Navigation Links
Neuronal diversity makes a difference, says Carnegie Mellon study
Date:8/29/2010

PITTSBURGHMuch like snowflakes, no two neurons are exactly alike. But it's not the size or shape that sets one neuron apart from another, it's the way it responds to incoming stimuli. Carnegie Mellon University researchers have discovered that this diversity is critical to overall brain function and essential in how neurons process complex stimuli and code information. The researchers published their findings, the first to examine the function of neuron diversity, online in Nature Neuroscience.

"I think neuroscientists have, at an intuitive level, recognized the variability between neurons, but we swept it under the rug because we didn't consider that diversity could be a feature. Rather, we looked at it as a fundamental reflection of the imprecision of biology," said Nathan N. Urban, professor and head of CMU's Department of Biological Sciences. "We wanted to reconsider that notion. Perhaps this diversity is important maybe it serves some function."

Estimates say that the human brain alone has upwards of 100 billion neurons, which can be broken down into a number of different types. While members of the same type look structurally alike, and, as a group, contribute to completing the same overall task, each individual neuron in that group fires in response to subtle differences in the incoming stimulus. Typically neuroscientists average out this heterogeneity to obtain their results, assuming that the variability is a "bug of biology."

"When we think about computer chips, variability in hardware clearly can be very destructive. Manufacturers spend a lot of time and expense making sure each processor on a chip is identical," Urban said. "The brain is considered to be one of the most sophisticated computers there is. We were intrigued by the idea that the brain might make use of the messy, complex nature of its biological hardware to function more efficiently."

Urban and postdoctoral student Krishnan Padmanabha
'/>"/>

Contact: Jocelyn Duffy
jhduffy@andrew.cmu.edu
412-268-9982
Carnegie Mellon University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. York U autism-related study discovers how drug interferes with neuronal cell function
2. Tissue engineering, imaging neuronal circuits featured in Cold Spring Harbor Protocols
3. The protein Srebp2 drives cholesterol formation in prion-infected neuronal cells
4. Caltech scientists reveal how neuronal activity is timed in brains memory-making circuits
5. Iron is involved in prion disease-associated neuronal demise
6. Chemist receives NIH funding to unravel tricks of neuronal wiring
7. Claudin 11 stops the leaks in neuronal myelin sheaths
8. How neuronal activity leads to Alzheimers protein cleavage
9. Analysis of Ashkenazi Jewish genomes reveals diversity, history
10. Top predators and biodiversity historically pressured in Stellwagen Bank National Marine Sanctuary
11. Scientists uncover global distribution of marine biodiversity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Neuronal diversity makes a difference, says Carnegie Mellon study
(Date:2/12/2015)... , Feb. 12, 2015 NXT-ID, Inc. (NASDAQ: ... "Company"), a biometric authentication company focused on the growing ... provisional patent 62/113114 for DISTRIBUTED METHOD AND ... The patent further establishes NXT-ID,s position in the ... property portfolio the ability for multiple devices to collaborate ...
(Date:2/5/2015)... PARK, North Carolina , 5. Februar ... 35. Jahr als spezialisiertes Logistikunternehmen und hat ... als einzige klinische Logistikfirma (Clinical Logistics Organization ... Kernbotschaft der neuen Kampagne lautet First ... Lieferungen. Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
(Date:2/5/2015)... 27, 2015   Marvin Test Solutions ... innovative test solutions for military, aerospace, and ... its TS-323 GENASYS Test Platform ... GENASYS is a high-performance PXI-based system designed ... that require performance functional testing. GENASYS features ...
Breaking Biology News(10 mins):NXT-ID Patents Collaborative Services to Enable the "Internet of Things" 2NXT-ID Patents Collaborative Services to Enable the "Internet of Things" 3Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 2Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 4
... In recent years, the possible applications for double-walled ... those working on developing renewable energy technologies. These ... thin enough to be transparent, yet can still ... advanced solar panels, sensors and a host of ...
... for Glycomics in collaboration with colleagues at the ... to identifying a broad spectrum treatment for the ... These highly-infectious viruses are the leading cause of ... of hospitalisations in the developed world, and hundreds ...
... Dec. 23, 2008 -- The reproductive spores of many ... to new research by mycologists and applied mathematicians at ... this week in the Proceedings of the National ... fungal spores is within one percent of the absolute ...
Cached Biology News:Researchers find chink in the armor of viral 'tummy bug' 2In many fungi, reproductive spores are remarkably aerodynamic 2
(Date:2/27/2015)... The fully automated supercritical fluidic chromatography-based ... analyze up to 48 samples utilizing automatic extraction ... targets by mass spectrometry. , The Nexera ... requirements of a wide range of applications, including ... search for disease biomarkers, additives in forming polymers, ...
(Date:2/27/2015)... South San Francisco, CA (PRWEB) February 27, 2015 ... it is joining forces on February 28 with patients ... globally to raise awareness for Rare Disease Day®. ... of rare diseases and calling attention to the special ... support community around them. , “Cytokinetics is proud to ...
(Date:2/26/2015)... -- On behalf of biotech client GenScript USA, ... & Spitzer, P.A. (Wilentz) secured a significant jury verdict ... excess of $10 million. The jury determined that Genewiz ... it improperly hired one or more of GenScript,s employees.  ... notwithstanding the verdict, a new trial, and remittitur. ...
(Date:2/26/2015)... Calif. , Feb. 26, 2015   Regulus ... biopharmaceutical company leading the discovery and development of innovative ... Xanthopoulos , Ph.D., President and Chief Executive Officer of ... and Company 35 th Annual Healthcare Conference on ... conference is being held at the Boston Marriott Copley ...
Breaking Biology Technology:Shimadzu Corporation Launches Nexera UC - The World’s Foremost Unified Chromatography System 2Shimadzu Corporation Launches Nexera UC - The World’s Foremost Unified Chromatography System 3Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 2Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 3Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 4Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 5Cytokinetics Joins Global Movement to Raise Awareness for Rare Diseases 6Wilentz Client GenScript Awarded $10 Million in Trade Secrets Case Against Genewiz 2Wilentz Client GenScript Awarded $10 Million in Trade Secrets Case Against Genewiz 3Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 2Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 3
... Inc. (Nasdaq: HGSI ) announced today that ... Healthcare Conference will be webcast,and may be accessed ... ), A member of Human Genome ... on Thursday, September 4, 2008 at 8:35 am ...
... /PRNewswire-FirstCall/ - Oncolytics Biotech Inc.,("Oncolytics") (TSX:ONC, NASDAQ:ONCY) ... Administration (FDA) review, the Company is initiating ... administration of REOLYSIN(R) in,combination with paclitaxel and ... (NSCLC) with K-RAS or EGFR-activated tumours. The ...
... 2 /PRNewswire-FirstCall/ - OncoGenex,Pharmaceuticals, Inc. (NASDAQ: ... today that it has granted to Eagle ... and commercialize TOCOSOL(R),Paclitaxel. Under the terms of ... payments from future TOCOSOL Paclitaxel sales and ...
Cached Biology Technology:/R E P E A T -- Oncolytics Biotech Inc. Announces U.S. Phase 2 Combination Clinical Trial for Non-Small Cell Lung Cancer Patients with K-RAS or EGFR-Activated Tumours/ 2/R E P E A T -- Oncolytics Biotech Inc. Announces U.S. Phase 2 Combination Clinical Trial for Non-Small Cell Lung Cancer Patients with K-RAS or EGFR-Activated Tumours/ 3/R E P E A T -- Oncolytics Biotech Inc. Announces U.S. Phase 2 Combination Clinical Trial for Non-Small Cell Lung Cancer Patients with K-RAS or EGFR-Activated Tumours/ 4OncoGenex Pharmaceuticals announces out-license of TOCOSOL Paclitaxel to Eagle Pharmaceuticals 2OncoGenex Pharmaceuticals announces out-license of TOCOSOL Paclitaxel to Eagle Pharmaceuticals 3
... used technique for studying protein function and ... SDS-PAGE and transferred to a membrane such ... probed with specific antibodies. Unlike nucleic acid ... and Northern blots, it has been difficult ...
... Basic Package Superior Protein Detection and ... ProXPRESS 2D Proteomic Imaging System is a ... proteomic and general life science research applications. ... use of all dyes in the UV ...
... Introducing our Regulatory Edition of Molecular Imaging ... systems for life science research and drug ... compliance with U.S. Food and Drug Administrations ... 11 Electronic Records; Electronic Signatures [21 CFR ...
... is a 16 amino acid (amino acids 3-18) synthetic peptide ... The sequence of this peptide is (amino to carboxy terminus): ... V - K - L - R - A - ... K(18). This peptide may be used for neutralization ...
Biology Products: