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Nanotechnology helps track and improve drug action in pancreatic cancer
Date:6/11/2013

r at sub-cellular resolution. We can then see where we need to improve on drug delivery to improve clinical outcome."

It has been hard to treat pancreatic tumours because they are extremely dense with collagen and have poor blood vessel networks for delivering drugs.

Professor Kurt Anderson observed that combination therapies can now be used to break down collagen, weakening tumour architecture and making it easier to get the drugs where they need to be. "The trick is to break down the structure just enough to get the drug in, but not so much that you damage the organ itself," he said.

"These new FRET technologies help us gauge what is just enough and not too much."

"These are very exciting discoveries we now have spatial and temporal information about cancer behaviour that we've never had before, as well as the nanotechnology to monitor and improve drug delivery in hard to reach tumour regions."


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Contact: Alison Heather
a.heather@garvan.org.au
61-292-958-128
Garvan Institute of Medical Research
Source:Eurekalert

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