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Date:7/14/2010

that would enable them to circulate through the human body and attach to cancer cells. Radiation from a CT scanner could then light them up, and this light -- generally harmless to the human body -- would be detected by a simple CCD camera.

Because infrared light tends to be absorbed by the body, these crystals may one day be most useful in a clinical setting for imaging shallow tissues or for organs that can be reached with a fiber optic cable that can detect the light.

"If light is not coming out of the subject, if the tissue is deep, you could go in with an endoscope to detect it," said Pratx. "You could possibly use this for prostate or colorectal cancer imaging."

Pratx has successfully detected the crystals inside of 6-centimeter gelatin cylinders that have optical and X-ray properties similar to those of human tissue, and in cervical cancer cells in a petri dish.

The researchers are now beginning to test the toxicity and effectiveness of these crystals in mice.

The presentation "X-Ray Luminescence Computed Tomography Via Selective X-Ray Excitation" by G Pratx et al. will be at 4:00 p.m. on Monday, July 19 in room 204C of the Philadelphia Convention Center.

ABSTRACT: http://www.aapm.org/meetings/amos2/pdf/49-13905-2259-485.pdf


14) MORE MEETING INFORMATION

The presentations at the AAPM meeting will cover topics ranging from new ways of imaging the human body to the latest clinical developments on treating cancer with high energy X-rays and electrons from accelerators, brachytherapy with radioactive sources, and protons. Many of the talks and posters are focused on patient safety -- tailoring therapy to the specific needs of people undergoing treatment, such as shaping emissions to conform to tumors, or finding ways to image children safely at lower radiation exposures while maintaining good image quality.'/>"/>

Contact: Jason Socrates Bardi
jbardi@aip.org
858-775-4080
American Institute of Physics
Source:Eurekalert

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