Navigation Links
Neiker-Tecnalia identifies antitumour proteins in the latex of the plant Euphorbia trigona
Date:6/21/2012

The purified proteins by the Department of Biotechnology of Neiker-Tecnalia have demonstrated their ability to inhibit the growth of several tumor cell lines. This property shows that the latex proteins of this plant, which is very prolific and easily acclimated, could be considered in clinical trials for cancer treatment due to its anti-tumor activity. The research has been done in collaboration with the University of Oviedo (Spain) and with funding from the Department for the Environment, Territorial Planning, Agriculture and Fisheries of the Government of the Basque Autonomous Community (region).

Latex comprises various substances including proteins that play a very active role in defending the plant, like proteases, chitinases, oxidases and lectins. These latter proteins constitute a very valuable tool for studying membrane structure and for detecting malignant transformations, among other types of research. Identifying plants which have proteins of interest in biomedicine is one of scientific objectives. In this aspect, Neiker-Tecnalia has selected Euphorbia trigona, a succulent plant of African origin and belonging to the euphorbiaceae family.

In the latex of Euphorbia trigona the scientists of the R+D Centre and the University of Oviedo found three proteins belonging to the RIP (Ribosome Inactivating Protein) family. The purified proteins by specialists were able to inhibit eukaryotic ribosomes in cell-free systems, and also showed cytotoxic activity -the ability to inhibit cell growth- when tested with different tumor cell lines.

In addition to the antitumour activity, the researchers observed a possible antifungal activity the ability to fight infections caused by fungi of the lectins present in the latex of this plant. This potential antifungal activity opens an interesting line of research in finding new uses for latex proteins of E. trigona against various diseases.

Lectins currently represent
'/>"/>

Contact: Irati Kortabitarte
i.kortabitarte@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Page: 1 2

Related biology news :

