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Neurons get their neighbors to take out their trash
Date:6/19/2014

t the common understanding that each cell takes care of its own trash," says Marsh-Armstrong. It is particularly interesting that the newly discovered process occurs at the optic nerve head, he notes, as that is the site thought to be at fault in glaucoma. He plans to investigate whether the mitochondria disposal process is relevant to this disease, the second leading cause of blindness worldwide.

But the implications of the results go beyond the optic nerve head, Marsh-Armstrong says, as a buildup of "garbage" inside cells causes neurodegenerative diseases such as Parkinson's, Alzheirmer's and ALS. "By showing that this type of alternative disposal happens, we've opened up the door for others to investigate whether similar processes might be happening with other cell types and cellular parts other than mitochondria," he says.


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Contact: Shawna Williams
shawna@jhmi.edu
410-955-8236
Johns Hopkins Medicine
Source:Eurekalert

Page: 1 2

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