Navigation Links
NUS-led research team discovers how bacteria sense salt stress
Date:7/9/2012

A team of scientists led by Assistant Professor Ganesh S Anand and Professor Linda J. Kenney from the National University of Singapore (NUS) Department of Biological Sciences (DBS) and the Mechanobiology Institute (MBI) has discovered how bacteria respond to salts in their environment and the ways in which salts can alter the behaviour of specialised salt sensor bacterial proteins.

This novel finding sheds light on how microbes detect levels of salts or sugars in their watery environments a problem in biology that has been studied for more than 30 years.

The NUS scientists found that microbes do this by specialised molecules or proteins on the bacterial surface that change shape in response to changes in salt concentration. This is relevant not only to bacteria, but also cells from all organisms which detect and respond to changes in environmental salts and sugars.

The scientists from NUS and the University of Illinois-Chicago (UIC) first published their findings in the EMBO Journal on 30 May 2012.

Salt detecting proteins are like springs

Bacteria have elaborate mechanisms for sensing and responding to changes in the environment. One of the important environmental stresses for bacteria is the changing concentration of salts. For instance, some can live in fresh water (a low salt environment) or in the guts of humans (high salt environment).

Using a powerful combination of a tool called amide hydrogen/deuterium exchange mass spectrometry (HDXMS), accompanied by molecular biology and biochemistry, the scientists from NUS probed how changes in salt concentrations are sensed by a receptor protein.

They found that salt detecting proteins are like molecular springs, or "slinky toys". The proteins are constantly shifting from a condensed spring form to an extended form. Increasing the salt concentration dampens this spring-like movement, which activates the protein. In other words, th
'/>"/>

Contact: Carolyn FONG
carolyn@nus.edu.sg
65-651-65399
National University of Singapore
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Researchers discover molecule in immune system that could help treat dangerous skin cancer
2. Grant to allow graduate students to research water quantity and quality improvement
3. New research finds increased growth responsible for color changes in coral reefs
4. Special issue of Botany showcases CANPOLIN research
5. Hormones dictate when youngsters fly the nest, says new research
6. Patient-derived stem cells could improve drug research for Parkinsons
7. The EU underpays Madagascar for access to fish: UBC research
8. Researchers moving towards ending threat of West Nile virus
9. All Things Research 2012 roundtable discussion
10. The genomics symposium to boost the further development of cancer research
11. ASU receives prestigious $6.25 million multi-disciplinary research award from Department of Defense
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NUS-led research team discovers how bacteria sense salt stress
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research ... announced the addition of the "Global Facial ... http://photos.prnewswire.com/prnh/20130307/600769 ... the identification of individuals. Facial recognition system measures ... as nose, jaw edges, mouth, and the distance ...
(Date:12/11/2014)... --Research and Markets , ... ) has announced the addition of the ... their offering. One major trend ... multimodal biometric systems. Multimodal biometric systems utilize more ... and identification purposes. This helps to reduce the ...
(Date:12/11/2014)... 10, 2014  Data Sciences International (DSI), the ... a new series of digital telemetry implants to ... M series, part of the PhysioTel™ Digital platform, ... possible physiologic data when incorporating functional endpoints into ... to toxicology studies has evolved from short ECG ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2New telemetry implants expected to change how large animal toxicology studies are conducted 2
... TX -- Researchers at Sam Houston State University and the ... from the criminal justice system in Houston to establish protocols ... by crime labs. , "This is a problem-solving project that ... tested," said Dr. William Wells, who is leading the research ...
... 2011 -- Experts agree that obesity prevention should begin before ... conclusive data, health care providers often have trouble advising parents ... study soon to be published in The Journal of ... may be an effective way to help prevent obesity. ...
... to deliver payloads of cancer-fighting drugs to tumors in ... treatment. But scientists are still at a relatively early ... Although developing nanoparticles that work as "magic bullets" ... is still the goal, the reality is that ...
Cached Biology News:Research to target untested rape kits 2Research to target untested rape kits 3Study suggests prolonged bottle feeding increases the risk of obesity 2Hitting target in cancer fight now easier with new nanoparticle platform, UCLA scientists say 2
(Date:12/17/2014)... , Dec. 16, 2014  Vermillion, Inc. (NASDAQ: ... on gynecologic disease, today announced the next step in ... premier bio-analytics solutions provider with the naming of current ... and Chief Executive Officer, while current Chairman of the ... to serve as Chairman. These changes are effective January ...
(Date:12/17/2014)... LEXINGTON, Mass. , Dec. 17, 2014   ... a biopharmaceutical company developing therapeutic products for rare disorders, ... Healthcare Conference being held in San Francisco, ... , President and Chief Executive Officer, will present on ... p.m. EST).  The presentation will be webcast live and ...
(Date:12/15/2014)... NEW YORK , Dec. 15, 2014  GlassesOff ... Yuval Bar-Gil as an independent director of ... was founder of AeroScout and served as its CEO ... Decker in 2012, a $240 million transaction. Recognized as ... under Mr. Bar-Gil,s leadership, AeroScout provided Wi-Fi -based RFID ...
(Date:12/13/2014)... , Dec. 12, 2014 /CNW/ - MaRS and Virgin Unite ... that they have joined forces to support Canadian entrepreneurs tackling ... Virgin Group Founder was at the MaRS Centre to announce ... national impact venture fund. This fund has $1 million in ... Vancouver -based Mindset Social Innovation Foundation, founded by ...
Breaking Biology Technology:Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3MaRS and Virgin Unite partner to invest in business as a force for good 2MaRS and Virgin Unite partner to invest in business as a force for good 3
... March 18 Syndication Inc., (Pink Sheets: SYNJ), Reports ... of ,Director of Technical Engineering,. The job of the ... budget development of the Company,s Pinnacle Energy Division. The ... wind turbine energy, bio-diesel fuel production, and microwave plasma ...
... 11dhTxB2 to assess aspirin effectDENVER, March 18 ... worldwide developer and marketer of diagnostic test kits, ... Test March 29 - 31 at the American ... The annual meeting will take place in Orlando, ...
... Despite the initial regulatory hiccups, the number of ... increase gradually. The patent expiry of key biopharmaceuticals ... driving the development of biosimilars. In addition, payers, ... drugs due to their safety, efficacy and affordability, ...
Cached Biology Technology:Syndication Inc. Seeks 'DIRECTOR OF TECHNICAL ENGINEERING' for 'PINNACLE ENERGY' - Its New Alternative Energy Subsidiary 2Corgenix to Exhibit AspirinWorks(R) Test at ACC.09 2Corgenix to Exhibit AspirinWorks(R) Test at ACC.09 3The Need for Safe and Affordable Biopharmaceuticals Drives the Development of the European Biosimilars Market, Says Frost & Sullivan 2The Need for Safe and Affordable Biopharmaceuticals Drives the Development of the European Biosimilars Market, Says Frost & Sullivan 3The Need for Safe and Affordable Biopharmaceuticals Drives the Development of the European Biosimilars Market, Says Frost & Sullivan 4
... antibody raised against a partial ... Immunogen: SF3B2 (NP_006833, 592 ... recombinant protein with GST tag. ... NM_006842 ...
...
Mouse monoclonal antibody raised against a partial recombinant ZNF155. NCBI Entrez Gene ID = ZNF155...
Mouse polyclonal antibody raised against a partial recombinant COASY. NCBI Entrez Gene ID = 80347...
Biology Products: