Navigation Links
Natural pest control protein effective against hookworm: A billion could benefit
Date:7/23/2013

A benign crystal protein, produced naturally by bacteria and used as an organic pesticide, could be a safe, inexpensive treatment for parasitic worms in humans and provide effective relief to over a billion people around the world. Researchers from the University of California, San Diego, La Jolla, CA, report on this potentially promising solution in a study published ahead of print in the journal Applied and Environmental Microbiology.

Hookworms, and other intestinal parasites known as helminths infect more than 1 billion people in poverty-stricken, tropical nations, sucking the vitality from the body, and leaving hundreds of millions of children physically and mentally stunted. Current drugs are insufficiently effective, and resistance is rising, but little effort has been made to develop better drugs because the relevant populations do not represent a profitable market for drug companies.

"The challenge is that any cure must be very cheap, it must have the ability to be mass produced in tremendous quantities, safe, and able to withstand rough conditions, including lack of refrigeration, extreme heat, and remote locations," says Raffi Aroian, a researcher on the study.

In earlier research, Aroian and his collaborators described a protein, Cry5B, that can kill intestinal nematode parasitessuch as human hookwormsin infected test animals (hamsters). Cry5B belongs to a family of proteins that are generally accepted as safe for humans. These proteins are produced naturally in Bacillus thuringiensis (Bt), a bacterium which is applied to crops as a natural insecticide on some organic farms, and CryB proteins have been engineered into food crops such as corn and rice, to render them pest resistant.

As shown for the first time in this paper, Cry5B can also be expressed in a species of bacterium, Bacillus subtilis, which is closely related to Bacillus thuringiensis, and which is also related to bacteria
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Herpes infections: Natural killer cells activate hematopoiesis
2. Natural keystone molecules punch over their weight in ecosystems
3. 3D simulation shows how form of complex organs evolves by natural selection
4. University of Southern California scientists reveal natural process that blocks viruses
5. North Carolina Natural Heritage Program earns 2013 Award for Science and Technical Achievement
6. Methane emissions from natural gas local distribution focus of new study
7. New emissions standards would fuel shift from coal to natural gas
8. Men may have natural aversion to adultery with friends wives
9. The natural ecosystems in the Colombian Orinoco Basin are in danger
10. Walking in the footsteps of 19th and 20th century naturalists
11. Newly identified natural protein blocks HIV, other deadly viruses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/hhwlfj/huawei_ascend ... "Huawei Ascend Mate 7 Fingerprint Sensor - Reverse ... Huawei,s technological choice for the fingerprint sensor ... and Samsung,s one. The Ascend Mate 7 presents ... a main actor in capacitive sensing human interface ...
(Date:6/23/2015)... Research and Markets( ... "Body-Worn Temperature Sensors Market - Global Industry ... - 2020" report to their offering. ... global body-worn temperature sensors market. The global body-worn ... basis of types, care setting, patient demographic, applications ...
(Date:6/18/2015)... NEW YORK , June 18, 2015 ... in US$ Million by the following Product Segments, which ... Immunoassay Systems, Chemiluminescence Immunoassay Systems, Radio Immunoassay Systems, and ... for the US, Canada , ... Asia-Pacific , Latin America ...
Breaking Biology News(10 mins):Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2Body-Worn Temperature Sensors Market - Global Industry Analysis 2Global Immunoassay Systems Market 2Global Immunoassay Systems Market 3Global Immunoassay Systems Market 4Global Immunoassay Systems Market 5Global Immunoassay Systems Market 6Global Immunoassay Systems Market 7Global Immunoassay Systems Market 8Global Immunoassay Systems Market 9Global Immunoassay Systems Market 10Global Immunoassay Systems Market 11Global Immunoassay Systems Market 12Global Immunoassay Systems Market 13Global Immunoassay Systems Market 14Global Immunoassay Systems Market 15Global Immunoassay Systems Market 16Global Immunoassay Systems Market 17Global Immunoassay Systems Market 18Global Immunoassay Systems Market 19Global Immunoassay Systems Market 20Global Immunoassay Systems Market 21Global Immunoassay Systems Market 22Global Immunoassay Systems Market 23Global Immunoassay Systems Market 24Global Immunoassay Systems Market 25Global Immunoassay Systems Market 26Global Immunoassay Systems Market 27Global Immunoassay Systems Market 28Global Immunoassay Systems Market 29
... bully so your buddy can get some tail may seem ... some lizards, it also gives a fascinating peek into hard-wired ... on earth looking to reproduce, and their strategies have lessons ... the Proceedings of the National Academy of Sciences provides the ...
... been right all along ?a siesta after a hearty lunch ... of Manchester have for the first time uncovered how brain ... after we eat. , The findings ?published in the scientific ... eating disorders as well as understanding levels of consciousness. , ...
... Wisconsin-Madison School of Medicine and Public Health has discovered a ... of blood vessels, or angiogenesis. , The finding may ... the senior author on the study, a professor of pharmacology ... Center. , The research, published in the Journal of ...
Cached Biology News:Nice guys do finish first in lizards' evolutionary race 2Why we could all do with a siesta 2New angiogenesis finding may help fight cancer growth 2New angiogenesis finding may help fight cancer growth 3New angiogenesis finding may help fight cancer growth 4
(Date:6/30/2015)... 30, 2015  The University of California, San ... and UC San Diego Extension announced their third ... Aug.  12 – 14, 2015, at UC San ... provides an intense exposure to best practices and ... well-suited to biologists, process engineers and business executives ...
(Date:6/30/2015)... ... June 30, 2015 , ... ... She has accepted the position of vice president of instruction at Chippewa Valley ... , “I greatly appreciated the opportunity to lead SIUE during the past three ...
(Date:6/29/2015)... Pharnext SAS today announced that data related to its ... Type 1A (CMT1A), is being presented in four posters and ... Biennial Meeting at the Quebec Congress Center in ... 2015. At Poster Viewing Session 4, four posters ... EDT: Poster 23: "A Meta-Analysis Of Randomized ...
(Date:6/29/2015)... WASHINGTON , June 29, 2015  AACC, ... to better health through laboratory medicine, is pleased ... journal, Clinical Chemistry , has increased to ... Reports. This increase places Clinical Chemistry ... and reflects the significant influence of the research ...
Breaking Biology Technology:UC San Diego Extension to Offer Third Annual Microbial Fermentation Workshop 2SIUE’s Furst-Bowe Accepts VP of Instruction at CVTC 2SIUE’s Furst-Bowe Accepts VP of Instruction at CVTC 3Pharnext's PXT-3003 Featured in Multiple Presentations at 2015 Peripheral Nerve Society Biennial Meeting 2AACC's Journal, Clinical Chemistry, Continues to Have Significant Impact on Medical Testing, Healthcare 2AACC's Journal, Clinical Chemistry, Continues to Have Significant Impact on Medical Testing, Healthcare 3
... chips, open-source OS , ,Chippewa Falls, Wis.This is crunch ... than one. , ,As the companys sprawling manufacturing plant here ... final days of its fiscal first quarter, it is hoping ... Altix 3000 family of servers and superclusters, can carry it ...
... We recently had the opportunity to discuss ... more efficient information technology based services - internally and ... to help entrepreneurs with investment funding and health insurance. ... faces as it attempts to limit unsolicited e-mail. ...
... you receive an e-mail from Microsoft and it even looks ... Be Careful! These e-mails appear to be the result ... shares. It is a Mass-Mailing worm which disables processes related ... , ,According to Microsoft, the worm typically spoofs ...
Cached Biology Technology:SGI banking on Altix to pay the freight 2SGI banking on Altix to pay the freight 3WTN Interview with Governor Doyle 2WTN Interview with Governor Doyle 3WTN Interview with Governor Doyle 4WTN Interview with Governor Doyle 5WTN Interview with Governor Doyle 6Fake Microsoft E-Mails Are WORMS in Disguise 2
... number is a new product ... Cornings product number. If showing ... under the old Sigma-Aldrich number ... for assistance. Mfr Desig: ...
... Virgin, optically clear polystyrene with frosted ... coordinates for cell counting. 100% integrity ... a new product number, created to ... showing no availability yet, please order ...
... LIC Duet™ T7•Tag ® Ek Adaptor ... operator, ribosome binding site (rbs), ATG translation ... sequence. The T7•Tag is a small epitope ... detection of the target protein with T7•Tag ...
The LIC Duet™ Mini Adaptor encodes a T7 promoter, lac operator, ribosome binding site (rbs), and an ATG translation initation codon. This adaptor is designed for expression of a target protei...
Biology Products: