Experts from The Cancer Institute at NYU Langone Medical Center presented new research findings at the American Association for Cancer Research 102nd Annual Meeting 2011 held April 2-6, 2011 in Orlando, Florida. NYU Cancer Institute researchers discussed various breakthroughs such as a novel test for early-stage asbestos-related pulmonary cancer, a promising treatment strategy for glioblastomas, genome-wide mapping of nickel-related cancer and greater understanding of melanoma and bladder cancer.
Detection of Mesothelioma in Asbestos Exposed Individuals with Aptamer Proteomic Technology
Author: Harvey I. Pass, MD, professor, Cardiothoracic Surgery and Surgery
Malignant pleural mesothelioma is an aggressive, asbestos-related pulmonary cancer that develops in the lining of the lungs. Researchers investigated a novel protein test to detect early-stage, asbestos-related pulmonary cancer. The new test can accurately identify proteins secreted from cancerous tumors caused by asbestos exposure. In a blinded test researchers detected 15 of 19 cases of stage 1 or stage 2 malignant pleural mesothelioma. The goal of the new diagnostic test is to find the cancer early enough to effectively treat it. The test called "Multiplex SOMAmer Assay" by SomaLogic, Inc. uses SOMAmers, chemically modified single-stranded DNA molecules to bind specifically to target proteins and quantify biomarkers. The test successfully measures 19 protein biomarkers for malignant pleural mesothelioma and quantifies the small amount of proteins secreted by tumor cells.
Abstract 2812: Monday, April 4, 2011, 8:30 AM
Learn more : http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=3143326d-b0b1-4408-9077-09ac88372faa&cKey=13dffe63-f569-45c7-ab9d-26c8e6bf
|Contact: Lauren Woods|
NYU Langone Medical Center / New York University School of Medicine