Navigation Links
NYU School of Medicine receives $8.2M grant from NIDDK to continue urological disease research
Date:8/17/2010

NEW YORK, NY August 17, 2010 The Urothelial Biology Team at NYU School of Medicine received an $8.2 million, five-year program project (P01) grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health to continue groundbreaking research on bladder biology and diseases including urinary tract infection (UTI).

The Urothelial Biology Team is an integral unit of the NYU Center of Excellence on Urological Diseases consisting of professors from multiple disciplines. Led by Tung-Tien Sun, PhD, Rudolph L. Baer Professor of Dermatology and professor in the Departments of Cell Biology, Pharmacology and Urology, the team includes Xiangpeng Kong, PhD, associate professor of biochemistry, Gert Kreibich, PhD, professor of cell biology, Angel Pellicer, MD, PhD, professor of pathology, and Xue-Ru Wu, MD, professor of urology and pathology and vice chairman for urological research.

"We are pleased to have received this grant from NIDDK to support this multidisciplinary research program," said Vivian S. Lee, MD, PhD, MBA is senior vice president and vice dean for science, chief scientific officer of NYU Langone Medical Center. "The work of the Urothelial Biology Team is a testament to NYU School of Medicine's commitment to fostering collaborative research in an effort to understand the root cause of diseases and develop novel strategies for treatment."

The team is currently studying how the urothelium, the main cell type that covers the luminal surface of the bladder, forms a highly effective barrier, and how bacteria cause urinary tract infection (UTI). The team hopes to understand how the disease-causing bacteria interact with and invade the host urothelial cells, a process common in recurrent UTI. UTI is the most common cause of bloodstream infections by E. coli which cause 40,000 deaths from sepsis each year in the United States.1 Uncomplicated UTIs alone are responsible for an estimated $1-2 billion in direct healthcare costs in the United States annually.1 Abnormalities in bladder urothelial cells are involved in several other important urologic diseases including overactive bladder, painful bladder syndrome, which mainly affects women 2, and bladder cancer which is the fourth most common cancer in men 3 and the most expensive cancer to manage. Treatment of these diseases costs the American public almost $11 billion annually.4

"Dr. Sun and his multidisciplinary team are uniquely poised to address key questions regarding the structure and function of the bladder urothelium," said Chris Mullins, PhD, director of Basic Cell Biology Programs, Division of Kidney, Urologic and Hematologic Diseases, NIDDK. "Their work is expected to yield significant insights into the role these cells play in urinary tract infections."


'/>"/>

Contact: Lisa Greiner
lisa.greiner@nyumc.org
212-404-3532
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Related biology news :

1. Color My Pyramid nutrition education program battles obesity in DC schools
2. identiMetrics & BIO-key(R) Provide Biometric Finger Scanning for School Food Service Nationwide
3. NJIT sustainability expert to discuss high performance schools at seminar
4. Students eat more whole grains when its gradually added to school lunch
5. Eliminating soda from school diets does not affect overall consumption
6. High school students paper published in prestigious college math journal
7. David Rose to present Howe School lecture on new technologies and business models, Jan. 29
8. Physically fit kids do better in school
9. Results of the third school nutrition dietary assessment study published
10. New York, Florida schools win awards at national student competition
11. Names turn preschoolers into vegetable lovers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2017)... Feb 10, 2017 Research and ... "Personalized Medicine - Scientific and Commercial Aspects" to ... ... Diagnosis is integrated with therapy for selection of treatment as ... detection and prevention of disease in modern medicine. Biochip/microarray technologies ...
(Date:2/8/2017)... YORK , Feb. 8, 2017 About ... individual,s voice to match it against a stored ... such as pitch, cadence, and tone are compared ... require minimal hardware installation, as most PCs already ... for different transactions. Voice recognition biometrics are most ...
(Date:2/8/2017)... Report Highlights ... The global synthetic-biology market reached nearly $3.9 billion in ... a compound annual growth rate (CAGR) of 24.0% through 2021. ... for synthetic biology. - Analyses of global market trends, with ... annual growth rates (CAGRs) through 2021. - Coverage of core ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... ... March 23, 2017 , ... AxioMed president, Jake Lubinski, describes ... characteristics when deformed, which is identical to how the human discs work to ... and return to its natural state along a hysteresis curve, exactly like a ...
(Date:3/23/2017)... -- GlobeImmune, Inc. today announced it has entered into a ... of its common stock to NantCell, Inc., a member ... sale of its common stock, NantCell has agreed to ... 200,000 shares, an estimated $2.0 million in value, of ... to enter into this strategic agreement with NantCell," said ...
(Date:3/23/2017)... York , March 23, 2017 According ... plasma products and derivatives market is fragmented due to the presence of ... such as Proliant, Thermo Fisher , and Sigma-Aldrich, compete with ... these three companies, collectively, held more than 76% of this market ... As ...
(Date:3/22/2017)... ... March 22, 2017 , ... Researchers face a ... lab samples to full-size tissues, bones, even whole organs to implant in people ... delivers blood deep into the developing tissue. , Current bioengineering techniques, including ...
Breaking Biology Technology: