Navigation Links
National Institutes of Health award Williams professor $217,710 research grant
Date:7/10/2008

WILLIAMSTOWN, Mass., July 10, 2008 -- Thomas E. Smith, associate professor of chemistry at Williams College, has been awarded a $217,710 three-year grant by the National Cancer Institute of the National Institute of Health (NIH) for "Asymmetric Methods for the Synthesis of Pyran-Based Anticancer Natural Products."

"This research is concerned with the development of new methods that will allow for the efficient preparation of anticancer compounds," said Smith. He and his team will examine several natural products of promising medicinal value to formulate an efficient general strategy for the asymmetric synthesis of these types of complex molecular architectures.

The molecules that will be examined are acutphycin, which inhibits the growth of malignant cells; tedanolide C, which exhibits potent cytotoxicity against cancer cell lines; and other novel natural products of marine origin.

This study will build on Smith's earlier work on pyran-based products, which was funded by a 2003 National Science Foundation (NSF) grant. Chiral pyran-based ring systems (six-membered rings composed of carbon and oxygen atoms) are found in numerous biologically relevant natural product classes.

At Williams since 1998, Smith teaches courses on the evolution and operation of human medicines, synthetic organic chemistry, and introductory organic chemistry. His research is concerned with organic synthesis and its applications in biology and pharmacology.

Smith's findings on organic synthesis appear in a number of chemistry journals and academic publications, most recently the Journal of Organic Chemistry, Organic Letters, and the Journal of Chemical Education.


'/>"/>

Contact: Jo Procter
Jo.Procter@williams.edu
413-597-4279
Williams College
Source:Eurekalert

Page: 1

Related biology news :

1. Wolves find happy hunting grounds in Yellowstone National Park
2. BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo
3. ESMO International Symposium on Immunology
4. Story tips from the US Department of Energys Oak Ridge National Laboratory, September 2007
5. Office of the Director of National Intelligence, CIO to Speak at Government Security Conference
6. Director of National Intelligence to Speak at Conference
7. Singapore National Science and Technology Awards
8. Conservation International and Toyota partner to protect Philippines rain forests
9. International team shows mercury concentrations in fish respond quickly to increased deposition
10. International team shows mercury concentrations in fish respond quickly to increased deposition
11. Office of the Director of National Intelligence, CIO to Speak at Government Security Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... (NYSE: DAL ) customers now can use fingerprints instead of ... Airport (DCA). ... Delta launches biometrics to board aircraft at Reagan Washington National Airport ... Delta,s biometric boarding pass experience that launched in May ... boarding process to allow eligible Delta SkyMiles Members who are enrolled in ...
(Date:6/14/2017)... June 15, 2017  IBM (NYSE: IBM ) is introducing ... event dedicated to developing collaboration between startups and global businesses, ... 15-17. During the event, nine startups will showcase the solutions ... various industries. France ... market, with a 30 percent increase in the number of ...
(Date:5/16/2017)... , May 16, 2017   Bridge ... health organizations, and MD EMR Systems , ... development partner for GE, have established a partnership ... Portal product and the GE Centricity™ products, including ... EMR. These new integrations will ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... Disappearing forests ... the lives of over 5.5 million people each year. Especially those living in larger ... startup Treepex - based in one of the most pollution-affected countries globally - decided ...
(Date:10/10/2017)... ... ... San Diego-based team building and cooking events company, Lajollacooks4u, has unveiled a ... new look is part of a transformation to increase awareness, appeal to new markets ... It will also expand its service offering from its signature gourmet cooking classes and ...
(Date:10/10/2017)... ... ... Dr. Bob Harman, founder and CEO of VetStem Biopharma, Inc. spent ... entitled “Stem Cells and Their Regenerative Powers,” was held on August 31st, 2017 ... joined by two human doctors: Peter B. Hanson, M.D., Chief of Orthopedic Surgery, Grossmont ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... business process optimization firm for the life sciences and healthcare industries, announces a ... in San Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” ...
Breaking Biology Technology: