Navigation Links
NYSCF scientists 1 step closer to cell therapy for multiple sclerosis patients
Date:7/24/2014

NEW YORK, NY (July 24, 2014) Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute are one step closer to creating a viable cell replacement therapy for multiple sclerosis from a patient's own cells.

For the first time, NYSCF scientists generated induced pluripotent stem (iPS) cells lines from skin samples of patients with primary progressive multiple sclerosis and further, they developed an accelerated protocol to induce these stem cells into becoming oligodendrocytes, the myelin-forming cells of the central nervous system implicated in multiple sclerosis and many other diseases.

Existing protocols for producing oligodendrocytes had taken almost half a year to produce, limiting the ability of researchers to conduct their research. This study has cut that time approximately in half, making the ability to utilize these cells in research much more feasible.

Stem cell lines and oligodendrocytes allow researchers to "turn back the clock" and observe how multiple sclerosis develops and progresses, potentially revealing the onset of the disease at a cellular level long before any symptoms are displayed. The improved protocol for deriving oligodendrocyte cells will also provide a platform for disease modeling, drug screening, and for replacing the damaged cells in the brain with healthy cells generated using this method.

"We are so close to finding new treatments and even cures for MS. The enhanced ability to derive the cells implicated in the disease will undoubtedly accelerate research for MS and many other diseases," said Susan L. Solomon, NYSCF Chief Executive Officer.

"We hope that this protocol will be helpful to the MS field and the larger scientific community to better understand human oligodendrocyte biology and the process of myelination. This is the first step towards very exciting studies: the ability to generate human oligodendrocytes in large amounts will serve as an unprecedented tool
'/>"/>

Contact: David McKeon
dmckeon@nyscf.org
212-365-7440
New York Stem Cell Foundation
Source:Eurekalert

Page: 1 2

Related biology news :

1. NYSCF scientists develop 3-D stem cell culture technique to better understand Alzheimers disease
2. NYSCF scientists develop new protocol to ready induced pluripotent stem cell clinical application
3. NYSCF and NIH create cell models of rare and undiagnosed diseases
4. NYSCF and eagle-i Network co-develop iPS cell database
5. NYSCF partners with Beyond Batten Disease Foundation to fight juvenile Batten disease
6. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
7. Queens scientists seek vaccine for Pseudomonas infection
8. Scientists produce eye structures from human blood-derived stem cells
9. American Society of Plant Biologists honors early career women scientists
10. Brandeis scientists win prestigious prize for circadian rhythms research
11. Scientists discover new method of proton transfer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/8/2015)...  Infinisource, a leading provider of SaaS-based Human Capital ... leading supplier of biometric identification and security solutions, ... advanced biometrically-enabled time clock, the companies announced today. ... setting a bold, new standard for the collection ... and mid-size employer. When connected to the iSolved ...
(Date:4/2/2015)... According to preliminary estimates Fingerprint ... higher than 125 MSEK. This exceeds the guidance provided ... revenues for Q1 2015 would be in line with ... 2014. The operating result for the first quarter is ... report will as previously communicated be published on May ...
(Date:3/31/2015)... March 31, 2015  Elephant Talk Communications Corp. (NYSE ... provider of Software Defined Network Architecture (ET Software DNA® ... revenue of approximately $20.4 million for the year ended ... million for the year ended December 31, 2013. ... Company had completed its multi-year transition away from its ...
Breaking Biology News(10 mins):iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3Fingerprint Cards Revises Revenues for Q1 2015 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 2Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 3Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 4Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 5Elephant Talk Reports 2014 Fourth Quarter and Year End Financial Results 6
... will host its 2014 Biodefense and Emerging Diseases Research ... Hotel in Washington, DC. The purpose of this ... out research to defend against the threat of bioterrorism ... recognizing that emerging infectious diseases serve as a paradigm ...
... RNA is not merely a transitional state between DNA and ... how genes are turned into a protein product. Gaining a ... on diseases that arise when this function goes awry. ... up to offer a new method for elucidating RNA regulation. ...
... deadly form of primary malignant brain cancer accounting for ... in adults between the ages of 45 and 70. ... only temporarily contained by combined surgery, chemotherapy and radiation ... in an average patient survival time of less than ...
Cached Biology News:Penn biologists establish new method for studying RNA's regulatory 'footprint' 2Penn biologists establish new method for studying RNA's regulatory 'footprint' 3Stopping tumors in their path 2
(Date:4/17/2015)... BellBrook Labs announced today that ... the powerful Orthogonal Pooled Screening (OPS) Platform developed ... the Lankenau Institute for Medical Research (LCGC) in ... improve successful drug discovery outcomes using far more ... libraries available nowhere else, coupled to a state-of-the-art ...
(Date:4/16/2015)... (PRWEB) April 16, 2015 ... data solutions driven by Semantic Web technology, and ... specialist information and services for the academic and ... that its joint solution ‘Smart Data Lake for ... finalist for the 2015 Bio-IT ‘Best of Show’ ...
(Date:4/16/2015)... Proove Biosciences , Inc. is pleased ... for the 2015 BIO International Convention. Hosted by ... Convention will take place June 15-18 at the Pennsylvania ... BIO contest, industry leaders will be voting for companies ... The community voting period began on April 14, 2015 ...
(Date:4/16/2015)... (PRWEB) April 16, 2015 According ... overexertion involving an outside source was ranked first ... includes injuries related to lifting, pushing, pulling, holding, ... in direct costs. The David Round Company takes ... committed to working hard to develop and design ...
Breaking Biology Technology:BellBrook Labs and Lankenau Institute Partner to Accelerate Drug Discovery using Orthogonal Pooled Screening 2Cambridge Semantics and Informa Named Bio-IT Award Finalist for Smart Data Lake Solution for Clinical Trial and Competitive Intelligence 2Cambridge Semantics and Informa Named Bio-IT Award Finalist for Smart Data Lake Solution for Clinical Trial and Competitive Intelligence 3Proove Bisociences to Participate in the Buzz of BIO at the 2015 BIO International Convention 2Proove Bisociences to Participate in the Buzz of BIO at the 2015 BIO International Convention 3The David Round Company Helps Companies Meet OSHA Standards by Combining Safety, Ergonomics, and Productivity 2
... is known for its innovation and ability to take ... changing the dynamics and places like South Korea, China ... too. India, for example, is gaining ground in software ... that we hear so much about. The advantages the ...
... an idea of the intricacy possible in machining and tool ... EDM, you can tunnel into the thin side of a ... and leave the top and lower surfaces of that same ... used by Steve Plendl, the lead EDM instructor at ...
... exploring new technologies that will result in a more ... Systems based in Menasha, Wisconsin is strategically investing ... of care it offers by focusing on those initiatives ... ,Affinity has been able to prioritize such investments as ...
Cached Biology Technology:Keeping Innovation Vibrant in the U.S. 2Powerful, Intricate Technology Taught in CVTCs New Tool and Die Program 2Powerful, Intricate Technology Taught in CVTCs New Tool and Die Program 3Affinity Health Streamlines IT Governance 2
...
...
... data entry by collecting data from any ... Collect is extremely easy to use ... data entry. An excellent solution for ... spectrophotometers, force gauges, digital calipers, bar code ...
... the autofluorescent pigment lipofuscin accumulates in ... including neurons. The presence of lipofuscin ... fluorescence microscopy in the central nervous ... and emission spectra, which overlaps with ...
Biology Products: