Navigation Links
New $11 million center to speed production of new compounds for drug discovery
Date:10/20/2008

l in size, however, such small molecules can make a big impact," he said.

Many existing drugs share similar molecular structures. Future advances in drug discovery and basic biomedical research both depend on the ability to more efficiently synthesize new compounds with significantly different molecular structures.

Working with Kozmin to establish the center were four University of Chicago colleagues: Hisashi Yamamoto, the Arthur Holly Compton Distinguished Service Professor in Chemistry; Viresh Rawal, Professor in Chemistry; Milan Mrksich, Professor in Chemistry; and Stephen Kron, Associate Professor in Molecular Genetics and Cell Biology.

Collaborating from Northwestern University is Karl Scheidt, the Irving M. Klotz Research Professor in Chemistry; and from the University of Illinois at Chicago are Vladimir Gevorgyan, Professor of Chemistry; and Jie Liang, Professor of Bioengineering.

"Each of these groups has expertise in different areas of organic chemistry," Kozmin said. "The idea is to combine this intellectual effort in order to produce these new molecules much more efficiently than anything that has been done before."

Organic chemists traditionally have collaborated with biologists while competing with other members of their own discipline who work on the same problem. "Here the idea is different," Kozmin said. "We would like to address a problem, but we would like to see how each of us can help each other in addressing that problem."

Supporting Kozmin's efforts to land the new NIH center in Chicago were Donald Levy, Vice President for Research and for National Laboratories; Robert Fefferman, Dean of the Physical Sciences Division; and Michael Hopkins, Professor and Chairman of the Chemistry Department.

"The National Institutes of Health this year funded five centers nationwide for chemical methodology and library development, four of which were renewals for existing centers. It's a great tribu
'/>"/>