1. Research identifies specific bacteria linked to indoor water-damage and mold
2. UI professor identifies largest known crocodile
3. Collaborative research team identifies safe upper level for vitamin A consumption for puppies
4. 23andMe identifies 5 significant genetic associations for hypothyroidism
5. Plant DNA speaks English, identifies new species
6. Identification of differential proteins in maternal serum with Down syndrome
7. Speeding up drug discovery with rapid 3-D mapping of proteins
8. A non-invasive intracellular thermometer with fluorescent proteins has been created
9. Discovered a new checkpoint of cell cycle control through joint action of 2 proteins
10. UCLA researchers develop way to strengthen proteins with polymers
11. Discovery of plant proteins may boost agricultural yields and biofuel production
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... nucleus, chromosomal DNA is tightly bound to structural ... chromatin. Until about two decades ago, histones were ... material around which the glamorous DNA strands were ... appreciation for how DNA/histone interactions govern gene expression. ... studying the sequence of the genome from cancer ...
(Date:8/28/2014)... of America (ESA) is pleased to announce the selection ... the Society. Honorary Membership acknowledges those who have served ... in the affairs of the Society that has reached ... by the ESA Governing Board and then voted on ... at the Awards Ceremony at Entomology 2014, ESA,s Annual ...
(Date:8/28/2014)... are healthier for your neighbors than traditional cigarettes, ... to a new study from USC. , Scientists ... 10-fold decrease in exposure to harmful particles, with ... exposure to some harmful metals in second-hand e-cigarette ... While tobacco smoke contains high levels of polycyclic ...
Breaking Biology News(10 mins):'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 2'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 3Fred Baxendale selected as Honorary Member of the Entomological Society of America 2Second-hand e-cig smoke compared to regular cigarette smoke 2
... cure for viral infections, may be a strong ... immunocompromised patients, according to an article in the ... (mycoses) were once seen as exotic diseases, but ... healthy patients, fungal infections are a major problem ...
... JOLLA, CALIFORNIA, OCT. 30, 2007 -- In hopes of combating ... bacteria, a team of scientists from the Scripps Research Institute ... day be used in humans to block the onset of ... would work not only on current bacterial resistant stains but ...
... HOUSTON, Oct. 30, 2007 -- Rice University bioengineers ... potential of "hairy roots" as natural factories to ... The study is available online and slated ... American Chemical Society,s bi-monthly journal Biotechnology Progress. ...
Cached Biology News:Gamma interferon could aid fight against fungal infections 2Scripps research team blocks bacterial communication system to prevent deadly staph infections 2Scripps research team blocks bacterial communication system to prevent deadly staph infections 3Could 'hairy roots' become biofactories? 2
(Date:8/29/2014)... August 29, 2014 The global ... billion in 2019. It is expected to grow ... 2019, and was valued at $1.8 billion in ... Transparency Market Research. , For more information regarding ... . , The research report, titled “Companion Diagnostics ...
(Date:8/29/2014)... August 29, 2014 Three Lawrence ... 2014 Hydrogen Production R&D Award for ... splitting water using sunlight. , Shared with collaborators ... the University of Nevada, Las Vegas (UNLV), the ... models of photoelectrochemical solar-hydrogen production and corrosion processes. ...
(Date:8/28/2014)... CA (PRWEB) August 28, 2014 Best ... products for the food processing industry, is asking industry ... side-by side comparison of the E2 soap they’re currently ... Sanitizing Foam Soap . Hand hygiene is critical ... the food processing environment. Six key criteria are identified ...
(Date:8/28/2014)... , Aug. 28, 2014 ... a new market research report ... Whole Exome Sequencing ... (Library Preparation, Target Enrichment), by ... by Synthesis), by Application (Cancer, ...
Breaking Biology Technology:Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 3Livermore Team Awarded for Hydrogen Production Research 2Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 2Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 3Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 4Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 5Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 6Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 7Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 8Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 9Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 10Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 11Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 12Whole Exome Sequencing Market by Product (Systems, Kits (Library Preparation, Target Enrichment), by Services (Sequencing), by Technology (Sequencing by Synthesis), by Application (Cancer, Monogenic disorders) - Global Forecast to 2018 13
... Austria, October 23 GlaxoSmithKline Biologicals,S.A. (GSK) ... of a,collaboration agreement granting GSK exclusive rights ... treating Alzheimer,s by,targeting beta-amyloid., As part ... rights to develop,and commercialise two Alzheimer,s disease ...
... SOMERSET, N.J., Oct. 23 Alfacell Corporation,(Nasdaq: ... on Form 10-K for the,fiscal year ended July ... on Oct. 14, 2008, included an audit opinion ... doubt about the company,s,ability to continue as a ...
... Arena Pharmaceuticals,Inc. (Nasdaq: ARNA ) today announced ... NASDAQ Global Market closes on Thursday,October 30, 2008. That ... and Robert E. Hoffman, Arena,s Vice President,Finance and Chief ... Eastern Time (2:00 p.m. Pacific Time) to discuss the ...
Cached Biology Technology:GlaxoSmithKline and AFFiRiS Sign an Exclusive Licence and Option Agreement for Therapeutic Alzheimer's Disease Candidate Vaccines 2GlaxoSmithKline and AFFiRiS Sign an Exclusive Licence and Option Agreement for Therapeutic Alzheimer's Disease Candidate Vaccines 3Alfacell Receives Going Concern Audit Opinion 2Arena Pharmaceuticals to Report Third Quarter 2008 Financial Results and to Host Conference Call and Webcast on Thursday, October 30, 2008 2Arena Pharmaceuticals to Report Third Quarter 2008 Financial Results and to Host Conference Call and Webcast on Thursday, October 30, 2008 3
Makes gels easy to load and track during electrophoresis. 10X concentrate of Bromophenol Blue, Xylene Cyanol, glycerol solution in TE...
Agarose, low melting/gelling temperature, high MW separation (>1000 bp), 25 g. Suitable for enzymatic modifications. Nuclease-free.Gel point: 24-30 C, EEO (-mr): 300 gm/cm2. Category: Nucleotides &...
Request Info...
Request Info...
Biology Products: