Navigation Links
New, 'designer' fiber may help address fiber intolerance and ease IBS symptoms
Date:1/16/2014

(CHICAGO) A newly-developed, "designer" dietary fiber with an added potential prebiotic effect may eliminate the side effects of current treatment for Irritable Bowel Syndrome (IBS) which affects 10-20 percent of the population, disproportionately women.

The collaboration between a gastroenterologist at Rush and a carbohydrate chemist at Purdue University led to the development of the new product, a natural starch derived from a mixture of seaweed and starch in which the release of starch fiber in the gastrointestinal tract can be delayed, slowed and controlled to occur in the colon, rather than in the stomach and upper intestine.

"This new product prevents the discomfort and bloating associated with current fiber therapies, while getting our new fiber into the colon and specifically distal colon where traditional fiber products typically do not reach and where many diseases of colon-like cancers develop," said Dr. Ece Mutlu, principal investigator the phase II trial that will begin at Rush in January 2014. "This can provide an effective treatment for IBS, decrease the risk of colon cancer and possibly inflammatory diseases like colitis," she added. The study seeks 200 people who have been diagnosed with IBS and constipation.

In an earlier Phase I study with 60 patients suffering from constipation, the newly designed fiber was shown to be safe, better tolerated and with fewer side effects than currently available fiber treatments for constipation, and it had a positive effect on intestinal microbiota composition by promoting the growth of "healthy" bacteria in the colon.

"We wanted to create a fiber with a slow rate of fermentation to avoid rapid expansion of the gut and thus decrease the likelihood of common side effects of conventionally used fibers like bloating," said Dr. Ali Keshavarzian, professor and director of gastroenterology at Rush.

The fiber is also designed to produce a high level of a short chain
'/>"/>

Contact: Nancy DiFiore
nancy_difiore@rush.edu
312-942-5159
Rush University Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. African scientist, designer partner to fashion anti-malaria garment that wards off bugs
2. University of Albertas designer compounds inhibit prion infection
3. Biologists engineer algae to make complex anti-cancer designer drug
4. Designer bacteria may lead to better vaccines
5. Finland to lead the way as a designer of cellulose-based products
6. Molecular biology: Designer of protein factories exposed
7. Designer piercings: New membrane pores with DNA nanotechnology
8. Killer silk: Making silk fibers that kill anthrax and other microbes in minutes
9. Nanocrystal-coated fibers might reduce wasted energy
10. New research underscores the health benefits of fibers, including bone health
11. Inexpensive, abundant starch fibers could lead to ouchless bandages
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... -- Valencell, a leader in performance biometric data sensor technology, ... its licensees for highly accurate, clinically validated biometric technology. ... from fitness and health sectors, but first responders/military and ... only as useful as the biometric data it delivers. ... long-term mass consumer adoption of wearable products," said Dr. ...
(Date:12/5/2014)... 2014 Increased emphasis on product quality, ... testing and inspection technologies. The convergence of industries ... range of innovative test solutions. This trend is ... which is generally more inclined towards communication, media ... strategies of test equipment vendors will cater to ...
(Date:11/21/2014)... November 18, 2014 According to ... by Systems (Video, RFID, Access Control, Intrusion Detection, Parking ... Banks, Government), Component Service Geography - Global Forecasts to ... is projected to be around $25 Billion in 2014 ... growing at a CAGR of 8.69%. Browse ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
... to the national Centers for Disease Control and Prevention, 5 to ... with it. About 36,000 people will die. , But among health ... flu pandemic, such as a human strain of avian flu. And ... health crisis will come but when. Are we prepared? In a ...
... is believing, especially in medicine. From magnetic resonance ... of the body’s tissues and organs have become ... and make recommendations for effective treatment. ... Kent State University will provide doctors with a ...
... The skin’s ability to replace the tissue it sloughs off ... from Harvard Medical School published in the May 4 issue ... process not only for skin, but for many epithelial tissues ... epithelial stem cells turns out to be the p63 gene, ...
Cached Biology News:US control strategies may make flu epidemics worse, UCLA study shows 2Novel system developed to turn data into real-time, interactive 3-D images 2Master regulatory gene of epithelial stem cells identified 2
(Date:12/19/2014)... FL (PRWEB) December 18, 2014 ... the nation’s leading specialty pharmacies, has an expanded ... as clinical pharmacy consultants for prescriber offices in ... expertise. , “We have a variety of ... For example, those specializing in hepatitis C help ...
(Date:12/19/2014)... MA (PRWEB) December 18, 2014 Reports ... in the United States suffer from one or more ... asthma, or cancer. Medication can address some of these ... daily activities that many sufferers face. While implanted nerve ... and stimulate the whole nerve, which can induce side ...
(Date:12/19/2014)... 18, 2014 With only 2 weeks ... special on Sartorius Biohit products . The product specials ... Picus Electronic Pipette Trade-in Program, and free pipette tips. ... officers around the world. They are ideal for lab ... include:, ,     Full volume range of 0.1 ...
(Date:12/19/2014)... -- Relmada Therapeutics, Inc. (OTCQB: RLMD), a clinical-stage company ... announced the results of its annual general meeting of ... year in Relmada,s history and it set the stage ... Sergio Traversa , chief executive officer of Relmada. "Over ... human resource and clinical development objectives that position Relmada ...
Breaking Biology Technology:BioPlus Specialty Pharmacy Expands ‘Regional Pharmaceutical Care Liaison’ Team 2BioPlus Specialty Pharmacy Expands ‘Regional Pharmaceutical Care Liaison’ Team 3Draper Wins GSK Funding for Smaller, Smarter Implantable Devices 2Major Pipette Distributor Pipette.com Announces Sartorius Year End Specials 2Relmada Therapeutics Announces Results of Annual Shareholders Meeting 2
... Recommends ,Do Not Vote, For Any of ... Shareholders of Biovail,Corporation (NYSE: BVF )(TSX: BVF) said today ... sharply criticized the incumbent board and,recommended ,Do Not Vote, for ... vote FOR two of the Concerned Shareholders,nominees, Joseph J. Krivulka ...
... Germany is on the,cutting edge in biotechnology R&D ... Companies located in Germany are poised to,profit from the ... expert panel, at the BIO International Convention (BIO 2008),in ... co-chaired the,panel along with the CEO of a major ...
... Part Of Georgetown University Hospital Arsenal Against ... ... Sciences (OTC,Bulletin Board: DSCI), a provider of advanced wound care products,announced ... Leptospermum Honey, has been used by clinicians at Georgetown,University Hospital,s Wound ...
Cached Biology Technology:Biovail Concerned Shareholders Welcome Glass Lewis Evaluation 2Biovail Concerned Shareholders Welcome Glass Lewis Evaluation 3BIO 2008: Germany on Cutting Edge in Biomanufacturing 2Derma Sciences MEDIHONEY(TM) Helps to Save Patient's Limb 2Derma Sciences MEDIHONEY(TM) Helps to Save Patient's Limb 3Derma Sciences MEDIHONEY(TM) Helps to Save Patient's Limb 4
Human plasmacytoid dendritic cells, BDCA-4+, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Dendritic Cells and EPCs...
Umbilical cord blood basophils, For immunohistochemistry (IHC)...
Human peripheral blood CD8+ T cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood PBMC and T Cells...
Umbilical cord blood CD4+ T cells, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood MNCs and T Cells...
Biology Products: