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Nanostructures with living cells
Date:2/5/2013

This press release is available in German.

The behavior of cells strongly depends on their environment. If they are to be researched an manipulated, it is crucial to embed them in suitable surroundings. Aleksandr Ovsianikov is developing a laser system, which allows living cells to be incorporated into intricate taylor-made structures, similar to biological tissue, in which cells are surrounded by the extracellular matrix. This technology is particularly important for artificially growing biotissue, for finding new drugs or for stem cell research. Ovsianikov has now been awarded the ERC Starting Grant from the European Research Council (ERC) of approximately 1.5 million Euros.

High-Tech-Structures for Biomedical Research

"Growing cells on a flat surface is easy, but such cell cultures often behave differently from the cells in a real three dimensional tissue", says Aleksandr Ovsianikov. While in two dimensions, conventional Petri dishes are used, no standard system has yet been available for three dimensional cell cultures. Such a 3D-matrix needs to be porous, so that the cells can be supplied with all the necessary nutrients. Furthermore, it is important that the geometry, chemical and mechanical parameters of this matrix can be precisely adjusted in order to study and induce necessary cell responses. Also, it is important that the structure can be produced quickly and in large quantities, as biological experiments usually have to be carried out in many cell cultures at the same time to yield reliable data.

These requirements are met very well by the research group "Additive Manufacturing Technologies" at the Vienna University of Technology. The interdisciplinary team of researchers has been developing special technologies to create three dimensional structures with precision on a sub-micrometer scale. "We want to deve
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Contact: Florian Aigner
florian.aigner@tuwien.ac.at
0043-158-801-41027
Vienna University of Technology
Source:Eurekalert  

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