Navigation Links
New Translational Addiction Sciences Center poised to make headway in treatment of addiction
Date:4/25/2014

lators of the mechanisms underlying addiction. "Targeting the serotonin system is a novel approach for treatment of drug addiction and relapse," said Gilbertson. "Scientists have examined other aspects of the central nervous system, like the dopamine neurotransmitter system, for a long time with little success."

Cunningham noted that it is well known that an imbalance in the serotonin system in the brain is related to depression and anxiety; however, "our scientific advances are now bringing to light the importance of serotonin in cocaine addiction and implicate serotonin imbalance as a mechanism underlying certain behavioral traits that enhance susceptibility to relapse."

Individuals who tend to act on impulse and show elevated responses to cues associated with cocaine use have a higher incidence of relapse. Targeting individuals who express these behavioral traits is an additional unique and innovative aspect of these investigations.

"These factors are interconnected and appear to be related to an underlying imbalance in serotonin receptor function, providing an opportunity to individualize treatment strategies," said Moeller. "We believe that addicted patients who exhibit these particular traits will respond better to medications that selectively target certain serotonin receptors."

The serotonin receptor system, however, is complex, consisting of at least 14 different receptor proteins, and current medications that act on this system do not distinguish the receptor subtypes very well. Thus, there is a need to develop new compounds that selectively target the desired receptors.

That is where the chemists and cell biologists come in. "When new compounds are synthesized by Dr. Gilbertson's group, the effects of these compounds are first measured at the cellular level because it is much more efficient, less costly, and reduces the number of animal and human evaluations necessary," said Watson. These technologies will give the team n
'/>"/>

Contact: Maureen Balleza
maballez@utmb.edu
409-772-8785
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Elsevier launches new open access journal: Applied and Translational Genomics
2. Autism Speaks and SAGE® Labs develop rat models for translational autism research
3. Hot topics in translational bone research at IOF-ESCEO 3rd Pre-Clinical Symposium
4. IMPAKT -- Translational research breast cancer conference
5. Center for Clinical and Translational Science awards new pilot grants
6. Elsevier launches new open access journal: Translational Proteomics
7. Drug development venture links translational research, business to launch new therapeutics
8. Lab-on-a-chip tech, brain mapping & microbiome highlighted at translational med meeting
9. NIH awards Scripps Translational Science Institute $29 million grant
10. Singapore joins global translational medicine network as Asia-Pacific hub
11. FASEB announces 2014 SRC: Translational Neuroimmunology: From Mechanisms to Therapeutics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2014)... MOUNTAIN VIEW, Calif. , Dec. 4, 2014 ... and safety has boosted investments in new testing ... products has also given rise to a range ... driven by the requirements of Generation Y, which ... digital technologies. As a result, product development strategies ...
(Date:11/21/2014)... According to a new market research report ... Control, Intrusion Detection, Parking Management, Under Vehicle Inspection), End ... - Global Forecasts to 2020", published by MarketsandMarkets, The ... $25 Billion in 2014 and is expected to reach ... 8.69%. Browse 116 market data Tables and ...
(Date:11/18/2014)... -- The Secure Identity & Biometrics Association (SIBA) and ... formation of The Airport Entry and Exit Working ... Biometric Entry and Exit Solutions Framework for Airports ... BORDERPOL, the international non-profit organization that works directly ... border security, traveler and migration systems. ...
Breaking Biology News(10 mins):Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3
... Disorders and Stroke (NINDS), a component of the National Institutes ... the Morris K. Udall Centers of Excellence in Parkinson,s Disease ... totaling more than $16 million for Emory University in Atlanta ... NINDS Director Story Landis, Ph.D., announced the ...
... the future" story, scientists today reported that the sustainable, ... ago is re-emerging as a "green" alternative to wood ... the American Chemical Society, they described development of new ... and tofu and could mean a new generation of ...
... increase of up to 4.2 C and the end ... targets are not revised in the Copenhagen Accord, the international ... change conference. Just ahead of the next ... in Tianjin, China, a new report published today, Wednesday, 29 ...
Cached Biology News:NINDS awards new Udall Centers for Parkinson's Disease Research 2NINDS awards new Udall Centers for Parkinson's Disease Research 3Climate accord loopholes could spell 4.2-degree rise in temperature and end of coral reefs by 2100 2
(Date:12/24/2014)... “Preparative & Process Chromatography Market by Instrument ... Buffers, Valves, Guages, Seals), Accessories, Services, End User ... 2019” provides a detailed overview of the major ... strategies impacting the preparative and process chromatography market ... revenue and share analysis. , Full Copy ...
(Date:12/24/2014)... Long Island, New York (PRWEB) December 23, 2014 ... , and the Long Island Affiliate of ITRA Global, the ... economy’s slow but steady recovery. This is evidenced by ... and the strong stock market. Low energy costs have ... low. The only negative is the housing market remaining ...
(Date:12/24/2014)... -- China Biologic Products, Inc. (NASDAQ: CBPO, "China ... plasma-based biopharmaceutical company in China ... Taibang Biological Products Co. Ltd., has received Good ... and Drug Administration (the "CFDA") for its new ... the Company,s public filings, the CFDA inspected this ...
(Date:12/24/2014)... YORK , Dec. 23, 2014  NeuroLifeSciences announced ... mazindol in children with attention deficit/hyperactivity disorder published in ... . The paper, titled "Pilot Phase ... disorder" ( Konofal et al, Drug Des ... ) shows that mazindol might be an effective, ...
Breaking Biology Technology:Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3China Biologic Receives GMP Certification for New Coagulation Factor Facility 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 3Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3
... 26 Lexicon,Pharmaceuticals, Inc. (Nasdaq: LXRX ) today ... at the Piper Jaffray 19th Annual,Health Care Conference at ... November 28, 2007 at 8:30 a.m. Eastern Time., ... on Lexicon,s,corporate website at http://www.lexpharma.com . An archived ...
... Income up $1,036,024, or 89%, for the nine months ended September 30, ... ... China, Nov. 26 /Xinhua-PRNewswire-FirstCall/ -- China Kangtai,Cactus Bio-tech Inc. (OTC Bulletin Board: ... cactus-based,consumer products, filed its quarterly report on SEC Form 10QSB on November,19, ...
... 26 PRA International,(Nasdaq: PRAI ), a ... Chambers has been named its senior vice president ... to human resources that will,help PRA grow," said ... and employment law in addition to strong tactical ...
Cached Biology Technology:Lexicon Pharmaceuticals to Present at the Piper Jaffray 19th Annual Health Care Conference 2China Kangtai Cactus Biotech, Inc. Reports Third Quarter 2007 Financial Results 2China Kangtai Cactus Biotech, Inc. Reports Third Quarter 2007 Financial Results 3China Kangtai Cactus Biotech, Inc. Reports Third Quarter 2007 Financial Results 4Chambers Joins PRA International as Senior Vice President of Human Resources 2
... This kit #27295 has improved stability and convenience ... kit not only has overcome this problem but ... we have changed the formulation of HRP conjugated ... 1). By this change, the stability of the ...
Mouse monoclonal [BC-4] to Aggrecan xxPEN ( Abpromise for all tested applications). entrezGeneID: 176 SwissProtID: P16112...
... screening, low melting point agarose where separation ... recommended for separation of nucleic acids less ... products. Micro ABgarose is also suited to ... blotting techniques. At a 3% concentration, Micro ...
Rabbit polyclonal to Nck alpha ( Abpromise for all tested applications). entrezGeneID: 4690 SwissProtID: P16333...
Biology Products: