Navigation Links
New NIH/NHGRI grants to harness nanoscale technologies to cut DNA sequencing costs
Date:9/14/2012

Grants of almost $19 million will help to develop technologies to dramatically reduce the cost of DNA sequencing, the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, announced today.

During the past decade, DNA sequencing costs have fallen dramatically (see www.genome.gov/sequencingcosts), fueled by tools, technologies and process improvements developed by genomics researchers. In 2004, NHGRI launched the Advanced DNA Sequencing Technology Program to accelerate improvements in DNA sequencing technologies. By 2009, the program had surpassed its initial goal of producing high-quality genome sequences of roughly 6 billion base pairs the amount of DNA found in humans and other mammals that receive roughly 3 billion base pairs from each of their parents for $100,000 each. Today, the cost of sequencing a human genome using these next-generation DNA sequencing technologies has dipped to just under $8,000.

Price is one hurdle in the way of widespread use of genomics in research and clinical care. Speed and accuracy are among other factors. The grants will attempt to address all of these challenges.

"We can now access data we could not dream of getting in 2004 when we started this program tens of thousands of human genome sequences have been generated," said Eric D. Green, M.D., Ph.D., NHGRI director. "And yet, the information we would truly like to get for understanding disease and, eventually, for treating patients, requires much better quality sequence data. That is the direction we would like to go with these grants."

The use of nanoscale devices for sequencing, reflected in many of these projects, is accelerating. To say that nanoscale devices function on a very small scale is an understatement. A human hair is 100,000 nanometers in diameter and a single strand of DNA is 2 nanometers in diameter.

"Several of the investigative teams will explore novel nanoscale sensing mo
'/>"/>

Contact: Omar McCrimmon
mccrimmono@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Scientist wins $3 million renewal of one of longest-running NIH grants to Scripps Research
2. Bay Area PV Consortium announces $7.5 million in grants to lower the cost of large-scale solar
3. Grants add to Northwestern-Qatar partnership
4. American Health Assistance Foundation announces grants to advance promising vision research
5. 6 NARSAD Young Investigator Grants awarded to CAMH
6. 2 UNC faculty receive Autism Centers of Excellence grants for new research
7. A new vision for harnessing data about life on Earth
8. Harnessing the Materials Genome Conference
9. Harnessing anticancer drugs for the future fight against influenza
10. Nanoscale scaffolds and stem cells show promise in cartilage repair
11. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... some hope: A new research report published in October ... , explains how scientists developed a synthetic version of ... development in human and mouse eggs similar to the ... during fertilization. , "We believe that the results of ... understanding of human fertilization by providing a precise answer ...
(Date:9/30/2014)... suite of perilous threats in today,s ocean. From ... change, fragile coral ecosystems are disappearing at unprecedented ... species of corals surrounding the island of Moorea ... their tropical environment: coral guard-crabs. New research from ... Station scientist Seabird McKeon and the museum,s predoctoral ...
(Date:9/29/2014)... Clostridium ramosum , coupled with a high-fat diet, may ... week in mBio , the online open-access journal of ... from the German Institute of Human Nutrition Potsdam-Rehbruecke in Nuthetal ... ramosum gained weight when fed a high-fat diet. Mice ... obese even when consuming a high-fat diet, and mice that ...
Breaking Biology News(10 mins):Synthetic sperm protein raises the chance for successful in vitro fertilization 2Smithsonian scientists discover coral's best defender against an army of sea stars 2Gut bacteria promote obesity in mice 2
... food safety and traceability will be showcased at a ... The Food Integrity and Traceability Conference will take place ... leading scientists, food standards regulators and agri-food producers from ... Institute for Global Food Security and from across the ...
... BRCA2 gene have a worse prognosis and lower survival rates ... This is the main conclusion to come out of a ... Oncology , in which David Olmos, Head of the Prostate ... National Cancer Research Centre (CNIO), has taken part in, along ...
... making the disease difficult to study. However, K9 bone ... the disease, and over 10,000 canine patients develop the ... Cancer Center and the Colorado State University Flint Animal ... used easily available K9 osteosarcoma samples to discover a ...
Cached Biology News:International conference will put agri-food supply chain under the microscope 2First genetic factor in prostate cancer prognosis identified 2AACR news: K9 osteosarcoma samples identify drivers of metastasis in pediatric bone cancer 2
(Date:10/2/2014)... 2014 Permian Plastics, http://www.permianplastics.com ... Louis, Missouri, area on October 24th, 1994. Since ... plastic injection molder in the Midwest. The company operates ... supplier to many Fortune 500 clients. , Permian Plastics ... of the way, from concept to completion, going the ...
(Date:10/2/2014)... 02, 2014 The National Institutes ... (LLNL) a grant today to develop an electrode ... understand how the brain works through unprecedented resolution ... of NIH's efforts to support President Obama's BRAIN ... new research effort to revolutionize our understanding of ...
(Date:10/2/2014)... 2 de octubre de 2014 Laborie Medical ... Ontario , ha completado la adquisición de Unisensor ... Unisensor tiene su sede central sita en Wiesendangen, Suiza, ... Portsmouth, New Hampshire . Unisensor está ... de alta resolución para evaluar la presión y valores ...
(Date:10/2/2014)... WALTHAM, Mass. , Oct. 2, 2014 /PRNewswire/ ... and Drug Administration has granted Fast Track designation ... for the treatment of sickle cell disease.  NKTT120 ... iNKT cells, a regulatory T cell that has ... organ damage in preclinical models of sickle cell ...
Breaking Biology Technology:Permian Plastics LLC Celebrates 20 Years As Leading Manufacturer of Plastic Molds 2NIH taps Lawrence Livermore to Develop Sophisticated Electrode Array System to Monitor Brain Activity 2NIH taps Lawrence Livermore to Develop Sophisticated Electrode Array System to Monitor Brain Activity 3NIH taps Lawrence Livermore to Develop Sophisticated Electrode Array System to Monitor Brain Activity 4LABORIE adquiere Unisensor AG y Unisensor USA, Inc. 2FDA Grants Fast Track Designation to NKT Therapeutics' NKTT120 for the Treatment of Sickle Cell Disease 2
... ANTONY, France, July 10 , - 1st Half-Year Sales Up 16%, - Revision Upwards of 2008 Sales Growth Guidance: (greater than or equal,to)12%, EUR millions ... 07/06 2008 08/07 ... ... Europe (1) 20.5 72 23.2 72 13 26.8 71 ...
... July 10 Today,s Pharmaceutical Research,and ... to end the practice,of providing non-educational ... toward,enhancing the value of the physician/industry ... CMR Institute, a leading non-profit,organization dedicated ...
... July 10 Quest Diagnostics,Incorporated (NYSE: DGX ), ... announced today that its second-quarter,2008 results will be made ... that it will hold its quarterly conference call with ... on that day., The public may access the ...
Cached Biology Technology:Stallergenes: Q2 2008 Sales up 18% Revision Upwards of 2008 Sales Growth 2CMR Institute: Education Key to Physician/Representative Relationship 2Quest Diagnostics to Release Second Quarter 2008 Financial Results 2
Human SEAP ORF, provided in a pORF plasmid. pORF is an expression plasmid selectable with Ampicillin....
... of purified RNA samples., , This product ... aqueous RNA samples that have been pre-purified ... silica, oligo dT etc or other kits. ... necessary components for the stabilization of nanogram ...
... These 2800mL wide mouth PYREX Fernbach-style culture ... center of the flask bottom to achieve ... triple baffled flasks have a Delong-style 38mm ... steel closures. For plastic closures see Nos. ...
... template is designed to allow neomycin/kanamycin selection ... FRT-PGK-gb2-neo-FRT template encodes the neomycin/kanamycin resistance gene ... expression of kanamycin resistance in E.coli ... expression of neomycin resistance in mammalian cells. ...
Biology Products: