Navigation Links
New Swedish research hope for millions of sufferers

Todays issue of the scientific journal Science presents research on the genetic make-up and biology of the parasite Giardia lamblia that ultimately may lead to better diagnosis and treatment of the diarrhea disease giardiasis, which affects 200 million people every year. It may also bring an understanding of several vital biological processes in humans.

Giardia lamblia is an intestinal parasite that exists all over the world and causes diarrhea. Above all, it affects young individuals, and in the third world the infection is extremely common. At present roughly 200 million people are infected with Giardia; Sweden has 1,500 cases each year, with infection spreading at day-care centers and via polluted water. Recently the Norwegian city of Bergen experienced a major water-borne epidemic, with 1,300 people infected by the parasite. Young animals can also get Giardia infections, which entails major costs for agriculture. It is not known why Giardia makes people sick, nor why some people are more susceptible than others.

Todays issue of Science includes an article by Swedish and American researchers describing the genetic sequence and biology of Giardia lamblia and comparing it with other organisms. Among other things, the article shows that the parasite differs in several ways from other organisms when it comes to the copying and reading of DNA. The parasite also lacks several common signal proteins, but, on the other hand, it has many enzymes of the protein kinase and protein phosphate type whose functions are still unknown.

Research on the parasite will be radically changed, and new methods that were previously unusable can now be applied. This means that there is great potential for finding new medicines, vaccines, and diagnostic tools much more quickly and efficiently. This opens new paths for finding treatment for this severe disease, says Associate Professor Staffan Svrd, Uppsala University, co-author of the study being published.

Giardia is a remote relative of human beings, which is reflected in the fact that many basic processes occur in both cell types, but the analysis of the genome shows that the parasites processes are much more simply structured. This means that much more complicated processes in humans can be understood more readily.

Its easier to do a puzzle with 4 pieces compared with 40 pieces, and it shows us what pieces are most important in the human puzzle, explains Staffan Svrd.


Contact: Staffan Svrd
Uppsala University

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
3. Columbia research lifts major hurdle to gene therapy for cancer
4. Researchers find how protein allows insects to detect and respond to pheromones
5. Researchers Uncover Key Step In Manufacture of Memory Protein
6. Research advances quest for HIV-1 vaccine
7. Research on Worms Yields Clues on Aging
8. U of M researcher examines newly emerging deadly disease
9. NYU researchers simulate molecular biological clock
10. Researchers reveal the infectious impact of salmon farms on wild salmon
11. Researchers identify target for cancer drugs
Post Your Comments:
(Date:4/28/2016)... and BANGALORE, India , April 28, ... Systems, a product subsidiary of Infosys (NYSE: INFY ... announced a global partnership that will provide end ... use mobile banking and payment services.      (Logo: ... key innovation area for financial services, but it also plays ...
(Date:4/19/2016)... 2016 The new GEZE SecuLogic ... web-based "all-in-one" system solution for all door components. It ... the door interface with integration authorization management system, and ... The minimal dimensions of the access control and the ... installations offer considerable freedom of design with regard to ...
(Date:4/13/2016)... , April 13, 2016  IMPOWER physicians supporting Medicaid ... setting a new clinical standard in telehealth thanks to ... leveraging the higi platform, IMPOWER patients can routinely track ... and body mass index, and, when they opt in, ... convenient visit to a local retail location at no ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, ... of the Supplyframe Design Lab . Located in Pasadena, Calif., the Design ... of how hardware projects are designed, built and brought to market. , The ...
(Date:6/23/2016)... BEACH, Calif. , June 23, 2016  Blueprint ... new biological discoveries to the medical community, has closed ... co-founder Matthew Nunez . "We have ... us with the capital we need to meet our ... will essentially provide us the runway to complete validation ...
(Date:6/23/2016)... ... June 23, 2016 , ... Regulatory ... technical consulting, provides a free webinar on Performing Quality Investigations: Getting ... at 12pm CT at no charge. , Incomplete investigations are still a major ...
(Date:6/22/2016)... June 22, 2016 Cell Applications, Inc. ... them to produce up to one billion human ... within one week. These high-quality, consistent stem cells ... cells and spend more time doing meaningful, relevant ... proprietary, high-volume manufacturing process that produces affordable, reliable ...
Breaking Biology Technology: