NYU Langone Medical Center's tip sheet to the International Conference on Alzheimer's Di...(u and other compounds among individuals ...)

Date:7/25/2008

u and other compounds among individuals who would develop Alzheimer's compared to those individuals who didn't progress from mild cognitive impairment over the two-year period. This preliminary study suggests that combining these tests could help predict which individuals with mild cognitive impairment are at the highest risk for developing Alzheimer's disease.
Presentation # P3-067

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Big Immune Response to Common Mouth Bacteria Linked to Alzheimer's.
Angela R Kamer, D.M.D., M.S., PhD., Assistant Professor, College of Dentistry, New York University
EMBARGOED FOR RELEASE UNTIL SUNDAY, July 27, 2008, at 12:30 p.m. CT

In a study investigating the link between Alzheimer's disease and a heightened inflammatory-immune response, NYU researchers found that twice as many subjects with probable Alzheimer's disease tested positive for antibodies in their plasma against a type of bacteria that is commonly found in the mouth. The pioneering study supports a growing body of evidence that associates notable immune changes with a means of predicting and classifying Alzheimer's disease. Together with other immune markers associated with Alzheimer's disease, antibodies to these periodontal bacteria could serve to better understand the causes and mechanisms of the disease, the researchers say.
Presentation # P1-348

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Signs of Brain Disease among Healthy Individuals
Lidia Glodzik, MD, PhD, Research Physician, Center for Brain Health at NYU Langone Medical Center
EMBARGOED FOR RELEASE UNTIL TUESDAY, July 29, 2008 at 12:30 p.m. CT

NYU researchers identified signs of pathology before the clinically noticeable stages of mild cognitive impairment that normally precede Alzheimer's disease. The study involved a cognitively normal group of people ages 40 to 86. It found that higher levels of tau protein in the cerebrospinal fluid correlated with lower grey matter density in brain regions that
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Contact: Bob Brody bobbrody@hotmail.com 212-404-3555 NYU Langone Medical Center / New York University School of Medicine Source:Eurekalert

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