Navigation Links
Nano-paper filter removes viruses
Date:3/31/2014

Nanotechnology and Functional Materials, Uppsala University have developed a paper filter, which can remove virus particles with the efficiency matching that of the best industrial virus filters. The paper filter consists of 100 percent high purity cellulose nanofibers, directly derived from nature.

The research was carried out in collaboration with virologists from the Swedish University of Agricultural Sciences/Swedish National Veterinary Institute and is published in the Advanced Healthcare Materials journal.

Virus particles are very peculiar objects- tiny (about thousand times thinner than a human hair) yet mighty. Viruses can only replicate in living cells but once the cells become infected the viruses can turn out to be extremely pathogenic. Viruses can actively cause diseases on their own or even transform healthy cells to malignant tumors.

"Viral contamination of biotechnological products is a serious challenge for production of therapeutic proteins and vaccines. Because of the small size, virus removal is a non-trivial task, and, therefore, inexpensive and robust virus removal filters are highly demanded" says Albert Mihranyan, Associate Professor at the Division of Nanotechnology and Functional Materials, Uppsala University, who heads the study.

Cellulose is one of the most common materials to produce various types of filters because it is inexpensive, disposable, inert and non-toxic. It is also mechanically strong, hydrophyllic, stable in a wide range of pH, and can withstand sterilization e.g. by autoclaving. Normal filter paper, used for chemistry, has too large pores to remove viruses.

The undergraduate student Linus Wgberg, Professor Maria Strmme, and Associate Professor Albert Mihranyan at the Division of Nanotechnology and Functional Materials, Uppsala University, in collaboration with virologists Dr. Giorgi Metreveli, Eva Emmoth, and Professor Sndor Belk from the Swedish University of Agricultural Sciences (SLU)/Swedish National Veterinary Institute (SVA), report a design of a paper filter which is capable of removing virus particles with the efficiency matching that of the best industrial virus filters. The reported paper filter, which is manufactured according to the traditional paper making processes, consists of 100 percent high purity cellulose nanofibers directly derived from nature.

The discovery is a result of a decade long research on the properties of high surface area nanocellulose materials, which eventually enabled the scientists to tailor the pore size distribution of their paper precisely in the range desirable for virus filtration.

Previously described virus removal paper filters relied heavily on interception of viruses via electrostatic interactions, which are sensitive to pH and salt concentrations, whereas the virus removal filters made from synthetic polymers and which rely on size-exclusion are produced through tedious multistep phase-inversion processing involving hazardous solvents and rigorous pore annealing processing.

Incidentally, it was the Swedish chemist J.J. Berzelius (1779-1848), one of the most famous alumni of Uppsala University, who was the first one to use the pure wet-laid-all-rag paper for separation of precipitates in chemical analysis. In a way, the virus removal nano-paper filter developed by the Uppsala scientists is the modern day analogue of the widely popular Swedish Filter Paper developed by Berzelius nearly two centuries ago.


'/>"/>

Contact: Albert Mihranyan
albert.mihranyan@angstrom.uu.se
46-701-679-037
Uppsala University
Source:Eurekalert

Related biology news :

1. Special air filter blocks small particles called UFPs from getting inside cars
2. Living biofilters could reduce greenhouse gas emissions
3. Solar-powered nanofilters pump in antibiotics to clean contaminated water
4. Medical societies to launch large-scale study on vein filter use
5. Synthetic biofilter wins through to the top Sweet 16 in Boston
6. A brain filter for clear information transmission
7. Ordinary conditioner removes head lice eggs as effectively as special products
8. New research seeks beneficial qualities of viruses
9. Gold nanoparticles help to develop a new method for tracking viruses
10. Research uncovers key difference between our bodies fight against viruses and bacteria
11. Better preparedness against Tamiflu-resistant influenza viruses
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2016)... -- The American College of Medical Genetics and Genomics was once ... one of the fastest-growing trade shows during the Fastest 50 ... Las Vegas . Winners ... each of the following categories: net square feet of paid ... The 2015 ACMG Annual Meeting was ranked 23 out of ...
(Date:6/16/2016)... , June 16, 2016 ... is expected to reach USD 1.83 billion by ... View Research, Inc. Technological proliferation and increasing demand ... are expected to drive the market growth. ... The development of advanced multimodal techniques ...
(Date:6/3/2016)... 3, 2016 Das ... Nepal hat ein 44 ... geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, ... Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte ... Januar teilgenommen, aber Decatur wurde als konformste ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... on a range of subjects including policies, debt and investment ... Speaking at a lecture to the Canadian Economics ... the country,s inflation target, which is set by both the ... "In certain areas there needs to be frequent ... not sit down and address strategy together?" He ...
(Date:6/23/2016)... WA (PRWEB) , ... June 23, 2016 , ... ... announces the release of its second eBook, “Clinical Trials Patient Recruitment and Retention ... recruitment and retention in this eBook by providing practical tips, tools, and strategies ...
(Date:6/23/2016)... SPRING, Md. , June 23, 2016 A ... collected from the crime scene to track the criminal down. ... and the U.S. Food and Drug Administration (FDA) uses DNA ... Sound far-fetched? It,s not. The ... genome sequencing to support investigations of foodborne illnesses. Put as ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge ... envision new ways to harness living systems and biotechnology, ... Art (MoMA) in New York City ... 130 participating students, showcased projects at MoMA,s Celeste Bartos ... Paola Antonelli , MoMA,s senior curator of architecture and ...
Breaking Biology Technology: