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Nanodisk gene therapy
Date:1/11/2011

han if they dispersed passively in the interior. Nanoparticles accumulate in the interior of the nucleus and not in the cytoplasm - the thick liquid between the cell membrane and nucleus - and therefore increase their level of effectiveness. One of the photos was selected by the journal Biomaterials as one of the 12 images of the year 2010.

Participating in this discovery were researchers from the Institute of Material Science of Barcelona (ICMAB-CSIC), the Catalan Institute for Research and Advanced Studies (ICREA), and the Technical University of Catalonia. The discovery represents a new category of nanoparticles offering therapeutic benefits. According to Dr Esther Vzquez, director of the project, "nanodisks assemble automatically, move rapidly, remain stable and travel to the interior of the nucleus. This makes them a promising tool as a prototype for the safe administration of nucleic acids and functional proteins."


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Contact: Antonio Villaverde
antoni.villaverde@uab.cat
34-935-813-086
Universitat Autonoma de Barcelona
Source:Eurekalert

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