impressive growth, according to the ... a quarterly publication on the trademark industry published by ... and online brand monitoring services. , ,The report provides ... trademark filing activity, a ranking of leading trademark law ...
Cached Biology Technology:Milwaukee area biotech ZyStor seeks more funding 2Milwaukee area biotech ZyStor seeks more funding 3
... Costar strip ejector is a unique product ... strips from their holder. Linkage: This CLS ... to easily match Cornings product number. If ... the old Sigma-Aldrich number (Z71,314-7) or contact ...
...
... The ideal modular cleanroom for biological ... that require cleanliness (to Class 10/ISO ... precision-joined to create ultra-smooth surfaces that ... disinfect. One-inch radius corners simplify cleaning. ...
This free-standing work station safely ventilates fumes upwards, away from the work surface. Optional Exhaust Purification System features bonded charcoal filters that remove organic chemical vapors ...
Biology Products: