Navigation Links
National Institutes of Health award Williams professor $217,710 research grant
Date:7/10/2008

WILLIAMSTOWN, Mass., July 10, 2008 -- Thomas E. Smith, associate professor of chemistry at Williams College, has been awarded a $217,710 three-year grant by the National Cancer Institute of the National Institute of Health (NIH) for "Asymmetric Methods for the Synthesis of Pyran-Based Anticancer Natural Products."

"This research is concerned with the development of new methods that will allow for the efficient preparation of anticancer compounds," said Smith. He and his team will examine several natural products of promising medicinal value to formulate an efficient general strategy for the asymmetric synthesis of these types of complex molecular architectures.

The molecules that will be examined are acutphycin, which inhibits the growth of malignant cells; tedanolide C, which exhibits potent cytotoxicity against cancer cell lines; and other novel natural products of marine origin.

This study will build on Smith's earlier work on pyran-based products, which was funded by a 2003 National Science Foundation (NSF) grant. Chiral pyran-based ring systems (six-membered rings composed of carbon and oxygen atoms) are found in numerous biologically relevant natural product classes.

At Williams since 1998, Smith teaches courses on the evolution and operation of human medicines, synthetic organic chemistry, and introductory organic chemistry. His research is concerned with organic synthesis and its applications in biology and pharmacology.

Smith's findings on organic synthesis appear in a number of chemistry journals and academic publications, most recently the Journal of Organic Chemistry, Organic Letters, and the Journal of Chemical Education.


'/>"/>

Contact: Jo Procter
Jo.Procter@williams.edu
413-597-4279
Williams College
Source:Eurekalert

Page: 1

Related biology news :

1. Wolves find happy hunting grounds in Yellowstone National Park
2. BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo
3. ESMO International Symposium on Immunology
4. Story tips from the US Department of Energys Oak Ridge National Laboratory, September 2007
5. Office of the Director of National Intelligence, CIO to Speak at Government Security Conference
6. Director of National Intelligence to Speak at Conference
7. Singapore National Science and Technology Awards
8. Conservation International and Toyota partner to protect Philippines rain forests
9. International team shows mercury concentrations in fish respond quickly to increased deposition
10. International team shows mercury concentrations in fish respond quickly to increased deposition
11. Office of the Director of National Intelligence, CIO to Speak at Government Security Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... , July 20, 2017 Delta (NYSE: DAL ... board any Delta aircraft at Reagan Washington National Airport (DCA). ... Delta launches biometrics to ... Delta,s biometric ... Sky Club is now integrated into the boarding process to allow ...
(Date:5/23/2017)... robotic gym for the rehabilitation and functional motor sense evaluation of lower ... . The first 30 robots will be available from June in ... The technology was developed and patented at the IIT laboratories and has ... to a 10 million euro investment from entrepreneur Sergio Dompè. ... ...
(Date:4/24/2017)... -- Janice Kephart , former 9/11 Commission ... LLP (IdSP) , today issues the following statement: ... 6, 2017 Executive Order: Protecting the Nation ... instilled with greater confidence, enabling the reactivation of ... are suspended by until at least July 2017). ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... and OXFORD, England , Aug. 16, ... consortium for biotech executive search and leadership development, and Virdis ... sectors, have created an exclusive alliance that enables clients to ... "For our clients here in the ... unparalleled access to a diverse population of leadership talent throughout ...
(Date:8/15/2017)... Boston, MA (PRWEB) , ... August 15, 2017 , ... ... unmet need that has compromised these disciplines for more than half a century. ... cannot be counted. It is widely known that molecular tags developed for this ...
(Date:8/14/2017)... (PRWEB) , ... August 14, 2017 , ... ... characterized and performing antibodies. Key researchers in the antibody community have recently come ... and consistency for antibodies in the laboratory. , The team at ...
(Date:8/11/2017)... ... ... Algenist continues to disrupt the skincare industry with today’s debut of GENIUS ... is the key structural element skin needs to maintain its youthful appearance and Algenist ... First to market with proprietary collagen water active , ...
Breaking Biology Technology: