Navigation Links
Nationwide Children's Hospital awarded $11.5 million contract extension for biospecimen banking
Date:1/10/2011

Nationwide Children's Hospital was awarded $11.5 million from the National Cancer Institute (NCI) late last year to continue its role as one of two Biospecimen Core Resources (BCR) for The Cancer Genome Atlas (TCGA). Contract awards to Nationwide Children's could total up to $49.2 million over six years.

TCGA is a signature program of the National Institutes of Health (NIH). The goal of the project is to perform cutting-edge genetic testing of tumors from more than 10,000 patients with one of 20 different cancers, thereby improving the ability to diagnose, treat and prevent the disease. Nationwide Children's was awarded an initial $7.7 million contract starting in November 2009 to begin operating in this role.

As a BCR for TCGA, The Research Institute at Nationwide Children's is central to the process of acquiring both tumor and normal tissue samples and their accompanying clinical information from contributing medical and research centers. BCR functions include analyzing all specimens to ensure they meet rigorous quality standards for each tumor type and ensuring that the clinical information for each sample is available. Once the optimal specimens are examined and processed, the BCR distributes the DNA and RNA extracted from the specimens to researchers throughout the national TCGA research network.

"TCGA has already yielded scientific discoveries that are now being used in clinical trials. We are excited to contribute to future research into breast, endometrial, melanoma, and other cancers," said Dr. Julie Gastier-Foster, PhD, principal investigator of the BCR.

"Maintaining a key leadership position within TCGA continues Nationwide Children's rising role in the cancer research community. This selection was in recognition of our more than 20 years of expertise in banking tumor specimens and genetic testing of pediatric cancers," explained John Barnard, MD, president, The Research Institute at Nationwide Children's Hospital. "It is a clear example of the trust and satisfaction the NCI has placed in our capabilities."

The BCR contract extends the previous tissue processing and banking work performed at Nationwide Children's Hospital. Since 1989, pediatric tumor specimens from all pediatric institutions in the Children's Cancer Study Group (now part of the Children's Oncology Group, or COG) have been banked at Nationwide Children's Biopathology Center. Because of this expertise and experience, in 1993 Nationwide Children's began working with the Gynecologic Oncology Group (GOG) serving as a biorepository for gynecologic cancer specimens, thus housing two of the NIH's 11 national biospecimen banks.

Today, the Biopathology Center stores more than one million specimens with clinical annotations for use in cancer research, making the hospital one of the largest biorepositories in North America, with expertise in both pediatric and adult tissue specimens. In addition, the Biopathology Center serves as a national reference laboratory for several pediatric cancers, performing genetic testing used to assign patients to tailored therapy. Significant use of the banks by COG and GOG has led to numerous studies and peer-reviewed publications.

"The additional funding from the NCI highlights our initial success as a BCR and expands our opportunity to have a significant national impact on cancer diagnosis and treatment, as well as an immediate impact on our local economy," stated Steve Allen, MD, CEO of Nationwide Children's Hospital.

Since establishing the BCR at Nationwide Children's, more than 40 full-time jobs have been created in areas such informatics, laboratory technology, and clinical trials development. An additional 15 jobs are expected to be added.


'/>"/>

Contact: Pam Barber
Pam.Barber@NationwideChildrens.org
614-355-0495
Nationwide Children's Hospital
Source:Eurekalert

Related biology news :

1. Researchers nationwide ask for new focus on sudden death heart disorder
2. $7 million grant designates Nationwide Childrens as Wellstone Center
3. Hygienic Lab at U. Iowa first to confirm salmonella in nationwide outbreak
4. Allscripts and Sandata Partner to Enhance Quality in Home Care Agencies Nationwide
5. DOE awards UGA $3.1 million to support complex carbohydrate study nationwide
6. 3 new informatics pilot projects to aid clinical and translational scientists nationwide
7. identiMetrics & BIO-key(R) Provide Biometric Finger Scanning for School Food Service Nationwide
8. Childrens Hospital LA discovers growth factor essential to epicardial cell function
9. Tennis stars hospitalization for altitude sickness
10. Massachusetts General Hospitals Warren Triennial Prize to honor pioneers of cellular reprogramming
11. Epilepsy researcher at the Childrens Hospital of Philadelphia receives scientific prize
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2016)... -- As part of its longstanding mission to improve genetic literacy ... released its latest children,s book, titled The One ... topics of inheritance and variation of traits that are part ... school classrooms in the US. The book ... Killoran , whose previous book with 23andMe, You ...
(Date:12/19/2016)... , España y TORONTO , 19 de diciembre ... Northern Biologics Inc. que permitirá el desarrollo acelerado de MSC-1, un ... en varios tipos de tumor en 2017, con múltiples sitios previstos ... ... clase con objetivo en el factor inhibidor de leucemia (LIF), una ...
(Date:12/15/2016)... VANCOUVER, Canada and BADEN-BADEN, Germany ... Solutions, a leading global financial services provider, today announced an ... in passive behavioural biometrics, to join forces. The partnership will ... fraud mitigation strategies in compliance with local data protection regulation. ... In ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... , Jan. 18, 2017  Caris Life Sciences, ... Lustgarten Foundation, the largest private funder of pancreatic ... trial evaluating the impact of immunotherapy in the ... trial enrollment services to identify potential trial candidates ... between treating physicians and study investigators. The Lustgarten ...
(Date:1/17/2017)... Foreside, Maine (PRWEB) , ... January 17, 2017 ... ... announce the addition of Rheumatoid Factor (RF) to its VALIDATE® SP2 calibration verification ... Rheumatoid Factor in a human serum base. Each VALIDATE® SP2 kit is prepared ...
(Date:1/17/2017)... , Jan. 17, 2017  An international team ... Medicine and St. Boniface Hospital Albrechtsen Research Centre/University ... neuropathy, an unmet health need affecting nearly one ... of Clinical Investigation, their results identify small molecule ... and reverse neuronal injury in animal models of ...
(Date:1/17/2017)... LEXINGTON, Mass. , Jan. 17, 2017   ... clinical stage biopharmaceutical company developing innovative inhaled therapies to ... candidate for treating fungal infections in the lungs of ... Infectious Disease Product" (QIDP) by the U.S. Food & ... , which is designed to speed the development of ...
Breaking Biology Technology: