Navigation Links
Naturally-occurring apple compounds reduce risk of pancreatic cancer
Date:10/3/2007

Eating flavonol-rich foods like apples may help reduce the risk of pancreatic cancer, says a team of international researchers. Quercetin, which is found naturally in apples and onions, has been identified as one of the most beneficial flavonols in preventing and reducing the risk of pancreatic cancer. Although the overall risk was reduced among the study participants, smokers who consumed foods rich in flavonols had a significantly greater risk reduction.

This study, published in the October 15 issue of the American Journal of Epidemiology, is the first of its kind to evaluate the effect of flavonols compounds found specifically in plants on developing pancreatic cancer. According to the research paper, only a few prospective studies have investigated flavonols as risk factors for cancer, none of which has included pancreatic cancer.

Researchers from Germany, the Univ. of Hawaii and Univ. of Southern California tracked food intake and health outcomes of 183,518 participants in the Multiethnic Cohort Study for eight years. The study evaluated the participants food consumption and calculated the intake of the three flavonols quercetin, kaempferol, and myricetin. The analyses determined that flavonol intake does have an impact on the risk for developing pancreatic cancer.

The most significant finding was among smokers. Smokers with the lowest intake of flavonols presented with the most pancreatic cancer. Smoking is an established risk factor for the often fatal pancreatic cancer, notes the research.

Among the other findings were that women had the highest intake of total flavonols and seventy percent of the flavonol intake came from quercetin, linked to apple and onion consumption.

It is believed that these compounds may have anticancer effects due to their ability to reduce oxidative stress and alter other cellular functions related to cancer development.

Unlike many of the dietary components, flavonols are concentrated in specific foods rather than in broader food groups, for example, in apples rather than in all fruit, notes the research study. Previously, the most consistent inverse association was found between flavonols, especially quercetin in apples and lung cancer, as pointed out in this study. No other epidemiological flavonol studies have included evaluation of pancreatic cancer.

While found in many plants, flavonols are found in high concentrations in apples, onions, tea, berries, kale, and broccoli. Quercetin is most plentiful in apples and onions.


'/>"/>

Contact: Stacie Haaga
Shaaga@USApple.org
703-442-8850
U.S. Apple Association
Source:Eurekalert

Related biology news :

1. Red delicious, Northern Spy apples have most antioxidants, chemists find
2. HortResearch science reveals the natural potential of apples
3. UC Davis researchers reveal apples protective ways
4. Found -- the apple gene for red
5. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
6. Researchers discover chemical compounds that affect plant growth
7. Compounds in plastic packaging act as environmental estrogens altering breast genes
8. Bacterial genome sheds light on synthesizing cancer-fighting compounds
9. Scientists discover the bodys marijuana-like compounds are crucial for stress-induced pain relief
10. Evolution of taste receptor may have shaped human sensitivity to toxic compounds
11. Novel compounds show promise as safer, more potent insecticides
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
(Date:3/31/2016)... 2016   LegacyXChange, ... "Company") LegacyXChange is excited to release its ... to be launched online site for trading 100% guaranteed ... will also provide potential shareholders a sense of the ... an industry that is notorious for fraud. The video ...
(Date:3/22/2016)... PROVO and SANDY, Utah ... Ontario (NSO), which operates the highest sample volume laboratory ... and Tute Genomics and UNIConnect, leaders in clinical sequencing ... announced the launch of a project to establish the ... panel. NSO has been contracted by ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... 28, 2016 The report "Cryocooler ... Cryocoolers), Service (Technical Support, Product Repairs & Refurbishment, Preventive ... Forecast to 2022", published by MarketsandMarkets, the global market ... 2022, at a CAGR of 7.29% between 2016 and ... and 94 Figures spread through 159 Pages and in-depth ...
(Date:4/28/2016)... ... April 28, 2016 , ... Morris Midwest ( http://www.morrismidwest.com ... regional manufacturers at its Maple Grove, Minnesota technical center, May 11-12. The ... Trumpf. Almost 20 leading suppliers of tooling, accessories, software and other related ...
(Date:4/27/2016)... April 27, 2016 NanoStruck ... (OTCPink: NSKQB) ( Frankfurt : 8NSK) ... Pressemitteilung vom 13. August 2015 die Genehmigung von ... um zusätzliche 200.000.000 Einheiten auf 400.000.000 Einheiten zu ... bringen. Davon wurden 157.900.000 Einheiten mit dem ersten ...
(Date:4/27/2016)... ... April 27, 2016 , ... ... preclinical PET (Positron Emission Tomography) and MRI (Magnetic Resonance Imaging) in existing third-party ... and testing novel treatments in small animal subjects. Simultaneous PET/MRI imaging offers a ...
Breaking Biology Technology: