Navigation Links
New, less invasive genetic test greatly improves pregnancy rates in older women with poor prognosis
Date:6/29/2009

ing embryo than other alternatives, such as day-three biopsy, which take place during conventional screening strategies involving the use of the FISH technique. The removal of the polar bodies does not adversely affect the subsequent development of the embryo. Additionally, the results obtained after CGH analysis of polar bodies are not affected by the presence of chromosomal mosaicism (the presence of two populations of cells with different genotypes) and therefore may be more accurate than conventional methods based upon screening of cells removed from embryos.

The scientists examined 400 fertilised eggs generated by women with a very poor reproductive history and with an average age of 42 who were undergoing IVF because of being unable to conceive or to maintain a pregnancy. They found that more than half of all the eggs produced by these women had chromosomal abnormalities, and therefore the resulting embryos were also chromosomally abnormal. Some of the women had a tendency to produce eggs that were extremely abnormal and carried multiple chromosome errors. This could explain the poor reproductive history of these women, the scientists say.

"But where we could find fertilised eggs free of chromosomal abnormalities, the resulting embryos were also normal and their transfer to the mother led to pregnancies," said Dr. Fragouli. "Results suggest that the use of this technique will improve IVF success rates for poor prognosis patients. It is also likely to achieve a reduction in congenital abnormalities such as Down's syndrome, as well as a reduction in the frequency of spontaneous miscarriage."

The incidence of chromosomal abnormalities in human eggs is closely related to maternal age, and can affect more than 60% of all eggs in women over 40 years of age. Being able to select the right egg can not only lead to more successful IVF, but also enhance the use of single embryo transfer, especially in countries where embryo testing is forbidde
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society for Human Reproduction and Embryology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Invasive Australian jellyfish sighted in Gulf of Mexico in summer 2007
2. New chemically-sensitive MRI scan may bypass some invasive diagnostic tests in next decade
3. U of MN researchers discover noninvasive diagnostic tool for brain diseases
4. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
5. Minimally invasive heart surgery research wins NIH award
6. Smithsonian identifies invasive crab species in Panama Canal expansion area
7. Smithsonian identifies invasive crab species in Panama Canal expansion area
8. Book on weeds and invasive plants discusses how to manage them using ecological approaches
9. A new baseline of invasive plants in Isabela
10. Team of scientists develops non-invasive method to track nerve-cell development in live human brain
11. Relationship between invasive plants, fire subject of new report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/29/2014)... ago when the supercontinent of Pangea was starting to break ... different kinds of reptiles called phytosaurs and rauisuchids were at ... believed the two top predators didn,t interact much as the ... the land. But those ideas are changing, thanks largely to ... published online in September in the German journal ...
(Date:9/29/2014)... has significant anti-tumour activity in patients with advanced ... disease has progressed after chemotherapy, according to phase ... in Madrid, Spain. , "Reports of lung ... interest because these mutations may be associated with ... lead author Dr David Planchard, pulmonary oncologist at ...
(Date:9/29/2014)... 2014 NXT-ID, Inc. (Nasdaq: NXTD ... authentication company focused on the growing mobile commerce market, ... been named the Company,s Vice-President and Chief Financial Officer ... as Chief Financial Officer. Mr. Pereira will continue to ... a Director. Mr. Miceli, age 56, has ...
Breaking Biology News(10 mins):Tooth buried in bone shows prehistoric predators tangled across land, sea 2Promising results shown with targeted approaches in subsets of non-small cell lung cancer 2Promising results shown with targeted approaches in subsets of non-small cell lung cancer 3NXT-ID, Inc. Names Vice-President and Chief Financial Officer 2NXT-ID, Inc. Names Vice-President and Chief Financial Officer 3
... Chalmers University of Technology have built a very simple ... directions, even though the antenna is smaller than the ... online journal Nature Communications this week ... very low concentrations of gases or biomolecules. A ...
... 2011 The Translational Genomics Research Institute (TGen) is ... $3.5 million grant from Susan G. Komen for the ... form of this cancer that disproportionately affects African-Americans. ... of physicians and scientists called Promise Grants, multi-million dollar, ...
... of Utah researchers have discovered a new class of compounds ... and inhibit it from infecting cells an early step ... virus. Development and laboratory testing of the potential new ... a study set for online publication by Friday in the ...
Cached Biology News:Bimetallic nanoantenna separates colors of light 2TGen breast cancer research benefits from $3.5 million Komen award 2TGen breast cancer research benefits from $3.5 million Komen award 3Targeting HIV's sugar coating 2Targeting HIV's sugar coating 3
(Date:9/30/2014)... 2014 The custom stainless steel fabrication ... Show 2014. The Boston Area Chapter of ISPE (International ... day-long event for Wed., Oct. 1 at Gillette Stadium ... the largest in ISPE Boston’s long history, with more ... attendees expected. , HOLLOWAY AMERICA President David Simpson ...
(Date:9/30/2014)... Lyme Research Alliance (LRA), the ... at universities, today announced the awarding of seven grants ... and cure for Lyme and other tick-borne diseases. ... in its history—over 20 grant proposals—a 100 percent increase ... to receive so many solid applications from talented scientists ...
(Date:9/30/2014)... 30, 2014 SoundConnect, ... company is dedicated to supporting business communication solutions, ... Julie Power, a carrier services specialist ... solutions stays connected and productive at all times. ... movement of businesses to cloud communications services. ...
(Date:9/30/2014)... September 30, 2014 Rainbow Scientific, ... research products, recently opened an online store to ... culture product lines developed and manufactured by Biological ... store include Biological Industries’ Nutristem® serum-free, xeno-free reagents ... embryonic stem cell (hESC) culture. , The ...
Breaking Biology Technology:HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 2HOLLOWAY AMERICA to Exhibit at ISPE Boston Product Show 2014 3Lyme Research Alliance Awards Nearly $600,000 in New Grants 2Lyme Research Alliance Awards Nearly $600,000 in New Grants 3Lyme Research Alliance Awards Nearly $600,000 in New Grants 4SoundConnect Expands Carrier Services Division 2Rainbow Scientific, Inc. opens online store for state-of-the-art stem cell culture and cytogenetic reagents 2
... Therapeutics,Inc. (Nasdaq: IMRX ), a biopharmaceutical company ... financial,results for the first quarter ended March 31, ... Highlights:, -- Entered into agreement with Abbott ... obligation under non-recourse promissory note issued in connection ...
... Spain, May 15 Forest,Laboratories, Inc. (NYSE: ... a webcast to discuss aclidinium bromide clinical and ... Annual Congress.,The webcast, which will include a slide ... May 21, 2008 at 9:30am New York time, ...
... Care Advisory Panel reacts to CMS final rule; ... identifies challenges, recommends ... Industries, Inc. and,the International Expert Wound Care Advisory ... to Improve Pressure,Ulcer Prevention and Treatment: Implications of ...
Cached Biology Technology:ImaRx Therapeutics Reports First Quarter Ended 2008 Financial Results 2ImaRx Therapeutics Reports First Quarter Ended 2008 Financial Results 3ImaRx Therapeutics Reports First Quarter Ended 2008 Financial Results 4ImaRx Therapeutics Reports First Quarter Ended 2008 Financial Results 5ImaRx Therapeutics Reports First Quarter Ended 2008 Financial Results 6ImaRx Therapeutics Reports First Quarter Ended 2008 Financial Results 7Forest Laboratories, Inc. and Laboratorios Almirall, S.A. to Host Webcast to Discuss Aclidinium Bromide Data Presentations at the American Thoracic Society Annual Congress 2International Wound Care Experts, Medline Announce Pressure Ulcer Prevention Consensus Paper 2International Wound Care Experts, Medline Announce Pressure Ulcer Prevention Consensus Paper 3
Request Info...
Request Info...
... Nebulizers are available in two product models - ... two models is that the 6000AT+ includes a ... drier aerosol for improved detection limits and reduced ... a range of elements by 10-40 times. Note ...
...
Biology Products: