Nanotechnology and Functional Materials, Uppsala University have developed a paper filter, which can remove virus particles with the efficiency matching that of the best industrial virus filters. The paper filter consists of 100 percent high purity cellulose nanofibers, directly derived from nature.
The research was carried out in collaboration with virologists from the Swedish University of Agricultural Sciences/Swedish National Veterinary Institute and is published in the Advanced Healthcare Materials journal.
Virus particles are very peculiar objects- tiny (about thousand times thinner than a human hair) yet mighty. Viruses can only replicate in living cells but once the cells become infected the viruses can turn out to be extremely pathogenic. Viruses can actively cause diseases on their own or even transform healthy cells to malignant tumors.
"Viral contamination of biotechnological products is a serious challenge for production of therapeutic proteins and vaccines. Because of the small size, virus removal is a non-trivial task, and, therefore, inexpensive and robust virus removal filters are highly demanded" says Albert Mihranyan, Associate Professor at the Division of Nanotechnology and Functional Materials, Uppsala University, who heads the study.
Cellulose is one of the most common materials to produce various types of filters because it is inexpensive, disposable, inert and non-toxic. It is also mechanically strong, hydrophyllic, stable in a wide range of pH, and can withstand sterilization e.g. by autoclaving. Normal filter paper, used for chemistry, has too large pores to remove viruses.
The undergraduate student Linus Wgberg, Professor Maria Strmme, and Associate Professor Albert Mihranyan at the Division of Nanotechnology and Functional Materials, Uppsala University, in collaboration with virologists Dr. Giorgi Metreveli, Eva Emmoth, and Professor Sndor Belk from the Swedish University of Agri
|Contact: Albert Mihranyan|