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Neurimmune Therapeutics Announces Advancement of Alzheimers Program into Preclinical Development
Date:8/18/2009

Zurich, Switzerland, August 18, 2009 / b3c newswire / -Neurimmune Therapeutics AG today announced that, following the successful completion of key research milestones, its lead human therapeutic antibody for Alzheimers disease has advanced into preclinical development, triggering milestone payments of an undisclosed amount from Biogen Idec (NASDAQ: BIIB). Neurimmune partnered with Biogen Idec for the worldwide development and commercialization of novel, fully human antibodies for the treatment of Alzheimers disease in November 2007. The alliance focuses on the development of antibodies that bind to amyloid beta (Abeta), a pathogenic molecule thought to cause neurodegeneration and loss of cognitive function in Alzheimers patients.

Neurimmunes unique Reverse Translational Medicine (RTM) technology platform combined with in-depth expertise in neuroscience played a critical role in moving the program forward. The fact that we could reach all preclinical milestones in such a short period of time shows that our RTM technology can significantly accelerate the transition from discovery to development of human monoclonal antibodies, said Jan Grimm, Chief Scientific Officer of Neurimmune Therapeutics.

The rapid advancement into preclinical development demonstrates the progress and productivity of our collaboration with Biogen Idec we are very happy to work with a partner that has such extensive and valuable experience in the development of biopharmaceuticals. The significant milestone payments also provide Neurimmune with additional financial stability to support the sustainable future development of our company, said Michael Salzmann, COO and General Manager of Neurimmune Therapeutics.

Biogen Idec is globally recognized as a leader in the development of innovative therapies for neurologic diseases, and this program is an important entry into Alzheimers disease for us, said Kenneth Rhodes, PhD, Vice President, Discovery
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