Contact: Steve Koppes
skoppes@uchicago.edu
773-702-8366
University of Chicago
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Missouri Botanical Garden mounts milestone 6 millionth herbarium specimen
2. FSU researchers discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
3. L-1 Identity Solutions Awarded New Massachusetts RMV Drivers License Contract Valued at an Estimated $32 Million
4. L-1 Identity Solutions Receives $5.9 Million Drivers License Contract Expansion from the State of Mississippi
5. NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves
6. £2 million study to reveal workings of dementia genes
7. Almost 7 million pregnant in sub-Saharan Africa infected with hookworms; at risk of anaemia
8. CCNY receives $5 million NSF grant to establish center for nanostructure applications
9. Burnham researcher awarded $8 million grant
10. NIEHS invests $21.25 million to find environmental causes of Parkinsons disease
11. Cornell gets $10 million NSF grant to establish new sustainability institute
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New $11 million center to speed production of new compounds for drug discovery
(Date:9/19/2014)... shows that legume plants regulate their symbiotic relationship ... are transmitted through the plant structure from leaves ... bacteria-holding nodules in the roots. This collaborative study ... for Basic Biology, the Graduate University for Advanced ... Resource Science in Japan. , Legumes, an ...
(Date:9/18/2014)... September 18, 2014 New research into the Crimean-Congo ... a severe hemorrhagic disease in humans similar to that ... for CCHFV infection. This discovery has the potential to ... pathogen. , The research, reported in a ... and conducted by scientists at the Texas Biomedical ...
(Date:9/18/2014)... foliage season that prompts millions of Americans to undertake jaunts ... possibly last a little longer within a century, according to ... in some areas of the United States as summer temperatures ... the journal Global Ecology and Biogeography . For instance, ... the state tree of New Hampshire could change color ...
Breaking Biology News(10 mins):For legume plants, a new route from shoot to root 2Research milestone in CCHF virus could help identify new treatments 2Fall foliage season may be later, but longer on warmer Earth 2Fall foliage season may be later, but longer on warmer Earth 3Fall foliage season may be later, but longer on warmer Earth 4
... of Physics World is devoted to animal physics, ... skaters effortlessly skip across water leaving nothing but a small ... current understanding of the mechanisms adopted by the pond skater ... a mathematics graduate from the Massachusetts Institute of Technology spent ...
... able to self-assemble into a wide range of highly ... Through biomimicry - technological innovation inspired by nature ... version of self-assembling molecules. A key to accomplishing this ... the form and function of a protein is ...
... October 31, 2012 Scientists at The Scripps ... of an important set of enzymes. The new inhibitors, ... used to study the functions of enzymes known as ... regulate. Early tests in mouse macrophages suggest that DAGL-inhibiting ...
Cached Biology News:Pond skating insects reveal water-walking secrets 2Folding funnels key to biomimicry 2Folding funnels key to biomimicry 3New inhibitors of elusive enzymes promise to be valuable scientific tools 2New inhibitors of elusive enzymes promise to be valuable scientific tools 3
(Date:9/19/2014)... , Sept. 19, 2014  Nektar Therapeutics ... from preclinical studies characterizing the analgesic profiles of ... kappa opioid receptor agonist molecules. The preclinical research ... medicinal chemistry platform. The analgesic properties ... the medical literature. 1,2 Kappa opioid receptors ...
(Date:9/19/2014)... NC (PRWEB) September 19, 2014 ... Biobased Product Label for its Organic Cotton . ... product’s amount of renewable biobased ingredients meets or exceeds ... intermediate materials composed in whole or in significant part ... logo/label will allow our Organic cotton to be immediately ...
(Date:9/19/2014)... 2014 , The first grants ... Paediatric Endocrinology (ESPE) Meeting  Investment supports innovative ... in the field of growth  , EMD ... Germany , today announced the first recipients of ... awards were announced during a Satellite Symposium organized by ...
(Date:9/18/2014)... 18, 2014 HealthTronics, Inc ... interventional radiology products and services, announced that a ... and cryoablation) versus external beam radiotherapy (EBRT) is ... American Urological Association (MAAUA) Annual Meeting in Baltimore, ... Effectiveness of Cryosurgery and External Beam Radiation as ...
Breaking Biology Technology:Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 2Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 3Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 4Nektar Presents Positive Preclinical Data on Oral, Peripherally-Acting Kappa Agonist Molecules at 2014 American Academy of Pain Management Meeting 5Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3HealthTronics Announces Data Comparing Cryotherapy Versus Radiation for Treating Prostate Cancer Poster Presented at the American Urological Association Regional Meeting 2
... 16 Scientists at Biomodels have successfully ... treatment-relat e d fatigue (CTRF). The ... independent of anemia or weight loss and persists long after cancer ... will be presented today at the American Association for Cancer Research-NCI-EORTC ...
... Nov. 16 Neogen Corporation (Nasdaq: NEOG ) today announced ... With the split, shareholders of record on Nov. 30, 2009, will ... , The stock split will be effected in the form ... common stock on Dec. 15, 2009. As of today, Neogen has ...
... 16 Cornerstone Therapeutics Inc. (Nasdaq CM: CRTX), a ... significant products primarily for the respiratory and related markets, ... Chief Financial Officer, will be presenting a corporate overview ... at 9:00AM EST on Wednesday, November 18, 2009 ...
Cached Biology Technology:Biomodels Scientists Report Development of a Novel Model for Cancer Treatment-Related Fatigue 2Neogen Announces 3 for-2 Stock Split 2Cornerstone Therapeutics to Present at the 6th Annual Lazard Capital Markets Healthcare Conference 2
BD BioCoat Laminin 100 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse laminin....
...
... is used as an internal standard for ... dilution mass spectrometry. 5-OxoETE is a polyunsaturated ... 5-HETE in human neutrophils. It stimulates cytosolic ... of 2 nM. 5-OxoETE selectively stimulates the ...
Mouse monoclonal antibody raised against a full length recombinant ATF3. NCBI Entrez Gene ID = ATF3...
Biology Products: