Navigation Links
Nanotube-based sensors can be implanted under the skin for a year
Date:11/3/2013

CAMBRIDGE, MA -- Nitric oxide (NO) is one of the most important signaling molecules in living cells, carrying messages within the brain and coordinating immune system functions. In many cancerous cells, levels are perturbed, but very little is known about how NO behaves in both healthy and cancerous cells.

"Nitric oxide has contradictory roles in cancer progression, and we need new tools in order to better understand it," says Michael Strano, the Carbon P. Dubbs Professor of Chemical Engineering at MIT. "Our work provides a new tool for measuring this important molecule, and potentially others, in the body itself and in real time."

Led by postdoc Nicole Iverson, Strano's lab has built a sensor that can monitor NO in living animals for more than a year. The sensors, described in the Nov. 3 issue of Nature Nanotechnology, can be implanted under the skin and used to monitor inflammation a process that produces NO. This is the first demonstration that nanosensors could be used within the body for this extended period of time.

Such sensors, made of carbon nanotubes, could also be adapted to detect other molecules, including glucose. Strano's team is now working on sensors that could be implanted under the skin of diabetic patients to monitor their glucose or insulin levels, eliminating the need to take blood samples.

Sensors for short and long term

Carbon nanotubes hollow, one-nanometer-thick cylinders made of pure carbon have drawn great interest as sensors. Strano's lab has recently developed carbon nanotube sensors for a variety of molecules, including hydrogen peroxide and toxic agents such as the nerve gas sarin. Such sensors take advantage of carbon nanotubes' natural fluorescence, by coupling them to a molecule that binds to a specific target. When the target is bound, the tubes' fluorescence brightens or dims.

Strano's lab has previously shown that carbon nanotubes can detect NO if the tu
'/>"/>

Contact: Sarah McDonnell
s_mcd@mit.edu
617-253-8923
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Technical Program Announced for TSensors (Trillion Sensor) Summit at Stanford University for October 22-25, 2013
2. Sensors allow for efficient irrigation, give growers more control over plant growth
3. Butterfly wings inspire new technologies: from fabrics and cosmetics to sensors
4. Nanosensors could aid drug manufacturing
5. Silicon-based Fingerprint Sensors - Global Strategic Business Report
6. Breakthrough: Sensors monitor cells at work
7. Small, portable sensors allow users to monitor exposure to pollution on their smart phones
8. Integrated Biometrics Introduces Sherlock The Worlds Lightest, Thinnest, Smallest, Appendix F Mobile ID Fingerprint Sensors
9. Exclusive agreement to distribute Affinity Biosensors Archimedes system extends Malvern Instruments biopharma solutions
10. Researchers develop method to grow artificial tissues with embedded nanoscale sensors
11. Boston subway system to be used to test new sensors for biological agents
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... of biomedical engineering at the University of Houston, ... and artificial organ development., "Introduction to Tissue Engineering: ... entering into the field of artificial organ development. ... engineering at UH, served as a series editor ... are other published books on the subject of ...
(Date:7/25/2014)... (NRG1) is a pleiotropic factor characterized by the ... of exons that confer to the protein deeply ... both the myelination occurring during development and the ... nerve: axon degeneration, axon regrowth, remyelination and target ... have discovered that the soluble NRG1 upregulation observed ...
(Date:7/25/2014)... girls reach puberty is influenced by ,imprinted genes,a subset of ... gene. This is the first evidence that imprinted genes ... of this study were published today in the journal ... menarche, is a marker for the timing of puberty in ... varies between girls, is an inherited trait, and is linked ...
Breaking Biology News(10 mins):University of Houston researcher publishes textbook on tissue engineering 2Could age of first period influence development of diseases in older women? 2
... MOConstructing a body is like building a houseif you compromise ... on a cellular level than in the case of epithelial ... from the gut to mammary glands. As long as epithelial ... business of building tissue barriers and constructing ducts goes smoothly. ...
... to the brain could be developed thanks to new research. ... able to regenerate protective sheaths around nerve fibres in the ... myelin, are critical for the quick transmission of nerve signals, ... with multiple sclerosis (MS). The study, by the Universities ...
... to assess the status of dozens of European fish stocks ... are being fished sustainably today and that, given time, those ... Cell Press journal Current Biology on July 18, ... European Union,s Common Fisheries Policy is failing, the researchers say. ...
Cached Biology News:A flip of the mitotic spindle has disastrous consequences for epithelial cells 2A flip of the mitotic spindle has disastrous consequences for epithelial cells 3A flip of the mitotic spindle has disastrous consequences for epithelial cells 4MS research could help repair damage affecting nerves 2European fish stocks poised for recovery 2
(Date:7/25/2014)... , July 25, 2014 /PRNewswire-iReach/ -- Xybion ... consulting for global corporations operating in highly regulated ... its first annual Global User Group Conference, Xybion ... Philadelphia, Pennsylvania at the ... http://photos.prnewswire.com/prnh/20140724/130263 This year,s ...
(Date:7/24/2014)... Gain recognition for leadership and ... the biotech industry. Nominations are now being accepted ... you by the Bio Supply Management Alliance ... management professionals for the past 7 years. , ... Biotech industry – Manufacturers, Service Providers, Material Suppliers, ...
(Date:7/24/2014)... A research team led by group leader Yung-Eun ... technology to synthesize sulfur-doped and nitrogen-doped graphenes which ... secondary batteries and fuel cells. Yung-Eun Sung is ... Nanoparticle Research at Institute for Basic Science* (IBS) ... , This achievement has great significance with regards ...
(Date:7/24/2014)... July 24, 2014 Research and Markets ... Genomics and Proteomics Analytical Instruments Market 2014-2018" report ... Genomics is the study of the ... of the structure and functions of proteomes or sets ... and technology. Genomics involves the mapping of genes and ...
Breaking Biology Technology:Xybion Announces It Will Host International User Conference in Philadelphia 2Xybion Announces It Will Host International User Conference in Philadelphia 3Call for Submission: BSMA’s Supply Chain Management Innovation Awards 2Call for Submission: BSMA’s Supply Chain Management Innovation Awards 3Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific 2
... , , , , , ... Kits and Ser/Thr Kinase , Kit provide fast and ... serine/threonine kinases. LiquiChip 10-Cytokine Kits enable simultaneous , multiplex ... The LiquiChip Ser/Thr Kinase Kit enables highly sensitive assay of kinases , ...
... , The proven activated dendrimer for transfection , of a ... and benefits , , Fast ... cell lines , Transfection in the presence of serum (see figure ... , High transient and stable transfection efficiencies , ...
... , For purification of endotoxin-free ultrapure , plasmid or cosmid DNA , ... , Less than 0.1 EU/g plasmid DNA , ... Greater than 90% recovery of plasmid DNA , Fast and simple ... , , * Actual yields depend on plasmid copy number, size ...
Cached Biology Technology:LiquiChip Kits for bead-based cytokine and kinase assays 2LiquiChip Kits for bead-based cytokine and kinase assays 3SuperFect Transfection Reagent 2SuperFect Transfection Reagent 3EndoFree Plasmid Kits 2EndoFree Plasmid Kits 3EndoFree Plasmid Kits 4
Rabbit polyclonal to ErbB 2 (phospho Y1248) ( Abpromise for all tested applications). entrezGeneID: 2064 SwissProtID: P04626...
The Microseal 384 plate positioner ensures precise positioning of Microseal 384-well plates in the x-, y-, and z-dimensions, for accurate automated liquid handling....
... This thin foil heat sealing material ... pressure from a screw down heated ... is a useful method for sample ... over the existing seal. Ideal for ...
... DS-U2 camera controller is the successor to the ... interface any of the cameras in the Nikon ... a USB2.0 interface. The DS-U2 transmits information at ... by equipping both hub and mass storage USB ...
Biology Products: