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Needle-size device created to track tumors, radiation dose
Date:4/8/2008

in the same capsule and will be hermetically sealed so that it will not have to be removed from the body," Ziaie said.

The same researchers in 2006 reported findings on the first such miniature device. However, the earlier prototype lacked adequate sensitivity, was too large and not suitable for easy implantation, Ziaie said.

New findings detail the development of a miniaturized and more sensitive dosimeter that can be implanted using a hypodermic needle. Researchers tested the prototype with radioactive cobalt.

The researchers have been funded by the National Science Foundation and recently received a two-year grant from the National Institutes of Health to continue the work. Over that time, the research team will work to simplify the fabrication process so that the devices could be manufactured inexpensively.

A key advantage of the technology is that it does not require intricate circuitry, which could make the device easier and less expensive to manufacture than more complex designs. The system consists of simple electronic devices called capacitors and coils.

The device has a diameter of about 2.5 millimeters, or thousandths of a meter, and is about 2 centimeters long, making it small enough to fit inside a large-diameter needle for injection with a syringe. The current size is small enough to be used in tumors, but researchers will work to shrink the device to about half a millimeter in diameter and half its current length, roughly the size of a rice grain, said Ziaie, who is working with Byunghoo Jung, a Purdue assistant professor of electrical and computer engineering.


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Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University
Source:Eurekalert  

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