Navigation Links
Nano-tech makes medicine greener

Over the last 5 years the Bionano Group at the Nano-Science Center and the Department of Neuroscience and Pharmacology at the University of Copenhagen has been working hard to characterise and test how molecules react, combine together and form larger molecules, which can be used in the development of new medicine.

The researchers' breakthrough, as published in the prestigious journal Nature Nanotechnology, is that they are able to work with reactions that take place in very small volumes, namely 10-19 liters. This is a billion times smaller than anyone has managed to work with before. Even more intriguing is the ability to do so in parallel for millions of samples on a single chip.

"We are the first in the world to demonstrate that it is possible to mix and work with such small amounts of material. When we reach such unprecedented small volumes we can test many more reactions in parallel and that is the basis for the development of new drugs. In addition, we have reduced our use of materials considerably and that is beneficial to both the environment and the pocketbook," says professor Dimitrios Stamou, who predicts that the method will be of interest to industry because it makes it possible to investigate drugs faster, cheaper and greener.

The team of professor Stamou reached such small scales because they are working with self-assembling systems. Self-assembling systems, such as molecules, are biological systems that organise themselves without outside control.

This occurs because some molecules fit with certain other molecules so well that they assemble together into a common structure. Self-assembly is a fundamental principle in nature and occurs at all the different size scales, ranging from the formation of solar systems to the folding of DNA.

"By using nanotechnology we have been able to observe how specific self-assembling systems, such as biomolecules, react to different substances and have used this knowledge to develop the method. The self-assembling systems consist entirely of biological materials such as fat and as a result do not impact the environment, in contrast to the materials commonly used in industry today (e.g. plastics, silicon and metals). This and the dramatic reduction in the amount of used materials makes the technique more environment friendly, 'greener'," explains Dimitrios Stamou, who is part of the Synthetic Biology Center and director of the Lundbeck Center Biomembranes in Nanomedicine.


Contact: Dimitrios Stamou
University of Copenhagen

Related biology news :

1. Trustee makes donation to start new solar energy research center at Rensselaer
2. What makes an axon an axon?
3. Feed a cold, feed a fever: Research shows calorie cut makes it harder to fight flu
4. Fly guy makes memory breakthrough
5. Our unconscious brain makes the best decisions possible
6. Biophysical Reviews makes debut in 2009
7. Tree lizard’s quick release escape system makes jumpers turn somersaults
8. Rett Syndrome Research Trust advisor makes significant discovery
9. Peptides-on-demand: McGill researchers radical new green chemistry makes the impossible possible
10. Mount Sinai Hospital researcher makes stem cell breakthrough
11. Red wine vs. white? It makes no difference when it comes to breast-cancer risk
Post Your Comments:
(Date:6/20/2016)... Securus Technologies, a leading provider of ... safety, investigation, corrections and monitoring announced that after ... secured the final acceptance by all three (3) ... Systems (MAS) installed. Furthermore, Securus will have contracts ... by October, 2016. MAS distinguishes between legitimate wireless ...
(Date:6/9/2016)... , June 9, 2016 ... Police deploy Teleste,s video security solution to ensure the safety ... France during the major tournament Teleste, ... communications systems and services, announced today that its video security ... to back up public safety across the country. ...
(Date:6/2/2016)... YORK , June 2, 2016   The Weather ... is announcing Watson Ads, an industry-first capability in which consumers ... by being able to ask questions via voice or text ... Marketers have long sought ... the consumer, that can be personal, relevant and valuable; and ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... 24, 2016 , ... While the majority of commercial spectrophotometers and fluorometers use ... 6000i models are higher end machines that use the more unconventional z-dimension of 20mm. ... from the bottom of the cuvette holder. , FireflySci has developed several Agilent ...
(Date:6/23/2016)... 23, 2016   Boston Biomedical , an ... designed to target cancer stemness pathways, announced that ... Orphan Drug Designation from the U.S. Food and ... cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin is ... inhibit cancer stemness pathways by targeting STAT3, and ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute approval ... of microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... launch of the Supplyframe Design Lab . Located in Pasadena, Calif., the ... future of how hardware projects are designed, built and brought to market. , ...
Breaking Biology Technology: