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New UC sensor promises rapid detection of dangerous heavy metal levels in humans
Date:8/1/2011

ped a thin-film bismuth working electrode vs. the conventional mercury or carbon electrode. The favorable performance of the bismuth working electrode combined with its environmentally friendly nature means the new sensor will be especially attractive in settings where a disposable lab-on-a-chip is wanted.

In addition, the UC team also optimized the sensor layout and working-electrode surface to further reduce the effects of hydrolysis and to boost the reliability and sensitivity in detecting heavy metals. The new sensor layout better allowed for its functioning, which consists of taking of a blood serum sample, stripping out the heavy metal and then measuring that heavy metal.

The end result is the first lab-on-a-chip able to consistently pinpoint levels of highly electronegative manganese in humans. The new sensor also exhibits high reliability over multiple days of use, with hours of continuous operation. With further developments, the chip may even be converted into a self-check mechanism, such as with glucose screening for diabetics.


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Contact: M.B. Reilly
reillymb@ucmail.uc.edu
513-556-1824
University of Cincinnati
Source:Eurekalert  

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