Navigation Links
Neurons hard wired to tell left from right
Date:3/30/2008

It's well known that the left and right sides of the brain differ in many animal species and this is thought to influence cognitive performance and social behaviour. For instance, in humans, the left half of the brain is concerned with language processing whereas the right side is better at comprehending musical melody.

Now researchers from UCL publishing their work in the open access journal Neural Development have pinpointed for the first time the left/right differences in how brains are wired at the level of individual cells. To do this, a research team led by Stephen Wilson looked at left and right-sided neurons (nerve cells) in a part of the brain called the habenula.

By causing habenular neurons to produce a bright green fluorescent protein they saw that they form remarkable "spiral-shaped" axons, the long nerve fibres that act as the nervous system's transmission lines.

"It's clear that the left and right halves of the brain process different types of information but almost nothing is known about the differences in the brain's circuitry which achieve this" says Wilson. "One possibility is that totally different types of neuron might be found on the left and right. Alternatively, both sides could contain the same building blocks but put them together in different ways".

The researchers saw that there are two types of habenular neuron and both types can be found on both left and right sides. However, whilst most left-sided cells have spiral axons shaped into a domed crown, such neurons are not very common on the right. Instead, most right-sided cells form flat, shallow spirals, and these are formed only occasionally on the left.

"In the same way that an engineer can make different electronic circuits from the same set of electronic components, so the left and right halves of the brain use the same types of neuron but in different combinations" explains Isaac Bianco, the student who did this work as part of his PhD studies.

The left and right habenular circuits both connect to the same part of the brain and the researchers found that this target can either combine signals from the left and right or handle them independently.

"Even though language is processed largely on the left side of the human brain, people don't speak with only one half of their mouth. The brain must contain circuits which take information from the left or right and then send it on to targets on both sides of the body" says Wilson.


'/>"/>

Contact: Charlotte Webber
charlotte.webber@biomedcentral.com
44-020-763-19980
BioMed Central
Source:Eurekalert

Related biology news :

1. Weill Cornell team discovers how brains own tPA helps regulate blood flow to neurons
2. Overexcited neurons not good for cell health
3. The birth and death of dopamine neurons: A new model for neurodegeneration
4. The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases
5. Mice use specialized neurons to detect carbon dioxide in the air
6. Humans appear hardwired to learn by over-imitation
7. Northern right whales head south to give birth, leave genetic fingerprints with NOAA researchers
8. Bright lights: Mystery of glowing antibody solved by Scripps research scientists
9. UMMS and CIW grant key RNAi rights to Oxford Biomedica
10. UFs new owl butterfly species naming rights auctioned for $40,800
11. Everglades phosphorus limits on the right track, but more is needed
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... June 27, 2016 Research and Markets has ... 2016-2020" report to their offering. ... America to grow at a CAGR of 12.28% during ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
(Date:6/22/2016)... BETHESDA, Md. , June 22, 2016  The American ... by Trade Show Executive Magazine as one of ... Summit on May 25-27 at the Bellagio in ... based on the highest percentage of growth in each of ... number of exhibiting companies and number of attendees. The 2015 ...
(Date:6/22/2016)... LOS ANGELES , June 22, 2016 ... of identity management and verification solutions, has ... cutting edge software solutions for Visitor Management, ... ® provides products that add functional ... The partnership provides corporations and venues with ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 2016 Houston Methodist Willowbrook Hospital has ... Association to serve as their official health care ... Willowbrook will provide sponsorship support, athletic training services, ... coaches, volunteers, athletes and families. "We ... Association and to bring Houston Methodist quality services ...
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
(Date:6/23/2016)... , ... June 23, 2016 , ... STACS DNA Inc., ... Leader at the Arkansas State Crime Laboratory, has joined STACS DNA as a Field ... DNA team,” said Jocelyn Tremblay, President and COO of STACS DNA. “In further expanding ...
(Date:6/23/2016)... 2016  Blueprint Bio, a company dedicated to identifying, ... community, has closed its Series A funding round, according ... "We have received a commitment from Forentis Fund ... to meet our current goals," stated Matthew Nunez ... to complete validation on the current projects in our ...
Breaking Biology Technology: