Navigation Links
Nanotech device mimics dog's nose to detect explosives

(Santa Barbara, CA ) Portable, accurate, and highly sensitive devices that sniff out vapors from explosives and other substances could become as commonplace as smoke detectors in public places, thanks to researchers at University of California, Santa Barbara.

Researchers at UCSB, led by professors Carl Meinhart of mechanical engineering and Martin Moskovits of chemistry, have designed a detector that uses microfluidic nanotechnology to mimic the biological mechanism behind canine scent receptors. The device is both highly sensitive to trace amounts of certain vapor molecules, and able to tell a specific substance apart from similar molecules.

"Dogs are still the gold standard for scent detection of explosives. But like a person, a dog can have a good day or a bad day, get tired or distracted," said Meinhart. "We have developed a device with the same or better sensitivity as a dog's nose that feeds into a computer to report exactly what kind of molecule it's detecting." The key to their technology, explained Meinhart, is in the merging of principles from mechanical engineering and chemistry in a collaboration made possible by UCSB's Institute for Collaborative Biotechnologies.

Results published this month in Analytical Chemistry show that their device can detect airborne molecules of a chemical called 2,4-dinitrotoluene, the primary vapor emanating from TNT-based explosives. The human nose cannot detect such minute amounts of a substance, but "sniffer" dogs have long been used to track these types of molecules. Their technology is inspired by the biological design and microscale size of the canine olfactory mucus layer, which absorbs and then concentrates airborne molecules.

"The device is capable of real-time detection and identification of certain types of molecules at concentrations of 1 ppb or below. Its specificity and sensitivity are unparalleled," said Dr. Brian Piorek, former mechanical engineering doctoral student in Meinhart's laboratory and Chief Scientist at Santa Barbara-based SpectraFluidics, Inc. The technology has been patented and exclusively licensed to SpectraFluidics, a company that Piorek co-founded in 2008 with private investors.

"Our research project not only brings different disciplines together to develop something new, but it also creates jobs for the local community and hopefully benefits society in general," commented Meinhart.

Packaged on a fingerprint-sized silicon microchip and fabricated at UCSB's state-of-the-art cleanroom facility, the underlying technology combines free-surface microfluidics and surface-enhanced Raman spectroscopy (SERS) to capture and identify molecules. A microscale channel of liquid absorbs and concentrates the molecules by up to six orders of magnitude. Once the vapor molecules are absorbed into the microchannel, they interact with nanoparticles that amplify their spectral signature when excited by laser light. A computer database of spectral signatures identifies what kind of molecule has been captured.

"The device consists of two parts," explained Moskovits. "There's a microchannel, which is like a tiny river that we use to trap the molecules and present them to the other part, a mini spectrometer powered by a laser that detects them. These microchannels are twenty times smaller than the thickness of a human hair."

"The technology could be used to detect a very wide variety of molecules," said Meinhart. "The applications could extend to certain disease diagnosis or narcotics detection, to name a few."

Moskovits added, "The paper we published focused on explosives, but it doesn't have to be explosives. It could detect molecules from someone's breath that may indicate disease, for example, or food that has spoiled."

The fundamental research was developed through an interdisciplinary collaboration between Professors Meinhart and Moskovits, and carried out by former doctoral researchers Dr. Piorek and Dr. Seung-Joon Lee. Their project was funded in part by UCSB's Institute for Collaborative Biotechnologies through the Army Research Office and DARPA.

Contact: Melissa Van De Werfhorst
University of California - Santa Barbara

Related biology news :

1. European boost for DNA nanotechnology
2. Mercury in water, fish detected with nanotechnology
3. Realizing the promise of RNA nanotechnology for new drug development
4. New study shows promise in using RNA nanotechnology to treat cancers and viral infections
5. Understanding the biological and ecological implications of safe nanotechnology
6. Nanotechnology breakthrough could dramatically improve medical tests
7. New study shows how nanotechnology can help detect disease earlier
8. Purdue professor to speak before Congress about nanotechnology in brain treatment research
9. Simplifying heart surgery with stretchable electronics devices
10. Stryker Chooses Wineman Technology for Medical Device Test Equipment and Software
11. Medical devices powered by the ear itself
Post Your Comments:
Related Image:
Nanotech device mimics dog's nose to detect explosives
(Date:11/17/2015)... PARIS , November 17, 2015 ... November 2015.   --> Paris from ... --> DERMALOG, the biometrics innovation leader, has invented the ... and fingerprints on the same scanning surface. Until now two ... fingerprints. Now one scanner can capture both on the same ...
(Date:11/17/2015)...  Vigilant Solutions announces today that Mr. Dick ... --> --> Mr. ... partnership at TPG Capital, one of the largest global ... in revenue.  He founded and led TPG,s Operating Group, ... from 1997 to 2013.  In his first role, he ...
(Date:11/16/2015)... , Nov 16, 2015  Synaptics Inc. ... human interface solutions, today announced expansion of its ... ™ touch controller and display driver integration ... of smartphones. These new TDDI products add to ... (HD resolution), TD4302 (WQHD resolution), and TD4322 (FHD ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... ... November 30, 2015 , ... ... join physicians, aesthetic practitioners and aesthetics professionals from Central America and abroad for ... held in Panama City, Panama Feb. 17-19, 2016. Testart will present and discuss ...
(Date:11/30/2015)... /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ), a leader in ... Business Act on Climate Pledge, alongside more than 140 companies ... Obama Administration to demonstrate an ongoing commitment to climate action ... COP21 Paris climate negotiations. ... Canada . --> BioAmber uses biotechnology to ...
(Date:11/30/2015)... 30, 2015 Spherix Incorporated (Nasdaq: ... the fostering and monetization of intellectual property, today ... initiatives designed to create shareholder value. ... Spherix. "Based on published reports, the total addressable ... billion and Spherix will seek to secure fair ...
(Date:11/30/2015)... -- HUYA Bioscience International, the leader in accelerating global development ... announced it has signed a Memorandum of Understanding with ... between KDDF and HUYA with the ultimate goal of ... the global market. China,s ... preclinical and clinical stage compounds. The company advances the ...
Breaking Biology Technology: