Navigation Links
Neiker-Tecnalia identifies antitumour proteins in the latex of the plant Euphorbia trigona
Date:6/21/2012

The purified proteins by the Department of Biotechnology of Neiker-Tecnalia have demonstrated their ability to inhibit the growth of several tumor cell lines. This property shows that the latex proteins of this plant, which is very prolific and easily acclimated, could be considered in clinical trials for cancer treatment due to its anti-tumor activity. The research has been done in collaboration with the University of Oviedo (Spain) and with funding from the Department for the Environment, Territorial Planning, Agriculture and Fisheries of the Government of the Basque Autonomous Community (region).

Latex comprises various substances including proteins that play a very active role in defending the plant, like proteases, chitinases, oxidases and lectins. These latter proteins constitute a very valuable tool for studying membrane structure and for detecting malignant transformations, among other types of research. Identifying plants which have proteins of interest in biomedicine is one of scientific objectives. In this aspect, Neiker-Tecnalia has selected Euphorbia trigona, a succulent plant of African origin and belonging to the euphorbiaceae family.

In the latex of Euphorbia trigona the scientists of the R+D Centre and the University of Oviedo found three proteins belonging to the RIP (Ribosome Inactivating Protein) family. The purified proteins by specialists were able to inhibit eukaryotic ribosomes in cell-free systems, and also showed cytotoxic activity -the ability to inhibit cell growth- when tested with different tumor cell lines.

In addition to the antitumour activity, the researchers observed a possible antifungal activity the ability to fight infections caused by fungi of the lectins present in the latex of this plant. This potential antifungal activity opens an interesting line of research in finding new uses for latex proteins of E. trigona against various diseases.

Lectins currently represent
'/>"/>

Contact: Irati Kortabitarte
i.kortabitarte@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Page: 1 2

Related biology news :

1. Research identifies specific bacteria linked to indoor water-damage and mold
2. UI professor identifies largest known crocodile
3. Collaborative research team identifies safe upper level for vitamin A consumption for puppies
4. 23andMe identifies 5 significant genetic associations for hypothyroidism
5. Plant DNA speaks English, identifies new species
6. Identification of differential proteins in maternal serum with Down syndrome
7. Speeding up drug discovery with rapid 3-D mapping of proteins
8. A non-invasive intracellular thermometer with fluorescent proteins has been created
9. Discovered a new checkpoint of cell cycle control through joint action of 2 proteins
10. UCLA researchers develop way to strengthen proteins with polymers
11. Discovery of plant proteins may boost agricultural yields and biofuel production
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2015)... 2015 Research and Markets  ( http://www.researchandmarkets.com/research/xsgs2s/gesture ... "Gesture Recognition & Touchless Sensing Market by Technology ... Others), Product (Biometric & Sanitary Equipment) & by ... to their offering. The total gesture ... reach $ 23.55 Billion by 2020 at a ...
(Date:6/8/2015)... WASHINGTON , June 8, 2015  The ... announced today their selection of Troy Potter ... Chairman, effective immediately. SIBA is a non-profit association ... promote responsible policy, education and implementation of solutions ... public platforms. ...
(Date:6/4/2015)... , June 4, 2015  Today, the co-chairs of the ... involving U.S. high-level biocontainment labs and USA ... co-chairs expressed grave concerns over the findings of lax safety ... nation,s lab biosecurity. ... is extremely troubling," said Joe Lieberman , former senator ...
Breaking Biology News(10 mins):Global Gesture Recognition & Touchless Sensing (Technology, Application & Products) Market 2015-2020 2Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 2Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 3Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 4Secure Identity & Biometrics Association (SIBA) Names Troy Potter of L-3 National Security Solutions as Chairman 5Biodefense Panel Expresses Grave Concerns over Findings at Nation's Research Labs 2Biodefense Panel Expresses Grave Concerns over Findings at Nation's Research Labs 3
... September 12, 2011A study presented today by Universit Laval researchers ... in Quebec City revealed that the risk of insomnia is ... one member is an insomniac. The research team, ... of Psychology, came to these conclusions following a study involving ...
... liquids has been intimately entwined since Lon Foucault discovered the ... travels more slowly in water than in air. This physical ... collect and drive light to where it can be the ... on optofluidics, the study of microfluidicsthe microscopic delivery of fluids ...
... induced pluripotent stem cells were first derived in 2007, scientists ... cells, which are sourced in early-stage embryos. Both cell ... the body, but their origins in embryonic and adult ... both cell types have great potential in basic biological research ...
Cached Biology News:A guiding light for new directions in energy production 2A guiding light for new directions in energy production 3Study reveals critical similarity between two types of do-it-all stem cells 2Study reveals critical similarity between two types of do-it-all stem cells 3
(Date:6/29/2015)... ... June 30, 2015 , ... This cutting edge standard making is ... Featuring 12 distinct peaks, the WAV-8 is the world’s first cuvette-shaped, solid-state filter that ... into the NIR range. Previous spectrophotometer calibration standards, such as those made from didymium ...
(Date:6/29/2015)... , ... June 29, 2015 , ... ... CAGR of around 19% during the forecast period (2015 to 2020). The market ... upsurge in government and corporate funding for R&D. However, lack of adequate healthcare ...
(Date:6/29/2015)... -- MiMedx Group, Inc. (NASDAQ: MDXG ), the leading ... processes to develop and market advanced products and therapies ... Ophthalmic and Dental sectors of healthcare, announced that its ... awarded the Lifetime Achievement Award in the EY Entrepreneur ... The Entrepreneur Of The Year Program, now in its ...
(Date:6/29/2015)... ... ... The StampedeCon 2015 Big Data Conference will be taking place ... will bring top technology professionals to St. Louis. Top industry speakers will share their ... The event is proudly sponsored by DataStax, Cisco, World Wide Technology, Hortonworks, OCI, HP, ...
Breaking Biology Technology:FireflySci Releases Spectrophotometer Calibration Standards for NIR Wavelength Accuracy Verification 2FireflySci Releases Spectrophotometer Calibration Standards for NIR Wavelength Accuracy Verification 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 2Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 3Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 4Microfluidics Market Growing at 19.3% CAGR To 2020 – New research available at ReportsnReports.com 5EY Entrepreneur Of The Year Program Recognizes Pete Petit, The Chairman & CEO of MiMedx 2StampedeCon Announces 2015 Agenda 2StampedeCon Announces 2015 Agenda 3
... Transition to ... Market, SUNNYVALE, Calif., Feb. 28 Cepheid (Nasdaq:,CPHD) today announced financial results for the ... year 2007:, -- Total revenues of $129.5 million, a 48 percent increase from ... - Total product sales of $116.5 million, a 41 percent increase ...
... the Kansas,Bioscience Authority, Kansas State University is gearing ... will keep research laboratories,safe and secure -- so ... research to combat infectious diseases., Bioscience research ... to unprecedented demand for biosafety and biocontainment,training, according ...
... Feb. 28 A free white paper ... environmental health and,safety (EH&S) compliance programs is ... "Small and midsized companies and institutions ... safety compliance programs,involving federal, state, and local ...
Cached Biology Technology:Cepheid Reports Fourth Quarter and Full Year 2007 Results 2Cepheid Reports Fourth Quarter and Full Year 2007 Results 3Cepheid Reports Fourth Quarter and Full Year 2007 Results 4Cepheid Reports Fourth Quarter and Full Year 2007 Results 5Cepheid Reports Fourth Quarter and Full Year 2007 Results 6Cepheid Reports Fourth Quarter and Full Year 2007 Results 7Cepheid Reports Fourth Quarter and Full Year 2007 Results 8Cepheid Reports Fourth Quarter and Full Year 2007 Results 9Cepheid Reports Fourth Quarter and Full Year 2007 Results 10Cepheid Reports Fourth Quarter and Full Year 2007 Results 11Cepheid Reports Fourth Quarter and Full Year 2007 Results 12Cepheid Reports Fourth Quarter and Full Year 2007 Results 13Cepheid Reports Fourth Quarter and Full Year 2007 Results 14K-State Preparing to Share Expertise With Bioscientists 2White Paper Details Environmental Health & Safety Compliance Strategies for Laboratories 2
HybriWell™ hybridization sealing system, 20 mm diameter chamber, 0.15 mm deep *set of 100*...
Recombinant Equine TNF-alpha/TNFSF1A, CF...
GRADIENT MAKER, 30 ML, 1 EA. Category: Protein Vertical Instruments....
DALT GRADIENT MAKER,230V, 1 EA. Category: 2D DALT Systems....
Biology Products: