Navigation Links
New, less invasive genetic test greatly improves pregnancy rates in older women with poor prognosis
Date:6/29/2009

ing embryo than other alternatives, such as day-three biopsy, which take place during conventional screening strategies involving the use of the FISH technique. The removal of the polar bodies does not adversely affect the subsequent development of the embryo. Additionally, the results obtained after CGH analysis of polar bodies are not affected by the presence of chromosomal mosaicism (the presence of two populations of cells with different genotypes) and therefore may be more accurate than conventional methods based upon screening of cells removed from embryos.

The scientists examined 400 fertilised eggs generated by women with a very poor reproductive history and with an average age of 42 who were undergoing IVF because of being unable to conceive or to maintain a pregnancy. They found that more than half of all the eggs produced by these women had chromosomal abnormalities, and therefore the resulting embryos were also chromosomally abnormal. Some of the women had a tendency to produce eggs that were extremely abnormal and carried multiple chromosome errors. This could explain the poor reproductive history of these women, the scientists say.

"But where we could find fertilised eggs free of chromosomal abnormalities, the resulting embryos were also normal and their transfer to the mother led to pregnancies," said Dr. Fragouli. "Results suggest that the use of this technique will improve IVF success rates for poor prognosis patients. It is also likely to achieve a reduction in congenital abnormalities such as Down's syndrome, as well as a reduction in the frequency of spontaneous miscarriage."

The incidence of chromosomal abnormalities in human eggs is closely related to maternal age, and can affect more than 60% of all eggs in women over 40 years of age. Being able to select the right egg can not only lead to more successful IVF, but also enhance the use of single embryo transfer, especially in countries where embryo testing is forbidde
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society for Human Reproduction and Embryology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Invasive Australian jellyfish sighted in Gulf of Mexico in summer 2007
2. New chemically-sensitive MRI scan may bypass some invasive diagnostic tests in next decade
3. U of MN researchers discover noninvasive diagnostic tool for brain diseases
4. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
5. Minimally invasive heart surgery research wins NIH award
6. Smithsonian identifies invasive crab species in Panama Canal expansion area
7. Smithsonian identifies invasive crab species in Panama Canal expansion area
8. Book on weeds and invasive plants discusses how to manage them using ecological approaches
9. A new baseline of invasive plants in Isabela
10. Team of scientists develops non-invasive method to track nerve-cell development in live human brain
11. Relationship between invasive plants, fire subject of new report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Salk Institute for Biological Studies, BGI, and other ... and reliability of the existing targeted gene correction ... which could significantly increased gene-correction efficiency in human ... online in Cell Stell Cell provides ... therapy. , The combination of stem cells and ...
(Date:7/11/2014)... July 11, 2014 Researchers have pioneered ... images. The new technology, called Virtual Finger, allows ... structures like neurons and synapses using the flat ... technology makes 3D imaging studies orders of magnitude ... an unprecedented level across many areas of experimental ...
(Date:7/11/2014)... the normal circumstances, astrocytes participate in normal ... and exhibit therapeutic and repairing effects on ... have found that nerve cells differentiated from ... reduced viability, which produces influences on subsequent ... General Hospital, Hebei United University, China demonstrated ...
Breaking Biology News(10 mins):A new genome editing method brings the possibility of gene therapies closer to reality 2Virtual finger enables scientists to navigate and analyze complex 3D images 2
... COLUMBUS, Ohio From the paleolithic diet to the raw ... they believe our ancient ancestors ate. But some of these ... new book on the evolution of the use of food and ... can learn from what our ancestors ate, many of our more ...
... E. coli food poisoning outbreaks developed more ... trials because of lack of commercial interest. University of ... neutralises the toxin produced by E. coli , which ... The team of scientists Dr Adrienne Paton, Associate Professor ...
... to phase out nuclear power by 2022 has reopened an ... Japan, which is still coming to terms with events at ... the SETAC journal Environmental Toxicology and Chemistry adds ... using research from the Chernobyl disaster. The issue ...
Cached Biology News:An 'all natural' diet? There's no such thing 2An 'all natural' diet? There's no such thing 3Potential treatment for deadly E. coli disease 2
(Date:7/10/2014)... , July 10, 2014  Franciscan ... use of capnography for respiratory monitoring outside ... of healthcare leaders in embracing state-of-the-art patient ... effectively patients are breathing and can alert ... By measuring the amount of carbon dioxide ...
(Date:7/10/2014)... -- Research and Markets ( http://www.researchandmarkets.com/research/s3bqj2/photonic ) has ... Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... traces its roots in the latter half of ... went unexplored and unfulfilled for several decades owing ...
(Date:7/10/2014)... D.C., June 17, 2014 Using microscopic polymer ... specific gases, researchers at MIT,s Quantum Photonics Laboratory ... levels in the parts-per-billion range. Optical sensors are ... their high signal-to-noise ratio, compact, lightweight nature, and ... gas sensors had been developed before, the MIT ...
(Date:7/10/2014)... lithium-ion batteries that power our laptops and electric vehicles ... single charge with the help of a sponge-like silicon ... replace the graphite traditionally used in one of the ... the energy storage capacity of graphite. A paper describing ... published today in Nature Communications . , "Silicon ...
Breaking Biology Technology:Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2Swell new sensors 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3
... Dimensions , a Wisconsin data management firm, announced last ... the New York metro area by partnering with MailSurity ... company that develops paper scanning and data recognition technology, ... its software to process forms. , ,Parascript's software is ...
... rude noise somebody makes in a meeting after too ... population also knows that Enterprise Resource Planning isnt some ... single check to a vendor. , ,Im not out ... is apparently less obvious is that ERP systems dont ...
... provider of rich-media systems and software, is deploying its ... announced. , ,Sonic Foundry and media services provider ... Connect's new Virtual Law Viewer system for the ... MediaSite presentation recorders with the BxVideo RMXPRES hosting services, ...
Cached Biology Technology:Steering a project portfolio takes more than expensive software 2Steering a project portfolio takes more than expensive software 3Streaming video could make courtrooms into Internet conference calls 2
... product contains 5 ml Dynabeads Tosylactivated (4.5 ... (tosyl) reactive groups. For coupling of antibodies ... on initial coupling with covalent binding of ... sulphydryll groups (SH)) occurringovernight. Coupling reactions can ...
Carrier-Free Recombinant Human Flt-3/Flk-2 Ligand (Flt3/Flk2 Ligand, Flt3L, Flt3-L, Flk2L, Flk2-L) 100 ug...
... II inhibitor (IC50 = 59.2 M). ... H 32 O 13 MolWeight: ... RT CAS: ... Soluble to 100 mM in DMSO ...
NAP-2 (5C7)...
Biology Products: