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Date:7/14/2010

se an object compresses the waveguide, then light can escape at that point. An imager will capture the light and from this image the mechanical properties of the objects may be determined.

In this case, the object in question is a tumor. In the case of the Temple research the waveguide consists of a flexible probe fed with light from a light emitting diode (LED). Light exiting the probe is caught on a camera, and from the emergent light the scientists are able to measure tumor diameters to within about 4 percent and tumor depths to 7.6 percent.

"We have performed a phantom study and [imaged] globus tumors in mice," says Won. "More sophisticated machines such as MRI will measure the size and depth more accurately, but the elasticity information is unavailable with MRI. Conversely, methods such as sonoelastography will provide the elasticity information, but this is a much more complex machine. Our device provides a means of detecting size, depth, and elasticity information in a relative simple device."

The next step, Won says, is to move from imaging mouse to human tumors with the device. This he is now doing with collaborators at the Thomas Jefferson University Hospital and Cooper University Hospital.

Small-scale human tests will be carried out within this year. Won says that this device has a potential to be used in breast cancer screening if it proves successful.

A website with more information: http://www.temple.edu/csnap/

The presentation "Design and Evaluation of an Optical Tactile Imaging Device for Tumor Detection" by C Won et al. will be at 3:00 p.m. on Sunday, July 18 in the exhibit hall of the Philadelphia Convention Center.

ABSTRACT: http://www.aapm.org/meetings/amos2/pdf/49-13673-56966-519.pdf

6) MAKING TUMORS GLOW COULD REVEAL THEIR HIDING SPOTS

Getting a clear picture of a hidden tum
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Contact: Jason Socrates Bardi
jbardi@aip.org
858-775-4080
American Institute of Physics
Source:Eurekalert

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