Navigation Links
Neurons can use local stores for communication needs
Date:5/26/2014

Researchers reveal that neurons can utilize a supremely localized internal store of calcium to initiate the secretion of neuropeptides, one class of signaling molecules through which neurons communicate with each other and with other cells. The study appears in The Journal of General Physiology.

Neuropeptides are released from neurons through a process thatlike other secretory eventsis triggered primarily by the influx of calcium into the neuron through voltage-gated channels. Although neuropeptides are stored in large dense core vesicles (LDCVs) that also contain large amounts of calcium, it has been unclear whether these locally based calcium supplies can also be used to modulate secretion.

A team of researchers led by Jos Lemos from the University of Massachusetts Medical School examined the mechanisms at play during secretion of vasopressin from nerve terminals in the posterior pituitary gland, which releases the neuropeptide into the blood so that it can make its way to the kidney and regulate water retention. The researchers found that certain intracellular calcium channels known as ryanodine receptors are likely responsible for mobilizing calcium from LDCVs to facilitate vasopressin release. The findings indicate that neurons have a greater capacity than previously appreciated to fine-tune the release of neuropeptides and thereby their communications with other cells.


'/>"/>
Contact: Rita Sullivan King
news@rupress.org
212-327-8603
Rockefeller University Press
Source:Eurekalert  

Page: 1

Related biology news :

1. Geniposide protects hippocampal neurons via the non-classical estrogen signaling pathway
2. Studies identify spinal cord neurons that control skilled limb movement
3. 7.0T NMR assesses changes in hippocampal neurons in animal models of Alzheimers disease
4. Short-term environmental enrichment exposure induces maturity of newborn neurons
5. Special function of nestin+ neurons in medial septum-diagonal band of Broca in adult rats
6. Light-activated neurons from stem cells restore function to paralyzed muscles
7. Who reprograms rat astrocytes into neurons?
8. Researchers generate new neurons in brains, spinal cords of living adult mammals
9. Research of zebrafish neurons may lead to understanding of birth defects like spina bifida
10. Cc to the brain: How neurons control fine motor behavior of the arm
11. Mannotriose promotes survival of hippocampal neurons
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Neurons can use local stores for communication needs
(Date:5/6/2017)... 2017 RAM Group , Singaporean ... breakthrough in biometric authentication based on a ... to perform biometric authentication. These new sensors are based ... by Ram Group and its partners. This sensor will ... chains and security. Ram Group is a next ...
(Date:4/13/2017)... , April 13, 2017 UBM,s Advanced Design ... will feature emerging and evolving technology through its ... Summits will run alongside the expo portion of the ... panels and demonstrations focused on trending topics within 3D ... design and manufacturing event will take place June 13-15, 2017 ...
(Date:4/11/2017)... 11, 2017 NXT-ID, Inc. (NASDAQ:   ... announces the appointment of independent Directors Mr. Robin D. ... Board of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , ... forward to their guidance and benefiting from their considerable expertise ...
Breaking Biology News(10 mins):
(Date:9/20/2017)... Westport, CT (PRWEB) , ... September 20, 2017 , ... ... 2nd annual multi-city Fueling the Growth pitch competition to uncover the top technology-driven, ... Growth will be an integral part of each city’s entrepreneurial events going on that ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... molecular manufacturing and other transformative technologies, announced the winners for the 2017 Foresight ... other for Theory in nanotechnology/molecular manufacturing. , Established in 1993 and named in ...
(Date:9/19/2017)... ... September 19, 2017 , ... VetStem Biopharma ’s CEO and founder, Dr. Bob Harman ... Riordan’s new book "Stem Cell Therapy: A Rising Tide". Dr. Harman and Dr. Riordan ... bonded over an interest in the potential of stem cell therapy and a fast friendship ...
(Date:9/19/2017)... ... September 19, 2017 , ... ... announced a partnership with Cytena GmbH to launch the CloneSelect™ Single-Cell Printer™ in ... analysis to isolate single cells and provide visual documentation of monoclonality for use ...
Breaking Biology Technology: