Navigation Links
Nanoengineers aim to grow tissues with functional blood vessels
Date:11/15/2010

University of California, San Diego NanoEngineers won a grant from the National Institutes of Health (NIH) to develop the tools to manufacture biodegradable frames around which heart tissues functional blood vessels included will grow. Developing methods for growing tissues that mimic nature's fine-grained details, including vasculature, could lead to breakthroughs in efforts to grow replacement cardiac tissues for people who have suffered a heart attack. The work could also lead to better systems for growing and studying cells, including stem cells, in the laboratory.

Professor Shaochen Chen from the UC San Diego Department of NanoEngineering is the Principal Investigator on the four-year $1.5 million grant from the National Institutes of Health. The grant is funding development of the manufacturing platform necessary to produce these biodegradable frames or "scaffolds."

"We are creating biomaterials with nanostructures on the inside," said Chen. "Scientifically there are so many opportunities at the molecular level, and nanoengineering is a perfect fit for that. We expect our new biofabrication platform will yield tissues that mimic natural tissues much more closely."

One such opportunity is to add new levels of precision and functionality to the scaffolds produced by the "biofabrication platform" that Chen and his collaborators invented and have been improving over the last five years.

With the improved biofabrication platform, engineers in the Department of NanoEngineering within the UC San Diego Jacobs School of Engineering will be able to produce scaffolds with precisely designed systems of nanoscale pores and other microarchitectural details that control how cells interact with each other and with the environment.

"You need to design the pores so the cell can get nutrition and dump wastepathways for the cell to survive in the system," explained Chen.

The researchers also plan to create scaffolds
'/>"/>

Contact: Daniel Kane
dbkane@ucsd.edu
858-534-3262
University of California - San Diego
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. The world is not flat: Exploring cells and tissues in three dimensions
2. New insights provide promise for development of tools to protect damaged tissues
3. Green tea component may help preserve stored platelets, tissues
4. A new way to assemble cells into 3-D microtissues
5. UD researchers show that plants can accumulate nanoparticles in tissues
6. Human genes sing different tunes in different tissues
7. Structural defects precede functional decline in heart muscle
8. Mass. General researchers develop functional, transplantable rat liver grafts
9. Compression clothing and athletic performance -- functional or fad?
10. Incorporating biofunctionality into nanomaterials for medical, health devices
11. Multifunctional polymer neutralizes both biological and chemical weapons
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nanoengineers aim to grow tissues with functional blood vessels
(Date:9/16/2014)... pipeline (KXL) would likely increase oil sands extraction, according ... the non-profit organization Near Zero. The results are detailed ... includes both supporters and opponents of the pipeline. ... lead to significantly higher greenhouse gas emissions, with the ... , "This report examines three main scenarios discussed by ...
(Date:9/16/2014)... years after the Hesperides vessel returned to Spain culminating ... have an increasingly clear picture of how the global ... the input of pollutants from the atmosphere is not ... most remote areas of the planet, and it is ... are presented this week in CSIC Residence for Researchers ...
(Date:9/16/2014)... for independence later this week, its Government could face ... fracking is necessary, research has revealed. , The University ... perception of shale gas extraction in the UK since ... of the border are the least supportive of fracking. ... the University,s School of Geography, said: "The clear move ...
Breaking Biology News(10 mins):Keystone XL would likely raise oil sands production and greenhouse gas emissions 2The Malaspina Expedition confirms that pollution reaches even the most remote areas of the ocean 2The Malaspina Expedition confirms that pollution reaches even the most remote areas of the ocean 3Scottish people most sceptical on fracking, survey shows 2Scottish people most sceptical on fracking, survey shows 3
... chief executive officer of DuPont, and Abby Joseph Cohen, ... & Co., will be featured speakers at a University ... to be held Friday, Nov. 2, in Clayton Hall, ... conference is the first in a new series of ...
... of marine microbes have been discovered at two deep-sea ... the MBL (Marine Biological Laboratory) and University of Washingtons ... Their findings, published in the October 5 issue of ... comprehensive, comparative study to date of deep-sea microbial communities ...
... (ESA) is proud to announce its selection of ... as an ESA Fellow acknowledges outstanding contributions in research, ... have have participated actively in ESA affairs and served ... be recognized during the ESA Annual Meeting, which will ...
Cached Biology News:UD hosts conference on knowledge-based partnerships Nov. 2 2Hydrothermal vents: Hot spots of microbial diversity 2Entomological Society of America recognizes 2007 fellows and honorary members 2Entomological Society of America recognizes 2007 fellows and honorary members 3
(Date:9/16/2014)... Longmeadow, MA (PRWEB) September 16, 2014 ... appointment of Brian Highley as CEO of CIRTEC. ... this exciting point for the Company.” noted Brian Highley. ... operational performance while sustaining strong organic growth over the ... CIRTEC’s growth by continuing to improve and expand the ...
(Date:9/16/2014)... N.C. , Sept. 16, 2014  The ... oldest entrepreneurial support organization in the country, today ... Innovators Report . It showed ... North Carolina startups in the ... drew more global investment from a variety of ...
(Date:9/16/2014)... 2014   Synthetic Biologics, Inc. (NYSE ... biologic and drug programs targeting specific pathogens that ... of the Company,s Investor Day in ... bowel syndrome (IBS) program, including its novel, oral ... In the keynote presentation, Mark Pimentel , ...
(Date:9/16/2014)... Pharma Packaging Solutions announced ... for their 89th year in business. Adding ... Packaging Solutions is preparing packaging operations changes ... new procedures. Establishing training and system validation ... Pharma Packaging Solutions will be ready to ...
Breaking Biology Technology:CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 2CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 3CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 4Synthetic Biologics' Statin-Class Candidate for Constipation-Predominant Irritable Bowel Syndrome Detailed at Company's Investor Day 2Synthetic Biologics' Statin-Class Candidate for Constipation-Predominant Irritable Bowel Syndrome Detailed at Company's Investor Day 3Adding Serialization Capabilities and Expanded Capacity, Pharma Packaging Solutions Is Preparing for 89th Year of Business 2
... (Nasdaq: VNDA ), a biopharmaceutical company focused ... for central,nervous system disorders, today announced financial and ... 2008., Vanda reported research and development (R&D) ... million, compared to $5.5 million in the second,quarter ...
... STERIS Corporation,(NYSE: STE ) today announced financial ... 2008. Fiscal 2009 second quarter revenues,increased 10% to $323.1 ... fiscal 2008, driven by strong growth in all three ... million, or $0.48,per diluted share, compared with net income ...
... Genetic Variations Identify Predisposition to Early Cardiovascular,Events in ... Interleukin Genetics,Inc. (Amex: ILI ), announced today ... will present new research findings on,the genetics of ... Symposium (CVGAS), which takes place from Oct. 31 ...
Cached Biology Technology:Vanda Pharmaceuticals Reports Third Quarter 2008 Results 2Vanda Pharmaceuticals Reports Third Quarter 2008 Results 3Vanda Pharmaceuticals Reports Third Quarter 2008 Results 4Vanda Pharmaceuticals Reports Third Quarter 2008 Results 5Vanda Pharmaceuticals Reports Third Quarter 2008 Results 6Vanda Pharmaceuticals Reports Third Quarter 2008 Results 7Vanda Pharmaceuticals Reports Third Quarter 2008 Results 8Vanda Pharmaceuticals Reports Third Quarter 2008 Results 9Vanda Pharmaceuticals Reports Third Quarter 2008 Results 10STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 2STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 3STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 4STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 5STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 6STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 7STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 8STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 9STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 10STERIS Corporation Announces Fiscal 2009 Second Quarter and First Half Results 11Interleukin Genetics to Present New Findings at the 11th Cardiovascular Genomics and Atherosclerosis Symposium 2Interleukin Genetics to Present New Findings at the 11th Cardiovascular Genomics and Atherosclerosis Symposium 3Interleukin Genetics to Present New Findings at the 11th Cardiovascular Genomics and Atherosclerosis Symposium 4
Applications: Western blotting ...
...
... efficiencies and the chemistry of light production ... benefit that they require simple triggering conditions ... This benefit has been exploited to great ... compounds can also be easily modified to ...
ssDNA from PCR DNA in less than 1 hour. No gels, columns, or slurries. Sequence from high quality ssDNA: clearer reads, longer runs....
Biology Products: