Navigation Links
Nanocrystals reveal activity within cells
Date:6/16/2009

Researchers at the U.S. Department of Energy's (DOE) Lawrence Berkeley National Laboratory have created bright, stable and bio-friendly nanocrystals that act as individual investigators of activity within a cell.

These ideal light emitting probes represent a significant step in scrutinizing the behaviors of proteins and other components in complex systems such as a living cell.

Labeling a given cellular component and tracking it through a typical biological environment is fraught with issues: the probe can randomly turn on and off, competes with light emitting from the cell, and often requires such intense laser excitation, it eventually destroys the probe, muddling anything you'd be interested in seeing.

"The nanoparticles we've designed can be used to study biomolecules one at a time," said Bruce Cohen, a staff scientist in the Biological Nanostructures Facility at Berkeley Lab's nanoscience research center, the Molecular Foundry. "These single-molecule probes will allow us to track proteins in a cell or around its surface, and to look for changes in activity when we add drugs or other bioactive compounds."

Molecular Foundry post-doctoral researchers Shiwei Wu and Gang Han, led by Cohen, Imaging and Manipulation of Nanostructures staff scientist Jim Schuck and Inorganic Nanostructures Facility Director Delia Milliron, worked to develop nanocrystals containing rare earth elements that absorb low-energy infrared light and transform it into visible light through a series of energy transfers when they are struck by a continuous wave, near-infrared laser. Biological tissues are more transparent to near-infrared light, making these nanocrystals well suited for imaging living systems with minimal damage or light scatter.

"Rare earths have been known to show phosphorescent behavior, like how the old-style television screen glows green after you shut it off. These nanocrystals draw on this property, and are a million t
'/>"/>

Contact: Aditi Risbud
ASRisbud@lbl.gov
510-486-4861
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. Study begins to reveal clues to the cause and progression of sepsis
3. Comet probes reveal evidence of origin of life, scientists claim
4. Structure of 450 million year old protein reveals evolutions steps
5. UF scientists reveal how dietary restriction cleans cells
6. Neural stem cell study reveals mechanism that may play role in cancer
7. New method reveals substances on surfaces of any kind
8. Study reveals predation-evolution link
9. IDEMA Reveals Program Highlights for DISKCON USA 2007
10. Study reveals possible genetic risk for fetal alcohol disorders
11. IDEMA Reveals Program Highlights for DISKCON USA 2007
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nanocrystals reveal activity within cells
(Date:8/17/2015)...  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market and creator of the Wocket® ... 2015. The new marketing campaign is being spearheaded by ... Group ( http://amplitudemarketing.com/ ) and TPMG ( http://tmpg.com/ ). ... retail driven marketing and brand awareness and has a ...
(Date:8/12/2015)... , Aug. 12, 2015  New research unveiled ... attack Android phones to steal users, fingerprints. Information ... availability of fingerprint scanners on mobile devices, making ... To secure biometrics on mobile devices, HYPR Corp. ... these convenient authentication systems with strong cryptographic security. ...
(Date:8/10/2015)... and TELTOW, Germany , August 10, ... (SMI), a world leader in Eye Tracking Technology for ... its OEM Eye Tracking Platform for integration into all ... contains reference designs for seamless integration of eye tracking ... reality HMDs and augmented reality smart glasses. Omnivision,s leading ...
Breaking Biology News(10 mins):NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 2NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 3HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 2HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 3SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3
... has been identified by a team of scientists, including a ... treatments for those affected by the conditions brought on by ... and studying the gene in zebrafish embryos, and the team,s ... genetics of mice and people. "This work really ...
... U.S. Fish and Wildlife Service is excluding significant research ... even when the law governing the agency,s actions requires ... species need protection from extinction. A group of ... argue in the December issue of the journal ...
... NY) ─ Scientists at Albert Einstein College of ... finding about the method by which certain genes are ... that work with other genes to build protein structures ... are turned on randomly. The surprising discovery, described in ...
Cached Biology News:Scientists find gene linked to congenital heart defect 2Scientists find gene linked to congenital heart defect 3Scientists find gene linked to congenital heart defect 4Researchers: Include data about societal values in endangered species decisions 2Researchers: Include data about societal values in endangered species decisions 3Researchers: Include data about societal values in endangered species decisions 4Study of how genes activate yields surprising discovery 2Study of how genes activate yields surprising discovery 3
(Date:9/2/2015)... Biovista Inc. freut sich, ... 2015 bekanntgeben zu können. Hierbei handelt es sich ... Biovista unterstützt mit seiner Möglichkeit der Analyse ... Krankheiten als denen, für die ein Medikament ursprünglich ... Team bei der Wylder Nation Foundation bei der ...
(Date:9/2/2015)... ... , ... Temarry Recycling's new $100,000 waste to energy capital ... continue to contribute to the sustainability of our natural resources. , Waste to ... been operating at their Mexico facility, Recicladora Temarry, for the last 7 years. ...
(Date:9/1/2015)... Swecure, ein Biotechnologieunternehmen, ... Entwicklung neuartiger Therapien für Störungen des Immunsystems ... konzentriert, erhält vom US Patent and Trademark ... patentiert wird. Das Medikament basiert auf einem ... und Entzündungen vorbeugt.   Das Medikament, ...
(Date:9/1/2015)... N.J. , Sept. 1, 2015  ContraVir Pharmaceuticals, ... on the development and commercialization of targeted antiviral therapies, ... & Renshaw 17 th Annual Global Investment Conference ... place September 8-10, 2015 at The St. Regis Hotel ... James Sapirstein , Chief Executive Officer, ...
Breaking Biology Technology:Biovista sponsert die Forschung von Wylder Nation Foundation zum Thema Mangel an saurer Sphingomyelinase 2Temarry Recycling’s New $100,000 Waste to Energy Renovation 2Das Patent von Swecure zur Verhinderung von Allergien bei Kindern wird in den USA zugelassen 2ContraVir to Present at Rodman & Renshaw 17th Annual Global Investment Conference 2
... tissues normally discarded after surgical procedures could be a ... New research from BioMed Central,s open access Journal ... that human fallopian tubes are abundant in mesenchymal stem ... of cell types. It has previously been ...
... New research by a team of University of Toronto scientists ... variety of electronic devices including digital cameras. , Researchers ... digital camera that benefits from a phenomenon known as ... electrical current from a device that takes advantage of MEG. ...
... /PRNewswire-FirstCall/ - Following the announcement on April 30, 2009, ... Human Bionics Inc. ("Victhom", TSX: VHB) and Otto Bock ... of the transaction contemplated by the partnership agreement and ... the concurrent restructuring of its outstanding convertible debentures by ...
Cached Biology Technology:Victhom announces completion of joint venture agreement with Otto Bock for Neurobionix activities 2Victhom announces completion of joint venture agreement with Otto Bock for Neurobionix activities 3Victhom announces completion of joint venture agreement with Otto Bock for Neurobionix activities 4
...
...
... Cultrex High Protein Concentration Basement Membrane ... use in in vivo applications where ... times, increased gel strength, and elevated ... has the advantage of lot-to-lot consistency ...
mitochondrial proteins (human heart) for 2-D gel electrophoresis *5 mg/mL*...
Biology Products: