Navigation Links
Nanomedicine: Ending 'hit and miss' design
Date:12/10/2009

HOUSTON -- (Dec. 10, 2009) -- One of the promises of nanomedicine is the design of tiny particles that can home in on diseased cells and get inside them. Nanoparticles can carry drugs into cells and tag cells for MRI and other diagnostic tests; and they may eventually even enter a cell's nucleus to repair damaged genes. Unfortunately, designing them involves as much luck as engineering.

"Everything in nanomedicine right now is hit-and-miss as far as the biological fate of nanoparticles," said Rice University bioengineering researcher Jennifer West. "There's no systematic understanding of how to design a particle to accomplish a certain goal in terms of where it goes in a cell or if it even goes into a cell."

West's lab and 11 others in the Texas Medical Center -- including three at Rice's BioScience Research Collaborative -- are hoping to change that, thanks to a $3 million Grand Opportunity (GO) grant from the National Institutes of Health. NIH established the GO grant program with funding from the American Recovery and Reinvestment Act (ARRA).

One problem facing scientists today is that nanoparticles come in many shapes and sizes and can be made of very different materials. Some nanoparticles are spherical. Others are long and thin. Some are made of biodegradable plastic and others of gold, carbon or semiconducting metals. And sometimes size -- rather than shape or material -- is all-important.

West demonstrates this using a video on her computer that was created by Rice GO grant investigator Junghae Suh. The movie was created by snapping an image with a microscope every few seconds. In the video, dozens of particles move about inside a cell. Half of the particles are tagged with a red fluorescent dye and move very slowly. The rest are green and zip from place to place.

"These are made of the same material and have the same chemistry," said West, Rice's Isabel C. Cameron Professor and department chair of Bioenginee
'/>"/>

Contact: Jade Boyd
jadeboyd@rice.edu
713-348-6778
Rice University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. National Institutes of Health Secures Armory with Patent-Pending Technology
2. New strategy for mending broken hearts?
3. Transport behavior of E. coli varies depending on manure source
4. VCU survey: US public supports genetic research, testing and government spending on research
5. MIT: Mending broken hearts with tissue engineering
6. Nitrous oxide emissions respond differently to no-till depending on the soil type
7. Extending the life of fresh cranberries
8. Coastal management cooperation, enforcement key to avoid pending crisis for millions: UN experts
9. Coastal management cooperation, enforcement key to avoid pending crisis for millions: U.N. experts
10. New research suggests biofuel blending is often inaccurate
11. Stanford researchers say climate change will significantly increase impending bird extinctions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2015)... May 21, 2015 According ... Market by Solutions (Hardware, Software, Services), by Applications (Surveillance ... others), by End-Users (Military & Defense & Commercial) ... Thermal Imaging Market is expected to grow from ... 2020, at a Compound Annual Growth Rate (CAGR) ...
(Date:5/19/2015)... Sweden , May 18, 2015 ... fingerprint sensors FPC1020, FPC1025, FPC1145, FPC1155 and FPC1035 from one ... from June until and including Q3 2015 and the sensors ... . Communicated order values for 2015 hereby amount to ... for Q1 2015 of 140 MSEK and a number of ...
(Date:5/14/2015)... Research and Markets ( http://www.researchandmarkets.com/research/5whpxg/fingerprint ) ... Market in Smart Mobile Devices " report to ... was a watershed year for fingerprint sensors in smartphones ... Apple gave fingerprint sensors a raison d,etre in the ... are a must-have feature in flagship smartphones. ...
Breaking Biology News(10 mins):Thermal Imaging Market Worth $9,998.9 Million by 2020 2Thermal Imaging Market Worth $9,998.9 Million by 2020 3Thermal Imaging Market Worth $9,998.9 Million by 2020 4Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Global Smart Mobile Devices Fingerprint Sensors Market 2015-2019: Key Vendors are Authentec, Validity Sensors, Fingerprint Cards, Next Biometrics Group. IDEX, and Qualcomm 2
... have eyes sensitive to ultraviolet light, which they may use ... a new Nova Southeastern University study suggests. Tamara Frank, ... University,s Oceanographic Center, who is the principal investigator of the ... pitch dark area at the ocean bottom ---- may be ...
... Sorting good data from bad is critical when analyzing ... researchers at Rice University. The trick is to find ... A new paper by the Rice lab ... bioengineering, offers a methodology to optimize the sensitivity of ...
... 0.3 percent of the world,s water supply can be ... the world population is growing steadily, thus increasing the ... as reverse osmosis will be instrumental in ensuring that ... membrane filtration system removes substances such as salts, pesticides, ...
Cached Biology News:Deep-sea crabs seek food using ultraviolet vision 2Deep-sea crabs seek food using ultraviolet vision 3Rice University researchers optimize photoluminescent probes to study DNA and more 2Rice University researchers optimize photoluminescent probes to study DNA and more 3Turning ideas into products faster 2Turning ideas into products faster 3
(Date:5/27/2015)... VANCOUVER , May 27, 2015 /CNW/ - CQDM, ... award close to $8.5M to six (6) multi-disciplinary and ... in neuroscience within their Focus on Brain strategic initiative. ... research entities involved as in-kind contributions. This exciting announcement ... Canadian Association for Neuroscience in the presence of Inez ...
(Date:5/27/2015)... 27, 2015 The ALS Therapy ... its wholly owned subsidiary, Anelixis Therapeutics , $1.5 ... ALS that targets the innate immune system. The funding ... Institute received from the 2014 social media phenomenon known ... of $4 million raised directly by the Institute through ...
(Date:5/27/2015)... FRANCISCO, Calif. , May 27, 2015 /PRNewswire/ ... the treatment of cancer, today announced the appointments ... officer and Cynthia Ladd as senior ... CytomX, Goeltz was chief financial officer of Onyx ... as an independent consultant and legal counsel to ...
(Date:5/27/2015)... Calif. , May 27, 2015  Two years ... biotech professionals, hackers and citizen scientists, Oakland ... $30,000 crowdfunding campaign promoting its mission to democratize science ... Temescal District. ... Based out of ...
Breaking Biology Technology:Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 2Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 3Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 4Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 5Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 6Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 7Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 8Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 9Focus on Brain: $10M for breakthrough technologies to address unmet needs in neurosciences 10Ice Bucket Challenge Advances Antibody Toward Clinical Trial for ALS 2Ice Bucket Challenge Advances Antibody Toward Clinical Trial for ALS 3CytomX Expands Executive Leadership Team 2CytomX Expands Executive Leadership Team 3East Bay's Counter Culture Labs Seeks to Open Doors of Science to Public 2East Bay's Counter Culture Labs Seeks to Open Doors of Science to Public 3
... ),announced today that Judge Jamie D. Happas of the New ... summary judgment in two,hormone therapy cases that were scheduled for ... v. Wyeth, which was to have begun on,September 15, and ... The,plaintiffs in both cases alleged they developed breast cancer as ...
... Vermillion, Inc.,(Nasdaq: VRML ), a molecular ... LLC., a global, growth-company investment bank, to,assist the ... enhance the potential of the Company,s proteomic tests,(OVA1(TM) ... stockholder value. No assurances can be given that ...
... 14 NuVasive, Inc. (Nasdaq:,NUVA), a medical device company ... the spine, announced today,details relating to its second quarter ... 24, 2008 after the close of the market., ... 24, 2008 at 5:30,p.m. ET / 2:30 p.m. PT ...
Cached Biology Technology:Vermillion Retains ThinkPanmure to Assist in the Evaluation of Potential Strategic Alternatives 2NuVasive Announces Web Cast and Conference Call of Second Quarter 2008 Results 2NuVasive Announces Web Cast and Conference Call of Second Quarter 2008 Results 3
The Bio-Plex Manager version 3.0 to 4.0 workstation software upgrade kit is used to upgrade existing Bio-Plex Manager version 3.0 software to version 4.0 security edition software....
... --- a cocktail of 3 siRNAs specifically ... our most popular product. The siTrio reagent ... of your target gene when used under ... and confirmation of optimal transfection with one ...
... Spring offers a large collection of ... fetal tissuea, cell lines, and mouse ... in pHD9 vector. The size of ... be from 200bp to 1000bp by ...
... #27295 has improved stability and convenience from the ... only has overcome this problem but also produced ... changed the formulation of HRP conjugated antibody from ... this change, the stability of the conjugate has ...
Biology Products: