Navigation Links
New Keck award spurs research for low-cost, mass measurements
Date:8/24/2011

/p>

Nevertheless, conventional mass spectrometry has limits. The technique is slow, bulky and expensive. Further, elaborate sample preparation is involved and the method is not capable of providing real-time information about molecular binding affinity. Affinity information is often critical for understanding biological activities such as antigen-antibody and drug-target interactions as well as a variety of molecular functions.

The new approach provides a simple, fast and miniaturized means of conducting molecular mass measurements. Unlike conventional mass spectrometry, Tao's approach aims at detecting the binding of molecules in their native environment, including under aqueous conditions, allowing not only mass measurement but also functional analysis. (more)

The mechanical oscillators are self-assembled on a chip surface. This bottom-up approach permits rapid, accurate fabrication of these tiny structures, measuring just a few nanometers in size. The method also permits precise control over the oscillators' resonant frequencies, at the same time allowing simple detection of the oscillations with high throughput.

Tao's technique makes use of two quantities, known in advance with precision: each oscillator's mass and the spring constanta measure of the connecting molecule's elasticity. The mass and spring constant of the oscillators are precisely defined, but they also can be tuned. This enables the resonant frequency of the oscillator to be adjusted from gigahertz to terahertz frequencies.

This frequency range is important, because it spans a region of the electromagnetic spectrum falling between infrared and microwave. As Tao notes, such frequencies are too low for conventional optical measurements and too high for typical electronic detections. To overcome these detection limits, the group will use specialized techniques.

A property known as surface plasmon resonance will be used for optical detection of the mol
'/>"/>

Contact: Joseph Caspermeyer
joseph.caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. NIH doles out $3M in new innovator awards to 2 UC San Diego faculty
2. Wistar Institute researcher receives New Innovator award from NIH
3. Stevens awarded $1M for advanced biofuels research
4. NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves
5. L-1 Identity Solutions Awarded New Massachusetts RMV Drivers License Contract Valued at an Estimated $32 Million
6. Entomological Society of America names 2008 award winners
7. 8 National Medals of Science awardees to be honored at gala, then the White House
8. BIO-keys(R) Law Enforcement Group Awarded $700,000 in New Contracts
9. Broad Institute awarded major grant to bolster epigenomics research
10. Entertainment Software Association Foundation awards grant to FAS for immune attack
11. Audience Selected as Silver Winner in This Years Wall Street Journal Technology Innovation Awards and Winner of the Semiconductors Category
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Keck award spurs research for low-cost, mass measurements  
(Date:8/21/2014)... has successfully replicated one of the crucial steps in ... sunlight which could manufacture hydrogen as a fuel. , ... an exciting prospect to use them to create hydrogen, ... Hingorani, from the ARC Centre of Excellence for Translational ... Hydrogen offers potential as a zero-carbon replacement for petroleum ...
(Date:8/21/2014)... involves the pancreas digesting itself resulting in severe abdominal ... UK around 20,000 patients are diagnosed with the disease ... and treatment is restricted to intravenous fluid and nutritional ... of Life Sciences, who led the research, said "The ... gall stones and excessive alcohol intake combined with a ...
(Date:8/20/2014)... study of 158 pregnant teenagers in Rochester, NY, nearly ... consumption of ice, cornstarch, vacuum dust, baby powder and ... study. , Moreover, such teens had significantly lower iron ... nonfood substances. , Pregnant teens, regardless of pica, are ... to iron deficiency and anemia. Low iron in pregnant ...
Breaking Biology News(10 mins):Water and sunlight the formula for sustainable fuel 2Insulin offers new hope for the treatment of acute pancreatitis 2Pica in pregnant teens linked to low iron 2
... studying fuels from biomass for years. Now, with growing ... biofuels are fast becoming part of a fuel revolution ... Ethanol blends are already available at some gas stations. ... on the volume of ethanol produced. Sources of biomass ...
... Katrina on soil quality and agriculture? How can soil help ... biofuels help make America energy independent? These topics and others ... Meetings of the American Society of Agronomy (ASA), Crop Science ... (SSSA) Nov. 4-8, 2007 at the Ernest N. Morial Convention ...
... in German . , Fossil remains of ... about their cognitive skills or give us details of ... team at the Max Planck Institute for Evolutionary Anthropology ... they have made some new and astonishing discoveries. Just ...
Cached Biology News:The race for biofuels driving alternative sources of biomass 2Food and environmental sustainability focus of ASA-CSSA-SSSA Annual Meetings 2Red hair and freckles... 2
(Date:8/21/2014)... of last week RENU 28, the world's first and only ... purchase in Australia and New Zealand, and the response has ... if you think about the definition of aging, it's really ... your body. If you think about the definition of anti-aging, ... RENU 28 does is it works with these tiny little ...
(Date:8/20/2014)... lessons often have it that American Indians largely were ... pox, influenza and tuberculosis brought to the New World ... about 20 million people lived in the Americas shortly ... were killed by European diseases., But new research led ... and Johannes Krause of the University of Tubingen in ...
(Date:8/20/2014)... 20, 2014 High performance computing ... the most complete climate and Earth system model ... change issues. , Eight national laboratories, including ... National Center for Atmospheric Research, four academic institutions ... Other participating national laboratories include Argonne, Brookhaven, Lawrence ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 The ... is being held on October 29-30 in San Francisco, ... industry, academic and government researchers and clinicians focused on ... space. , In the twelve years since the ... therapies have been introduced with pharmacogenetic information in the ...
Breaking Biology Technology:RENU 28 Skin Care Now Available in Australia and New Zealand 2Unusual discovery leads to fascinating tuberculosis theory 2Unusual discovery leads to fascinating tuberculosis theory 3New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 36th Annual Personalized and Precision Medicine Conference Bringing Together Thought Leaders to Discuss Clinical Implementation, Dx Reimbursement, Big Data, and Sequencing 2
... FRANCISCO , Jan. 13 Today, endpoint ( ... users to design and deploy clinical trial IRT systems in ... Leveraging a background of more than 12 years designing Integrated ... designed PULSE to balance speed of deployment with flawless quality. ...
... , BIRMINGHAM, Ala. , ... BCRX ) today announced that its partner, Shionogi & Co., ... peramivir to treat patients with influenza in Japan . ... RAPIACTA in Japan , pending the product,s National Health ...
... , , , , ... the Brazilian Sugarcane,Industry Association (UNICA), the federal government,s decision to ... must be limited to the,established 90-day period. , ... understandable,but the move must be limited to the 90-day period ...
Cached Biology Technology:endpoint Introduces First Fully Configurable IRT System 2BioCryst's Partner Shionogi Receives Marketing & Manufacturing Approval For Peramivir in Japan 2BioCryst's Partner Shionogi Receives Marketing & Manufacturing Approval For Peramivir in Japan 3BioCryst's Partner Shionogi Receives Marketing & Manufacturing Approval For Peramivir in Japan 4Ethanol Blend Reduction in Brazil 'Makes Sense' Provided 90-Day Deadline is Respected, Says Brazilian Sugarcane Industry Association 2Ethanol Blend Reduction in Brazil 'Makes Sense' Provided 90-Day Deadline is Respected, Says Brazilian Sugarcane Industry Association 3
PC based system for superior chemifluorescent, chemiluminescent, fluorescent and colorimetric, microarray and microscope imaging and analysis....
Request Info...
... Well Plate Sterile with ... range of 384-well plates ... screening and research. These ... and are suitable for ...
HLA-DRbeta (DA2)...
Biology Products: