Navigation Links
NUS study shows effectiveness of common anti-malarial drug in controlling asthma
Date:8/1/2014

Asthmatic patients may soon have a more effective way to control the condition, thanks to a new pharmacological discovery by researchers from the National University of Singapore (NUS).

The team, led by Associate Professor Fred Wong from the Department of Pharmacology at the NUS Yong Loo Lin School of Medicine, together with Dr Eugene Ho Wanxing, a recent PhD graduate from the Saw Swee Hock School of Public Health at NUS, discovered that artesunate, a common herbal-based anti-malarial drug, can be used to control asthma, with better treatment outcomes than other drugs currently available.

In their latest work, the team revealed for the first time that artesunate is able to suppress airway inflammation and produce an array of anti-inflammatory effects similar to those by dexamethasone, the most potent steroid currently available, and with less side effects. This breakthrough discovery was first published in the journal Metabolomics on 16 July 2014.

Earlier this year, the NUS team was invited by renowned journal Pharmacology and Therapeutics to pen a comprehensive review of the pharmacological effects of artesunate, and the review article was published in the journal in April 2014.

The quest for better asthma therapeutics

Asthma is an incurable lung disease that inflames and narrows the airways, causing recurring periods of wheezing, chest tightness, coughing and shortness of breath. It is a chronic condition that affects people of all ages, but it most often starts during childhood.

To address the global unmet demand for better therapeutics to control allergic asthma, Dr Ho explored the therapeutic values of artesunate, which is herbal-based, as an alternative drug candidate. This study was part of Dr Ho's final-year project when he was pursuing a Bachelor of Science in Life Sciences at NUS. His initial findings demonstrated that artesunate possessed promising anti-inflammatory potent
'/>"/>

Contact: Carolyn Fong
carolyn@nus.edu.sg
65-651-65399
National University of Singapore
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Study of bigeye tuna in Northwest Atlantic uses new tracking methods
2. UF study advances DNA revolution, tells butterflies evolutionary history
3. Study of twins discovers gene mutation linked to short sleep duration
4. Study finds benefits to burning Flint Hills prairie in fall and winter
5. UT Dallas study reveals effect of loud noises on brain
6. New international tree nut council study looks at nuts, diabetes and metabolic syndrome
7. Study: Marine pest provides advances in maritime anti-fouling and biomedicine
8. Healthy lifestyle may buffer against stress-related cell aging, study says
9. Study suggests disruptive effects of anesthesia on brain cell connections are temporary
10. Study finds Europes habitat and wildlife is vulnerable to climate change
11. Dinosaurs fell victim to perfect storm of events, study shows
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NUS study shows effectiveness of common anti-malarial drug in controlling asthma
(Date:5/5/2015)... May 5, 2015, NXT-ID, Inc. (NASDAQ: NXTD ... on the growing mobile commerce market, reminds investors and media ... Officer, is presenting  at CARTES SECURE CONNEXIONS AMERICA 2015, held ... The three-day conference is organized into a ... in is themed Global Fraud: Where is the Trust ...
(Date:4/27/2015)... Apr. 27, 2015 NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market, announces ... pre-order customers the first week of May, 2015 and ... of May. Gino Pereira , ... for the company as Wocket® enters the consumer market. ...
(Date:4/21/2015)... 21, 2015 High crime ... are boosting access control systems market in ... a recently published report by TechSci Research " Saudi ... access control systems market in Saudi Arabia ... 2020.The access control systems market in the Kingdom is ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3
... 30, 2014 Scientists from the Florida campus of ... $1.8 million from the National Cancer Institute of the ... that underlie lung cancer and to use this information ... TSRI associate professor, will be principal investigator of the ...
... Researchers at the National Institute of Standards and Technology ... model of a simplified cell membrane to accurately detect ... disease, bacterial vaginosis (BV), at extraordinarily low concentrations. The ... to improve disease diagnosis. Caused by the bacteria ...
... (Lebanon, NH, 1/30/14) Dartmouth researchers developed a new biological ... (PHPN), to identify underlying genetic connections between different diseases ... The PHPN mines the data present in large ... or pathways and expresses them in a visual form. ...
Cached Biology News:NIST cell membrane model studied as future diagnostic tool 2Dartmouth researchers develop new tool to identify genetic risk factors 2
(Date:5/26/2015)... 2015 Pharmaco-Kinesis Corporation (PKC) announced today that ... Shutters on the Beach in Santa Monica, ... the Company,s innovative Metronomic Biofeedback Pump (MBP), a fully ... over time to a target site of the human ... system in real-time.  ...
(Date:5/26/2015)... , May 26, 2015  Asterias Biotherapeutics, Inc. ... emerging field of regenerative medicine, today announced that all ... 2014 were exercised prior to their expiry on June ... of $11.7 million. "We thank our shareholders ... President and CEO of Asterias. "This exercise of warrants ...
(Date:5/26/2015)... , May 26, 2015 US-Australian drug discovery and development ... it will present at the 2015 Marcum MicroCap Conference ... at the Grand Hyatt Hotel. The ... CEO, is scheduled to begin at 9.30 a.m. ET and will ... to http://wsw.com/webcast/marcum3/nvgn . The annual Marcum MicroCap ...
(Date:5/25/2015)... Where is the universe expanding to? ... honest answer is that nobody is entirely sure." , ... the month of June, starting with the ULI Florida ... to top tech trends. And one of the most ... universe is expanding to. According to Einstein’s theory of ...
Breaking Biology Technology:Pharmaco-Kinesis Corporation Convenes Third Neuro-Oncology Clinical Advisory Board Meeting 2Pharmaco-Kinesis Corporation Convenes Third Neuro-Oncology Clinical Advisory Board Meeting 3Pharmaco-Kinesis Corporation Convenes Third Neuro-Oncology Clinical Advisory Board Meeting 4Pharmaco-Kinesis Corporation Convenes Third Neuro-Oncology Clinical Advisory Board Meeting 5Asterias Biotherapeutics Receives $11.7 Million in Proceeds from Exercise of Warrants 2Asterias Biotherapeutics Receives $11.7 Million in Proceeds from Exercise of Warrants 3Novogen to Present at the 2015 Marcum Microcap Conference 2Novogen to Present at the 2015 Marcum Microcap Conference 3Novogen to Present at the 2015 Marcum Microcap Conference 4Futurist Jack Uldrich Says Embracing Our Ignorance is the Key to Unlearning 2Futurist Jack Uldrich Says Embracing Our Ignorance is the Key to Unlearning 3
... 26 Campbell Alliance, the leading,management consulting firm ... that George Schmidt, Vice President,in the firm,s Sales ... Force Effectiveness (SFE) conference. The event will be ... Convencions Internacional in Barcelona, Spain., Mr. Schmidt,s ...
... CLAREMONT, Calif., March 26 /Xinhua-PRNewswire-FirstCall/,-- Kiwa Bio-Tech Products ... for the year ended December 31, 2007 were,$9,129,779 ... Net sales from continuing operations were $9,129,779 ... 2007 and 2006, respectively,representing an increase of $6,623,064 ...
... Md., March 26 PharmAthene, Inc.,(Amex: ... the development and,commercialization of medical countermeasures against ... has been awarded a contract,modification providing an ... of Protexia(R), the Company,s broad spectrum chemical ...
Cached Biology Technology:Campbell Alliance Sales Practice to Conduct Workshop at EyeForPharma SFE Europe Conference 2Campbell Alliance Sales Practice to Conduct Workshop at EyeForPharma SFE Europe Conference 3Kiwa Bio-Tech Year-End Revenues Increase 264% - Exceed $9.1 Million 2Kiwa Bio-Tech Year-End Revenues Increase 264% - Exceed $9.1 Million 3Kiwa Bio-Tech Year-End Revenues Increase 264% - Exceed $9.1 Million 4Kiwa Bio-Tech Year-End Revenues Increase 264% - Exceed $9.1 Million 5Kiwa Bio-Tech Year-End Revenues Increase 264% - Exceed $9.1 Million 6Kiwa Bio-Tech Year-End Revenues Increase 264% - Exceed $9.1 Million 7Department of Defense Awards $5.8 Million Contract Modification Providing Additional Funding for PharmAthene's Protexia(R) Program 2Department of Defense Awards $5.8 Million Contract Modification Providing Additional Funding for PharmAthene's Protexia(R) Program 3Department of Defense Awards $5.8 Million Contract Modification Providing Additional Funding for PharmAthene's Protexia(R) Program 4
Antibodies were affinity purified using epitopes specific to USP33 immobilized on solid support....
... antibody recognizes 30% of IgM-rheumatoid ... It does not cross-react with IgM, ... factor nor with pooled F(Ab)2 fragments. ... ELISA to detect rheumatoid factor. Product ...
...
...
Biology Products: